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PIM2: Pim-2 proto-oncogene, serine/threonine kinase
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Gene · 11040

Papers1,338

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,338

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TitleJournalYearPMIDFound bySource
Targeting PIM kinases in cancer and inflammatory disorders: From mechanisms to clinical translation.Eur J Med Chem202642822254PubTator, text miningPubMed
Machine learning-driven identification of PIM2 kinase inhibitors through QSAR modeling and molecular dynamics simulations.J Genet Eng Biotechnol202642749429PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
T Cell-associated Co-expression Module Genes as Prognostic Biomarkers and Predictors of Immunotherapy Response in Head and Neck Squamous Cell Carcinoma.Curr Med Chem202642634197PubTator, text miningPubMed
Comparative Analysis of LPS/IFN-γ and LPS/ATP-Induced Inflammatory Models in BV2 Microglia.Neurochem Res202642566061PubTator, text miningPubMed
In silico DFT study, molecular docking interactions, molecular dynamics and toxicological assessment of selected organochlorine-based pesticides.In Silico Pharmacol202642542631PubTator, text miningPubMed
PAWR augments anti-RNA viral innate immunity by promoting the PIM2-XBP1s-RIG-I signaling axis.Nat Commun202642277020PubTator, text miningPubMed
An orally active dual CBP/p300 degrader targets core dependencies of multiple myeloma.Cell Rep202642228563PubTator, text miningPubMed
Periodontal ligament stem cell-derived exosomal miR-378a programs osteogenic commitment via DAZAP2/SMAD signaling.Biochem Biophys Res Commun202642185189PubTator, text miningPubMed
An explainable ensemble machine learning framework for predicting cartilage biomechanical degradation from transcriptomic profiles: toward smart orthopedic device design.Front Bioeng Biotechnol202642147485PubTator, text miningPubMed
A kinase-related gene signature predicts prognosis and therapeutic response in head and neck squamous cell carcinoma.Oral Oncol202642090992PubTator, text miningPubMed
Innate immune profiling reveals a specific reduction of CD57+CD62L+CD161+ NK cells in CMV-positive males with hypertension.Front Immunol202642079601PubTator, text miningPubMed
Prognostic value of nuclear versus cytoplasmic cyclin D1 in human prostate cancer.Hum Pathol202642055230PubTator, text miningPubMed
Ustekinumab resistance in individuals with ulcerative colitis is associated with an alteration of a subset of proinflammatory mucosal regulatory T cells.Inflamm Bowel Dis202641984825PubTator, text miningPubMed
PIM1 Inhibition Alleviates Aspergillus fumigatus Keratitis by Regulating DDX41-Mediated STING Signaling Pathway.Invest Ophthalmol Vis Sci202641920144PubTator, text miningPubMed
Development of a progressive HIV-1-Like infection model in northern pig-tailed macaques using stHIV-1sv/G53D.Emerg Microbes Infect202641914615PubTator, text miningPubMed
Proteomic profiling and pathway analyses reveal molecular signatures and immune networks in pediatric sepsis.Inflamm Res202641896381PubTator, text miningPubMed
Quantitative HER2 tissue and plasma profiling predicts the activity of trastuzumab deruxtecan for breast cancer.NPJ Precis Oncol202641826432PubTator, text miningPubMed
Roles of RNA-binding proteins in macrophage function regulation and immunotherapy.Front Cell Dev Biol202641808933PubTator, text miningPubMed
Editorial: Novel biomarkers for early diagnosis involved in autoimmune and autoinflammatory diseases.Front Immunol202641798923PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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