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CHD4: chromodomain helicase DNA binding protein 4
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Gene · 1108

Papers2,308

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,308

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TitleJournalYearPMIDFound bySource
Chromodomain helicase DNA-binding proteins and orofacial cleft.J Res Med Sci202642808081PubTator, text miningPubMed
De novo chromatin remodelling variants in sporadic Chiari 1 malformation.Brain202642640505PubTator, text miningPubMed
Targeting HDAC and proteostasis to eradicate quiescent cancer cells.Cancer Gene Ther202642595792PubTator, text miningPubMed
Deubiquitinase USP22 maintains B cell homeostasis through the CHD4-CD19 signaling axis and is dysregulated in Kawasaki disease.Sci Bull (Beijing)202642586813PubTator, text miningPubMed
Motif-Cluster: Motif driven prioritization of transcription factor binding clusters.PLoS Comput Biol202642555666PubTator, text miningPubMed
Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells.bioRxiv202642539289PubTator, text miningPubMed
Genotypic and Phenotypic Profile of 50 Cases With Chromatin Remodeling Complexes-Related Neurological Disorders.CNS Neurosci Ther202642528014PubTator, text miningPubMed
Somatic Cancer Driver Mutation Analysis in Endometriosis with Tumor-like Presentations: A Case Series Study.Biomedicines202642512109PubTator, text miningPubMed
Exploring Targets for Heart Failure Using Mendelian Randomization, Colocalization, Summary Data-based Mendelian Randomization, and Drug Prediction.J Vis Exp202642507612PubTator, text miningPubMed
CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes.Cancer Cell202642468521PubTator, text miningPubMed
ADNP Functions During Early Brain Development and Their Relevance to ASD and ADNP Syndrome.Int J Mol Sci202642450350PubTator, text miningPubMed
Co-Phosphoregulatory Network Underlying Functional Coherence of TLK1 and TLK2 Kinase Paralogs.Int J Mol Sci202642353285PubTator, text miningPubMed
Re: "Clinical Insights From a Case of Sifrim-Hitz-Weiss Syndrome With a CHD4 Variant: Expanding the Phenotypic Spectrum and Its Response to Growth Hormone Therapy".Am J Med Genet A202642338269PubTator, text miningPubMed
Transcriptomic profiling of epigenetic regulators and metabolic reprogramming in human cholangiocarcinoma.Front Cell Dev Biol202642326014PubTator, text miningPubMed
Role of CHD chromatin remodelers in heart development.World J Pediatr202642323439PubTator, text miningPubMed
Triple metachronous primary brain tumors: sequential occurrence of astrocytoma, atypical meningioma, and high-grade glioma without radiotherapy exposure. Illustrative case.J Neurosurg Case Lessons202642296557PubTator, text miningPubMed
Swine acute diarrhea syndrome coronavirus nsp5 induces apoptosis by targeting GATA zinc finger domain-containing protein 2A (GATAD2A/p66α).mBio202642294686PubTator, text miningPubMed
Macrocycle screening against the C-terminal region of CHD4 uncovers its role as an interaction hub in the formation of the nucleosome remodeling and deacetylase complex.bioRxiv202642282813PubTator, text miningPubMed
Modeling Therapeutic Targets: β-Globin Disorders and Beyond.Adv Exp Med Biol202642178475PubTator, text miningPubMed
CHD4 is a copper sensor linking chromatin remodeling to cuproptosis.Free Radic Biol Med202642176908PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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