Gene · 11065
UBE2C: ubiquitin conjugating enzyme E2 C
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. UBE2C: ubiquitin conjugating enzyme E2 C. Genes, record 11065. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11065
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00762 | Ubiquitin-conjugating enzyme E2 C | 179 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 69052 | O00762 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5253 | O00762 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5253 | O00762 | Espacenet |
| JP 2023550743 A | 2023-12-05 | 69 | O00762 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 95121 | O00762 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 198092 | O00762 | Espacenet |
| US 10620209 B2 | 2020-04-14 | 7 | O00762 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 249487 | O00762 | Espacenet |
| JP 2018138044 A | 2018-09-06 | 117 | O00762 | Espacenet |
| US 10046010 B2 | 2018-08-14 | 117 | O00762 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,381
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | UBE2C papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 19 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 14 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 14 | 2025 |
| R35GM128855 | Spindle Assembly Checkpoint Silencing | 13 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 12 | 2025 |
| R01CA174777 | AR Gene Rearrangements and AR Signaling in Prostate Cancer | 10 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 9 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 7 | 2025 |
1 to 10 of 1,381Source NIH's project files
See all 1,381 nih grantsPapers2,651
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Identification of repositioned inhibitors of pan-cancer proteasomal target as potential anti-proliferative candidates using a computational therapeutics approach. | Biochem Biophys Res Commun | 2026 | 42800176 | PubTator, text mining | PubMed |
| EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy. | PLoS One | 2026 | 42691050 | PubTator, text mining | PubMed |
| In Vivo Multimodal Self-Immolative Prodrug Nanomicelle-Hydrogel Modulate Key Intratumoral and Metastatic Genomic Signaling Pathways in Pancreatic Cancer. | ACS Nano Med | 2026 | 42639086 | PubTator, text mining | PubMed |
| Multi-Omics Identification of UBE2C as a Prognostic Biomarker and Therapeutic Target Linked to Topotecan Sensitivity in Cervical Cancer. | Oncol Res | 2026 | 42630722 | PubTator, text mining | PubMed |
| Integrative single-nucleus transcriptomic analysis identifies UBE2C+ proliferative tumor cells and immune-stromal regulatory crosstalk in small cell lung cancer. | Front Immunol | 2026 | 42614523 | PubTator, text mining | PubMed |
| MiRNA-140-3p affects the proliferation and metastasis of osteosarcoma via the UBE2C/PI3K-Akt axis. | Front Oncol | 2026 | 42591213 | PubTator, text mining | PubMed |
| Mitotic Hub Gene Network in Colorectal Cancer: Integrated Transcriptomic, Protein-Level, and Clinical-Genomic Characterization of a Ten-Gene Signature. | Genes (Basel) | 2026 | 42510823 | PubTator, text mining | PubMed |
| UBE2C at the crossroads of cell cycle regulation and DNA damage response in cancer. | Cell Biol Toxicol | 2026 | 42477219 | PubTator, text mining | PubMed |
| Multi-state modeling associates proliferation genes with early estrogen receptor-positive breast cancer recurrence and survival. | Res Sq | 2026 | 42427829 | PubTator, text mining | PubMed |
| Single-cell and bulk transcriptomics identify senescence-related EMT transcriptional programs and a prognostic framework in pancreatic ductal adenocarcinoma. | BMC Gastroenterol | 2026 | 42420840 | PubTator, text mining | PubMed |
1 to 10 of 2,651
See all 2,651 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/11065
GET https://conductscience.org/api/genes/v1/11065/patents?page=2