Gene · 11073
Papers1,761
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
1 to 20 of 1,761
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| DDIAS shields vulnerable single-stranded DNA to direct neurogenesis and protect cancer cells. | Mol Cell | 2026 | 42822412 | PubTator, text mining | PubMed |
| MCPH1 and DNA Damage Response Pathway Genes as Candidate Susceptibility Loci in Hereditary Breast Cancer. | Diagnostics (Basel) | 2026 | 42793752 | PubTator, text mining | PubMed |
| Mechanistic insights into phosphorylation-driven activation and therapeutic inhibition of human ATR-ATRIP. | Nat Struct Mol Biol | 2026 | 42754753 | PubTator, text mining | PubMed |
| SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA-PKcs/CHK1 replicative checkpoint to inhibit cell growth in non-small cell lung cancer. | Mol Oncol | 2026 | 42751865 | PubTator, text mining | PubMed |
| The KEAP1-NFE2L2/NRF2 Axis in Non-Small Cell Lung Cancer Radioresistance: Redox Homeostasis and Emerging DNA Damage Response Mechanisms. | Cancer Manag Res | 2026 | 42708106 | PubTator, text mining | PubMed |
| Dynamic chromatin tethering of MDC1 regulates genome stability. | Nucleic Acids Res | 2026 | 42703974 | PubTator, text mining | PubMed |
| DNA end-resection is stimulated by an interaction between BRCA1 exon 11 and TOPBP1. | EMBO Rep | 2026 | 42661062 | PubTator, text mining | PubMed |
| DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development. | Cell | 2026 | 42636811 | PubTator, text mining | PubMed |
| Mitotic single-stranded DNA suppression by DDIAS. | Mol Cell | 2026 | 42636809 | PubTator, text mining | PubMed |
| Development of a structurally distinct TopBP1 inhibitor that enhances PARP blockade and reverses osimertinib resistance. | Sci Adv | 2026 | 42555732 | PubTator, text mining | PubMed |
| CIP2A-TOPBP1 complex and PP2A dynamically regulate Polθ recruitment and phosphorylation at mitotic DNA double-strand breaks. | Proc Natl Acad Sci U S A | 2026 | 42546199 | PubTator, text mining | PubMed |
| Targeting RPRD1B overcomes chemoresistance in gastric cancer by suppressing the TOPBP1-mediated DNA damage repair pathway. | Cell Oncol (Dordr) | 2026 | 42542502 | PubTator, text mining | PubMed |
| New Roles of Chk1 in Spindle Formation and Genome Integrity. | Biology (Basel) | 2026 | 42510653 | PubTator, text mining | PubMed |
| Structural mechanism of TOPBP1 activating the ATR-ATRIP replication checkpoint kinase. | Nat Struct Mol Biol | 2026 | 42493622 | PubTator, text mining | PubMed |
| CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation. | Bone Joint Res | 2026 | 42486479 | PubTator, text mining | PubMed |
| Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH). | Curr Issues Mol Biol | 2026 | 42353577 | PubTator, text mining | PubMed |
| CRISPR/Cas9-mediated knockout of TopBP1 shifts the Bax/Bcl-2 balance toward apoptosis in MCF7 breast cancer cells. | Mol Biol Rep | 2026 | 42283883 | PubTator, text mining | PubMed |
| Structural mechanism of TopBP1 recognizing phosphorylated HTATSF1 in homologous recombination repair. | Biochem Biophys Res Commun | 2026 | 42251821 | PubTator, text mining | PubMed |
| Fragment-based discovery of TopBP1 inhibitors integrated with AI-driven molecular docking. | Magn Reson Lett | 2026 | 42221021 | PubTator, text mining | PubMed |
| Treacle-dependent TOPBP1 condensation regulates the nucleolar DNA damage response. | Nucleic Acids Res | 2026 | 42152682 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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