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Gene · 11047

ADRM1: ADRM1 26S proteasome ubiquitin receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ADRM1: ADRM1 26S proteasome ubiquitin receptor. Genes, record 11047. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11047

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Gene

Symbol
ADRM1
HGNC
Name
ADRM1 26S proteasome ubiquitin receptor
HGNC
NCBI Gene ID
11047
NCBI Gene
HGNC ID
HGNC:15759
HGNC
Ensembl
ENSG00000130706
NCBI Gene
Aliases
ARM-1, ARM1, GP110, PSMD16, Rpn13
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16186Proteasomal ubiquitin receptor ADRM140721Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191422Q16186Espacenet
KR 1020250153662 A2025-10-273Q16186Espacenet
JP 2025517970 A2025-06-121422Q16186Espacenet
JP 2025062604 A2025-04-143156Q16186Espacenet
JP 2025062604 A2025-04-143157Q16186Espacenet
US 11708610 B22023-07-251014Q16186Espacenet
US 11702402 B22023-07-184Q16186Espacenet
US 11446398 B22022-09-203156Q16186Espacenet
US 11446398 B22022-09-203157Q16186Espacenet
JP 2022524081 A2022-04-27106127Q16186Espacenet

1 to 10 of 43

See all 43 patents

Drugs6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BORTEZOMIBCHEMBL32504126S proteasome inhibitorINHIBITORChEMBL
BORTEZOMIB D-MANNITOLCHEMBL531512226S proteasome inhibitorINHIBITORChEMBL
CARFILZOMIBCHEMBL45188726S proteasome inhibitorINHIBITORChEMBL
IXAZOMIBCHEMBL214129626S proteasome inhibitorINHIBITORChEMBL
IXAZOMIB CITRATECHEMBL354543226S proteasome inhibitorINHIBITORChEMBL
OPROZOMIBCHEMBL210388426S proteasome inhibitorINHIBITORChEMBL

Trials1,229

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07605416CARFILZOMIBPHASE2ClinicalTrials.gov
NCT07601100BORTEZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07600151BORTEZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07513129BORTEZOMIBPHASE1ClinicalTrials.gov
NCT07479979CARFILZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07464210BORTEZOMIBPHASE2ClinicalTrials.gov
NCT07463807CARFILZOMIBPHASE1/PHASE2ClinicalTrials.gov
NCT07428369BORTEZOMIBPHASE2/PHASE3ClinicalTrials.gov
NCT07391657BORTEZOMIBPHASE3ClinicalTrials.gov
NCT07391657CARFILZOMIBPHASE3ClinicalTrials.gov

1 to 10 of 1,229

See all 1,229 trials

NIH grants502

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleADRM1 papersNewest fiscal year
ZIABC011490Maintaining cell health by targeted protein degradation112025
P30CA006973Regional Oncology Research Center62025
P50CA098252SPORE in Cervical Cancer62025
P30CA016672Cancer Center Support Grant42025
P30CA042014Cancer Center Support Grant32025
R01GM065334Solution structure and dynamics of polyubiquitin chains32025
P01CA155258Integrative Oncogenomics of Multiple Myeloma22025
P01DA009158Endocannabinoid Active Sites as Therapeutic Targets22025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025
P30CA008748Cancer Center Support Grant22025

1 to 10 of 502Source NIH's project files

See all 502 nih grants

Papers608

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple-Negative Breast Cancer.Adv Sci (Weinh)202642565531PubTator, text miningPubMed
Ubiquitin-mediated degradation of RPN13 promotes porcine sperm capacitation and sperm-zona pellucida binding.Zygote202642554175PubTator, text miningPubMed
Substrate biasing in UCHL5 proteoforms.bioRxiv202642523381PubTator, text miningPubMed
Structures of dynamic interactors at native proteasomes by PhIX-MS and cryo-electron microscopy.Mol Cell202642476128PubTator, text miningPubMed
CDW19S coordinates phasic end processing via distinct enzymatic activities.Nucleic Acids Res202642406631PubTator, text miningPubMed
M6A-modified circArhgap26 attenuates cardiac ischemia‒reperfusion injury by suppressing plakophilin-1 palmitoylation.Signal Transduct Target Ther202641844577PubTator, text miningPubMed
Current research on adhesion regulating molecule 1: A Review.Biochem Biophys Res Commun202641825124PubTator, text miningPubMed
Repeat-rich RNA guides repetitive genomic elements into biomolecular condensates for heterochromatin organization and muscle integrity.Nucleic Acids Res202641797541PubTator, text miningPubMed
Systematic analysis of functional genetic and epigenetic variants in colorectal cancer.Sci Adv202641719390PubTator, text miningPubMed
Comprehensive analysis and experimental confirmation identify ADRM1 plays an oncogenic and immunosuppression role in KIRC.Biochem Biophys Res Commun202641406707PubTator, text miningPubMed

1 to 10 of 608

See all 608 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11047

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