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Gene · 11091

Papers2,554

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
PRMT5 promotes ferroptosis in cisplatin-induced acute kidney injury through WDR5/ACSL4 pathway.Redox Biol202642826479PubTator, text miningPubMed
Pro-GAT: Reconnecting Fragmented PROTACs Using Graph Attention Transformer.J Chem Inf Model202642734562PubTator, text miningPubMed
Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state.Mol Cell202642673957PubTator, text miningPubMed
The ISL1-WDR5-H3K4me3-STC1 axis attenuates cerebral ischemia-reperfusion injury.Int Immunopharmacol202642497659PubTator, text miningPubMed
Site-Specific Hydrogen-Deuterium Exchange Mass Spectrometry for Deep Explorations of Dynamic Shifts in Protein-Drug Interactions.J Am Chem Soc202642420201PubTator, text miningPubMed
Role of thromboelastography in risk stratifying patients with traumatic brain injury on prehospital antiplatelet agents.Trauma Surg Acute Care Open202642344540PubTator, text miningPubMed
Epigenetic compartmentalization of mitotic chromosomes by phase-separation-driven repulsion between WDR5 and the chromosomal passenger complex.Nat Commun202642303627PubTator, text miningPubMed
Retrospective Validation of the Brain Injury Guidelines at a Single Community Institution.Cureus202642255828PubTator, text miningPubMed
Promiscuous RNA binding by WDR5 remodels the KMT2A (MLL1) histone methyltransferase complex to an inactive state.bioRxiv202642239275PubTator, text miningPubMed
Targeting the MYCN interaction network in neuroblastoma.Biosci Rep202642233780PubTator, text miningPubMed
Linker-Driven Sampling of PROTAC-Induced Ternary Complexes.J Med Chem202642233498PubTator, text miningPubMed
Molecular mechanisms of the MLL4 complex in H3K4 methylation and p53-dependent transcription activation.Mol Cell202642214331PubTator, text miningPubMed
Decoding WDR5-Mediated Interactions in Gliomas: Implications for Targeted Therapy.Med Res Rev202642131930PubTator, text miningPubMed
Novel regulatory SNPs that can be activated due to metformin treatment may orchestrate liver gluconeogenesis and add to the variability in AMPK-dependent mechanisms of metformin response.Vavilovskii Zhurnal Genet Selektsii202642111789PubTator, text miningPubMed
Development and characterization of triazole-based WDR5 inhibitors for the treatment of glioblastoma.JCI Insight202642084925PubTator, text miningPubMed
RYBP regulates selective genomic binding of TrxG and PcG components in embryonic stem cell fate control.EMBO J202642049912PubTator, text miningPubMed
Water-mediated compensation preserves WIN motif binding in WDR5 aromatic mutants.Biochem Biophys Res Commun202642048953PubTator, text miningPubMed
ChemScreener: an active learning enabled hit discovery workflow with WDR5 inhibitor case study.J Cheminform202642010453PubTator, text miningPubMed
Structure-based design of the approved drug zafirlukast identifies HLC40 as a potent WDR5 WIN-site inhibitor with antitumor efficacy.Bioorg Chem202642001591PubTator, text miningPubMed
Massive barcode-free chemical screenings enable the discovery of bioactive macrocycles with passive membrane permeability.Nat Commun202641963347PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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