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Gene · 11076

TPPP: tubulin polymerization promoting protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TPPP: tubulin polymerization promoting protein. Genes, record 11076. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11076

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Gene

Symbol
TPPP
HGNC
Name
tubulin polymerization promoting protein
HGNC
NCBI Gene ID
11076
NCBI Gene
HGNC ID
HGNC:24164
HGNC
Ensembl
ENSG00000171368
NCBI Gene
Aliases
TPPP/p25, TPPP1, p24, p25, p25alpha
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O94811Tubulin polymerization-promoting protein2193Ensembl, GeneID, HGNC

Source UniProt

Patents20

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468505O94811Espacenet
JP 2025032204 A2025-03-1137530O94811Espacenet
EP 4461818 A22024-11-1337530O94811Espacenet
JP 2023058610 A2023-04-2537530O94811Espacenet
US 11446398 B22022-09-2093440O94811Espacenet
JP 2022524081 A2022-04-27196411O94811Espacenet
US 11078247 B22021-08-0311908O94811Espacenet
JP 2020508652 A2020-03-2637530O94811Espacenet
JP 2019054813 A2019-04-11248940O94811Espacenet
JP 2017121241 A2017-07-13248940O94811Espacenet

1 to 10 of 20

See all 20 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants855

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTPPP papersNewest fiscal year
R28AA012725Brain Tissue Resource Center for Alcohol Research62025
P30CA008748Cancer Center Support Grant32025
R01ES013744Stress-Air Pollution Interactions and Adolescent Neurobehavior32025
UL1TR001863Yale Clinical and Translational Science Award32025
P30CA068485Cancer Center Support Grant22025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital22025
P30DK048520Colorado Nutrition Obesity Research Center22025
P30DK063491Diabetes Research Center (DRC)22025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)22025
P30ES023515Mount Sinai Center for Health and Environment Across the LifeSpan (HEALS)22025

1 to 10 of 855Source NIH's project files

See all 855 nih grants

Papers1,727

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Ringer Loss in Drosophila Uncovers Mitochondrial Complex I Deficits Relevant to Human Parkinson's Disease.bioRxiv202642619695PubTator, text miningPubMed
TPPP/p25 amyloid seeding activity as a specific biomarker for multiple system atrophy.Cell202642190663PubTator, text miningPubMed
Antiproliferative Activity and Acute Toxicity of α,β-Bis(diphenylphosphine Oxide)ethanes Obtained by Bisphosphorylation of Acetylenes: Electrosynthesis Under Mild Conditions Versus Improved Superbasic Medium Synthesis.
ChemMedChem202642035247PubTator, text miningPubMed
Human receptive endometrial assembloid for deciphering the implantation window.Elife202641920166PubTator, text miningPubMed
Maternal supplementation of vitamin B12 in predominantly vegetarian pregnant women improves their vitamin B12 status and the neurodevelopment of their infants: the MATCOBIND multicentric double-blind randomised control trial.
BMJ Paediatr Open202641850742PubTator, text miningPubMed
Manufacturing Silk Fibroin Hollow Nanoyarns as Fundamental Units for Advanced Medical Textiles.ACS Appl Mater Interfaces202641844170PubTator, text miningPubMed
The dual role of BRD9 in cancer: Mechanistic insights and therapeutic prospects.iScience202641797932PubTator, text miningPubMed
[Correlation of occlusion pressure with sedation in non-neurocritical patients].Rev Med Inst Mex Seguro Soc202641774530PubTator, text miningPubMed
Reliability of a pressure pain threshold protocol: secondary analysis of a longitudinal trial with cluster randomization.PeerJ202641769391PubTator, text miningPubMed
Stress-induced epigenome changes as a risk factor in the onset of mental disorders.Front Psychiatry202641756569PubTator, text miningPubMed

1 to 10 of 1,727

See all 1,727 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11076

GET https://conductscience.org/api/genes/v1/11076/patents