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ADAMTS5: ADAM metallopeptidase with thrombospondin type 1 motif 5
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Gene · 11096

Papers3,260

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 3,260

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TitleJournalYearPMIDFound bySource
Inhibition of the Metalloproteinase ADAMTS5 Suppresses Colorectal Cancer Metastasis via the PEDF/Wnt/β-Catenin Pathway.Cancer Med202642473035PubTator, text miningPubMed
LncRNA TTN-AS1 targets miR-520d-5p to regulate the function of synovial fibroblasts and influences the progression of osteoarthritis.BMC Musculoskelet Disord202642464195PubTator, text miningPubMed
Chondroprotective Effects of Enzyme-Treated Extract from Cervus elaphus L. in a Rat Model of Osteoarthritis.Int J Mol Sci202642450056PubTator, text miningPubMed
Effects of high-molecular-weight hyaluronic acid on inflammatory and matrix-associated responses in a chondrocyte-osteoclast co-culture model.J Orthop Surg Res202642443940PubTator, text miningPubMed
A selective low-dose cisplatin strategy enabled by melatonin and cannabinoids for targeting osteosarcoma and chondrosarcoma.Naunyn Schmiedebergs Arch Pharmacol202642362763PubTator, text miningPubMed
YAP1 Knockdown Reduces IL-1β-Induced Human Chondrocyte Inflammation and Promotes Human MSC Chondrogenesis.Pharmaceuticals (Basel)202642356478PubTator, text miningPubMed
miR-584-5p alleviates osteoarthritis by targeting HIF1A to regulate chondrocyte function and extracellular matrix metabolism.J Orthop Surg Res202642316286PubTator, text miningPubMed
Integrating network toxicology, molecular docking and experimental validation reveals potential mechanisms of DEHP in osteoarthritis.Exp Gerontol202642269982PubTator, text miningPubMed
Comparative Analysis of Dual-miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair.JOR Spine202642253284PubTator, text miningPubMed
FGF19 promotes cartilage destruction in the progress of temporomandibular joint osteoarthritis.Cell Tissue Res202642247043PubTator, text miningPubMed
Integrated Molecular Docking and Network-Based Analysis Reveals Multitarget Interaction Patterns of Nutraceutical Compounds in Intervertebral Disc Degeneration.Biomedicines202642193310PubTator, text miningPubMed
A multi-switch mechanism underlying mechanical force regulation of aggrecan degradation in osteoarthritic cartilage.Osteoarthritis Cartilage202642176879PubTator, text miningPubMed
Characterization of Cancer Hallmark Enhancer RNA Uncovers Novel Strategies for Precision Oncology.Genomics Proteomics Bioinformatics202642143621PubTator, text miningPubMed
A multiscale modeling approach to study the role of mechanics and inflammation in the pathophysiology of articular cartilage.Comput Biol Med202642119318PubTator, text miningPubMed
The common pathological network of inflammation, extracellular matrix imbalance, and senescence in intervertebral disc degeneration and osteoarthritis.Mol Biol Rep202642113297PubTator, text miningPubMed
Smart Functionalization of Acupuncture Needle Enables Molecular Subtyping and Personalized Treatment of Osteoarthritis.ACS Biomater Sci Eng202642082135PubTator, text miningPubMed
PLGA Nanoparticle-Mediated Sustained Release of Fisetin for Intra-Articular Therapy of Temporomandibular Joint Osteoarthritis.Int J Mol Sci202642074255PubTator, text miningPubMed
Advanced treatment for articular cartilage lesions: Development of an injectable glucosinolate-releasing hyaluronic acid.Int J Biol Macromol202642034134PubTator, text miningPubMed
Triamcinolone Acetonide Is Not Harmful to Healthy and Osteoarthritic Human Knee Cartilage.Am J Sports Med202642011976PubTator, text miningPubMed
FGF8 accelerates osteoarthritic chondrocyte hypertrophy by JunB-mediated cytokine perturbation.Life Sci202641990914PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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