Gene · 11140
CDC37: cell division cycle 37, HSP90 cochaperone
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDC37: cell division cycle 37, HSP90 cochaperone. Genes, record 11140. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11140
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16543 | Hsp90 co-chaperone Cdc37 | 378 | 19 | Ensembl, GeneID, HGNC |
Source UniProt
Patents58
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 533 | Q16543 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 533 | Q16543 | Espacenet |
| US 12297234 B2 | 2025-05-13 | 45 | Q16543 | Espacenet |
| EP 4484957 A1 | 2025-01-01 | 58 | Q16543 | Espacenet |
| EP 4426882 A1 | 2024-09-11 | 76 | Q16543 | Espacenet |
| US 11993635 B2 | 2024-05-28 | 45 | Q16543 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1298 | Q16543 | Espacenet |
| KR 1020230155484 A | 2023-11-10 | 16 | Q16543 | Espacenet |
| KR 1020230155484 A | 2023-11-10 | 60 | Q16543 | Espacenet |
| EP 4266058 A2 | 2023-10-25 | 45 | Q16543 | Espacenet |
1 to 10 of 58
See all 58 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,102
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDC37 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 22 | 2025 |
| ZIABC011032 | Post-translational modifications of Hsp90 | 22 | 2025 |
| ZIASC010074 | HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction | 21 | 2025 |
| R01NS073899 | The hsp90 Cochaperone FKBP51 Regulates tau Structure and Function | 10 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 7 | 2025 |
| R01NS059690 | Molecular Chaperones and Small Molecules | 7 | 2025 |
| R35GM139584 | Regulatory mechanisms of the Hsp90 chaperone machinery | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 5 | 2025 |
| R35GM122523 | Molecular Mechanisms of Cell Signaling | 5 | 2025 |
1 to 10 of 1,102Source NIH's project files
See all 1,102 nih grantsPapers1,640
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Citrullination-associated transcriptional states identify a non-canonical invasive program in malignant epithelial cells and correlate with SPP1-CD44 immune microenvironment niches in thyroid cancer. | Transl Oncol | 2026 | 42556131 | PubTator, text mining | PubMed |
| Celastrol at the obesity-cancer interface: critical appraisal of molecular mechanisms, preclinical evidence, and translational barriers. | Mol Biol Rep | 2026 | 42467316 | PubTator, text mining | PubMed |
| Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer's Disease. | Drug Des Devel Ther | 2026 | 42221352 | PubTator, text mining | PubMed |
| Hsp70/Hsp90 Organizing Protein (HOP) Maintains CRAF Kinase Activity and Regulates MAPK Signaling by Enhancing Hsp90-CRAF Association. | Mol Cell Biol | 2026 | 41982048 | PubTator, text mining | PubMed |
| ncRNA-Mediated Upregulation of AURKA Promotes Hepatocellular Carcinoma Progression and Alters the Immune Microenvironment. | Bioinform Biol Insights | 2026 | 41908244 | PubTator, text mining | PubMed |
| Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target. | Aging Cell | 2026 | 41786630 | PubTator, text mining | PubMed |
| Network pharmacology, machine learning, and experiments uncover β-sitosterol targeting HSP90AA1 in medicinal-edible black soybean against aging. | Front Med (Lausanne) | 2026 | 41778031 | PubTator, text mining | PubMed |
| Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential. | Front Aging Neurosci | 2026 | 41767843 | PubTator, text mining | PubMed |
| Natural Product Modulators of Protein-Protein Interactions: A Comprehensive Review. | Phytochem Anal | 2026 | 41677319 | PubTator, text mining | PubMed |
| Region-resolved proteomic map of the human brain: functional interconnections and neurological implications. | Signal Transduct Target Ther | 2026 | 41633974 | PubTator, text mining | PubMed |
1 to 10 of 1,640
See all 1,640 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/11140
GET https://conductscience.org/api/genes/v1/11140/patents?page=2