Gene · 1105
CHD1: chromodomain helicase DNA binding protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CHD1: chromodomain helicase DNA binding protein 1. Genes, record 1105. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1105
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O14646 | ATP-dependent chromatin remodeler CHD1 | 1,710 | 18 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 41317 | O14646 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2787 | O14646 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2787 | O14646 | Espacenet |
| KR 1020240010752 A | 2024-01-24 | 172 | O14646 | Espacenet |
| JP 2023165849 A | 2023-11-17 | 172 | O14646 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 15232 | O14646 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 15236 | O14646 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 118203 | O14646 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 118207 | O14646 | Espacenet |
| US 10836808 B2 | 2020-11-17 | 172 | O14646 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,560
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CHD1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 22 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 12 | 2025 |
| P50CA186786 | Michigan Prostate SPORE 2025-2030 | 11 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 9 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 8 | 2025 |
| P50CA092629 | SPORE in Prostate Cancer | 7 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 6 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 6 | 2025 |
1 to 10 of 1,560Source NIH's project files
See all 1,560 nih grantsPapers1,932
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Chromatin remodeling coordinates chromosome compaction, synaptonemal complex architecture and meiotic crossing-over. | Res Sq | 2026 | 42818913 | PubTator, text mining | PubMed |
| Chromodomain helicase DNA-binding proteins and orofacial cleft. | J Res Med Sci | 2026 | 42808081 | PubTator, text mining | PubMed |
| De novo chromatin remodelling variants in sporadic Chiari 1 malformation. | Brain | 2026 | 42640505 | PubTator, text mining | PubMed |
| Early-Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection. | MedComm (2020) | 2026 | 42488705 | PubTator, text mining | PubMed |
| Divergent roles of SPOP and CHD1 in ACSL4 regulation reveal context-dependent vulnerabilities for targeting ferroptosis. | Nat Commun | 2026 | 42380152 | PubTator, text mining | PubMed |
| Free energy perturbation-assisted identification of checkpoint kinase 1 targeted small-molecule inhibitors for cancer therapy using AI- and physics-driven molecular design. | Comput Biol Chem | 2026 | 42330574 | PubTator, text mining | PubMed |
| A Nanopore-Gated Subattoliter Silicon Nanocavity for Single-Molecule Trapping and Analysis without Applying an External Force. | ACS Nano | 2026 | 42324751 | PubTator, text mining | PubMed |
| Role of CHD chromatin remodelers in heart development. | World J Pediatr | 2026 | 42323439 | PubTator, text mining | PubMed |
| L1CAM signaling through planar cell polarity drives SOX2 expression and lung adenocarcinoma metastasis. | Nat Commun | 2026 | 42315504 | PubTator, text mining | PubMed |
| Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity. | Immunity | 2026 | 42285104 | PubTator, text mining | PubMed |
1 to 10 of 1,932
See all 1,932 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1105
GET https://conductscience.org/api/genes/v1/1105/patents?page=2