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Gene · 1105

CHD1: chromodomain helicase DNA binding protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CHD1: chromodomain helicase DNA binding protein 1. Genes, record 1105. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1105

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Gene

Symbol
CHD1
HGNC
Name
chromodomain helicase DNA binding protein 1
HGNC
NCBI Gene ID
1105
NCBI Gene
HGNC ID
HGNC:1915
HGNC
Ensembl
ENSG00000153922
NCBI Gene
Aliases
CHD-1, PILBOS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O14646ATP-dependent chromatin remodeler CHD11,71018Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441317O14646Espacenet
EP 4641201 A22025-10-292787O14646Espacenet
JP 2025517969 A2025-06-122787O14646Espacenet
KR 1020240010752 A2024-01-24172O14646Espacenet
JP 2023165849 A2023-11-17172O14646Espacenet
US 11446398 B22022-09-2015232O14646Espacenet
US 11446398 B22022-09-2015236O14646Espacenet
JP 2022524081 A2022-04-27118203O14646Espacenet
JP 2022524081 A2022-04-27118207O14646Espacenet
US 10836808 B22020-11-17172O14646Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,560

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCHD1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant222025
P50CA097186The Pacific Northwest Prostate Cancer SPORE222025
P30CA016672Cancer Center Support Grant142025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer122025
P50CA186786Michigan Prostate SPORE 2025-2030112025
P30CA046934University of Colorado Cancer Center Support Grant92025
P30CA015704Cancer Center Support Grant82025
P50CA092629SPORE in Prostate Cancer72025
P30CA006973Regional Oncology Research Center62025
P30CA016086Cancer Center Support Grant62025

1 to 10 of 1,560Source NIH's project files

See all 1,560 nih grants

Papers1,932

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Chromatin remodeling coordinates chromosome compaction, synaptonemal complex architecture and meiotic crossing-over.Res Sq202642818913PubTator, text miningPubMed
Chromodomain helicase DNA-binding proteins and orofacial cleft.J Res Med Sci202642808081PubTator, text miningPubMed
De novo chromatin remodelling variants in sporadic Chiari 1 malformation.Brain202642640505PubTator, text miningPubMed
Early-Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection.MedComm (2020)202642488705PubTator, text miningPubMed
Divergent roles of SPOP and CHD1 in ACSL4 regulation reveal context-dependent vulnerabilities for targeting ferroptosis.Nat Commun202642380152PubTator, text miningPubMed
Free energy perturbation-assisted identification of checkpoint kinase 1 targeted small-molecule inhibitors for cancer therapy using AI- and physics-driven molecular design.Comput Biol Chem202642330574PubTator, text miningPubMed
A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force.ACS Nano202642324751PubTator, text miningPubMed
Role of CHD chromatin remodelers in heart development.World J Pediatr202642323439PubTator, text miningPubMed
L1CAM signaling through planar cell polarity drives SOX2 expression and lung adenocarcinoma metastasis.Nat Commun202642315504PubTator, text miningPubMed
Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity.Immunity202642285104PubTator, text miningPubMed

1 to 10 of 1,932

See all 1,932 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1105

GET https://conductscience.org/api/genes/v1/1105/patents?page=2