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Gene · 1114

CHGB: chromogranin B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CHGB: chromogranin B. Genes, record 1114. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1114

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Gene

Symbol
CHGB
HGNC
Name
chromogranin B
HGNC
NCBI Gene ID
1114
NCBI Gene
HGNC ID
HGNC:1930
HGNC
Ensembl
ENSG00000089199
NCBI Gene
Aliases
SCG1, SgI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P05060Secretogranin-16770Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441355P05060Espacenet
EP 4650780 A22025-11-1910108P05060Espacenet
EP 4641201 A22025-10-2910404P05060Espacenet
JP 2025147176 A2025-10-062767P05060Espacenet
JP 2025529142 A2025-09-045857P05060Espacenet
US 12371689 B22025-07-295857P05060Espacenet
JP 2025517969 A2025-06-1210404P05060Espacenet
JP 2025517970 A2025-06-1210108P05060Espacenet
JP 2025032204 A2025-03-1126290P05060Espacenet
JP 2025028160 A2025-02-282767P05060Espacenet

1 to 10 of 34

See all 34 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants880

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCHGB papersNewest fiscal year
P50CA097186The Pacific Northwest Prostate Cancer SPORE132025
P30CA008748Cancer Center Support Grant92025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer62025
P50CA186786Michigan Prostate SPORE 2025-203052025
P30DK034987Center for Gastrointestinal Biology and Disease42025
U24CA213274Coordinating center for the NCI small cell lung cancer research consortium42025
P30CA006973Regional Oncology Research Center32025
P30CA015704Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant32025

1 to 10 of 880Source NIH's project files

See all 880 nih grants

Papers1,390

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Chromogranin B acts as a neuronal paracrine factor to trigger oligodendrocyte apoptosis.PLoS One202642766543PubTator, text miningPubMed
Proteomic analysis reveals a metabolic switch and cellular remodelling in pancreatic-like cell spheroids cocultured with hepatocyte-like cells using an interconnected liver-pancreas-on-chip system.Mol Omics202642644453PubTator, text miningPubMed
Expression Profiling of Immune-Related Genes in Different Samples from Patients with Endometriosis Revealed Upregulation of THBS1, CHGB and CYR61.Int J Mol Sci202642589547PubTator, text miningPubMed
Myasthenia thymus reprograms class-switched B cells into BAFF-dependent survivors.Sci Adv202642585334PubTator, text miningPubMed
Large-scale transcriptome analysis reveals KIF20A as a novel indicator of cisplatin resistance in high-grade serous ovarian cancer.J Ovarian Res202642426841PubTator, text miningPubMed
Protein Predictors of Worsening Cerebral Edema in Traumatic Brain Injury in Critically Ill Patients.bioRxiv202642244667PubTator, text miningPubMed
Prognostic biomarkers and Hedgehog pathway activation in early prostate cancer neuroendocrine differentiation via spatial profiling.NPJ Precis Oncol202642092131PubTator, text miningPubMed
Transcriptome predictors of second breast events in ductal carcinoma in situ: a case‒control study including Black and White women.Breast Cancer Res202642087182PubTator, text miningPubMed
Identification of key genes and immune mechanisms in atrial fibrillation: An observational bioinformatics and single-cell transcriptome study.Medicine (Baltimore)202642071886PubTator, text miningPubMed
Human Meningiomas Reveal No Evidence of Neuroendocrine Differentiation.APMIS202641769706PubTator, text miningPubMed

1 to 10 of 1,390

See all 1,390 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1114

GET https://conductscience.org/api/genes/v1/1114/patents?page=2