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Gene · 11140

CDC37: cell division cycle 37, HSP90 cochaperone

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDC37: cell division cycle 37, HSP90 cochaperone. Genes, record 11140. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11140

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Gene

Symbol
CDC37
HGNC
Name
cell division cycle 37, HSP90 cochaperone
HGNC
NCBI Gene ID
11140
NCBI Gene
HGNC ID
HGNC:1735
HGNC
Ensembl
ENSG00000105401
NCBI Gene
Aliases
P50CDC37
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16543Hsp90 co-chaperone Cdc3737819Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19533Q16543Espacenet
JP 2025517970 A2025-06-12533Q16543Espacenet
US 12297234 B22025-05-1345Q16543Espacenet
EP 4484957 A12025-01-0158Q16543Espacenet
EP 4426882 A12024-09-1176Q16543Espacenet
US 11993635 B22024-05-2845Q16543Espacenet
US 11860162 B22024-01-021298Q16543Espacenet
KR 1020230155484 A2023-11-1016Q16543Espacenet
KR 1020230155484 A2023-11-1060Q16543Espacenet
EP 4266058 A22023-10-2545Q16543Espacenet

1 to 10 of 58

See all 58 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,102

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDC37 papersNewest fiscal year
P30CA008748Cancer Center Support Grant222025
ZIABC011032Post-translational modifications of Hsp90222025
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction212025
R01NS073899The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function102025
P30CA076292Moffitt Cancer Center Support Grant72025
R01NS059690Molecular Chaperones and Small Molecules72025
R35GM139584Regulatory mechanisms of the Hsp90 chaperone machinery72025
P30CA016672Cancer Center Support Grant52025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202852025
R35GM122523Molecular Mechanisms of Cell Signaling52025

1 to 10 of 1,102Source NIH's project files

See all 1,102 nih grants

Papers1,640

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Citrullination-associated transcriptional states identify a non-canonical invasive program in malignant epithelial cells and correlate with SPP1-CD44 immune microenvironment niches in thyroid cancer.Transl Oncol202642556131PubTator, text miningPubMed
Celastrol at the obesity-cancer interface: critical appraisal of molecular mechanisms, preclinical evidence, and translational barriers.Mol Biol Rep202642467316PubTator, text miningPubMed
Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer's Disease.Drug Des Devel Ther202642221352PubTator, text miningPubMed
Hsp70/Hsp90 Organizing Protein (HOP) Maintains CRAF Kinase Activity and Regulates MAPK Signaling by Enhancing Hsp90-CRAF Association.Mol Cell Biol202641982048PubTator, text miningPubMed
ncRNA-Mediated Upregulation of AURKA Promotes Hepatocellular Carcinoma Progression and Alters the Immune Microenvironment.Bioinform Biol Insights202641908244PubTator, text miningPubMed
Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target.Aging Cell202641786630PubTator, text miningPubMed
Network pharmacology, machine learning, and experiments uncover β-sitosterol targeting HSP90AA1 in medicinal-edible black soybean against aging.Front Med (Lausanne)202641778031PubTator, text miningPubMed
Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential.Front Aging Neurosci202641767843PubTator, text miningPubMed
Natural Product Modulators of Protein-Protein Interactions: A Comprehensive Review.Phytochem Anal202641677319PubTator, text miningPubMed
Region-resolved proteomic map of the human brain: functional interconnections and neurological implications.Signal Transduct Target Ther202641633974PubTator, text miningPubMed

1 to 10 of 1,640

See all 1,640 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11140

GET https://conductscience.org/api/genes/v1/11140/patents?page=2