ConductScience.org, home

Gene · 11065

UBE2C: ubiquitin conjugating enzyme E2 C

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. UBE2C: ubiquitin conjugating enzyme E2 C. Genes, record 11065. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11065

On this page

Gene

Symbol
UBE2C
HGNC
Name
ubiquitin conjugating enzyme E2 C
HGNC
NCBI Gene ID
11065
NCBI Gene
HGNC ID
HGNC:15937
HGNC
Ensembl
ENSG00000175063
NCBI Gene
Aliases
UBCH10, dJ447F3.2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O00762Ubiquitin-conjugating enzyme E2 C1799Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1469052O00762Espacenet
EP 4641202 A22025-10-295253O00762Espacenet
KR 1020250017231 A2025-02-045253O00762Espacenet
JP 2023550743 A2023-12-0569O00762Espacenet
US 11446398 B22022-09-2095121O00762Espacenet
JP 2022524081 A2022-04-27198092O00762Espacenet
US 10620209 B22020-04-147O00762Espacenet
JP 2019054813 A2019-04-11249487O00762Espacenet
JP 2018138044 A2018-09-06117O00762Espacenet
US 10046010 B22018-08-14117O00762Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,381

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleUBE2C papersNewest fiscal year
P30CA016672Cancer Center Support Grant192025
P30CA016086Cancer Center Support Grant142025
P30CA021765Cancer Center Support Grant (CCSG)142025
R35GM128855Spindle Assembly Checkpoint Silencing132025
P50CA097186The Pacific Northwest Prostate Cancer SPORE122025
R01CA174777AR Gene Rearrangements and AR Signaling in Prostate Cancer102025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer92025
P30CA006973Regional Oncology Research Center72025
P30CA008748Cancer Center Support Grant72025
P30CA093373Cancer Center Support Grant P3072025

1 to 10 of 1,381Source NIH's project files

See all 1,381 nih grants

Papers2,651

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of repositioned inhibitors of pan-cancer proteasomal target as potential anti-proliferative candidates using a computational therapeutics approach.Biochem Biophys Res Commun202642800176PubTator, text miningPubMed
EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy.PLoS One202642691050PubTator, text miningPubMed
In Vivo Multimodal Self-Immolative Prodrug Nanomicelle-Hydrogel Modulate Key Intratumoral and Metastatic Genomic Signaling Pathways in Pancreatic Cancer.ACS Nano Med202642639086PubTator, text miningPubMed
Multi-Omics Identification of UBE2C as a Prognostic Biomarker and Therapeutic Target Linked to Topotecan Sensitivity in Cervical Cancer.Oncol Res202642630722PubTator, text miningPubMed
Integrative single-nucleus transcriptomic analysis identifies UBE2C+ proliferative tumor cells and immune-stromal regulatory crosstalk in small cell lung cancer.Front Immunol202642614523PubTator, text miningPubMed
MiRNA-140-3p affects the proliferation and metastasis of osteosarcoma via the UBE2C/PI3K-Akt axis.Front Oncol202642591213PubTator, text miningPubMed
Mitotic Hub Gene Network in Colorectal Cancer: Integrated Transcriptomic, Protein-Level, and Clinical-Genomic Characterization of a Ten-Gene Signature.Genes (Basel)202642510823PubTator, text miningPubMed
UBE2C at the crossroads of cell cycle regulation and DNA damage response in cancer.Cell Biol Toxicol202642477219PubTator, text miningPubMed
Multi-state modeling associates proliferation genes with early estrogen receptor-positive breast cancer recurrence and survival.Res Sq202642427829PubTator, text miningPubMed
Single-cell and bulk transcriptomics identify senescence-related EMT transcriptional programs and a prognostic framework in pancreatic ductal adenocarcinoma.BMC Gastroenterol202642420840PubTator, text miningPubMed

1 to 10 of 2,651

See all 2,651 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11065

GET https://conductscience.org/api/genes/v1/11065/patents?page=2