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CHKA: choline kinase alpha

1 protein, 16 patents, 2 drugs, 0 trials, 2,227 NIH grants and 4,616 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCHKAHGNC
Namecholine kinase alphaHGNC
NCBI Gene ID1119NCBI Gene
HGNC IDHGNC:1937HGNC
EnsemblENSG00000110721NCBI Gene
AliasesCHK, CK, CKI, EK, NEDMIMSNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35790Choline kinase alpha45726Ensembl, GeneID, HGNCUniProt

Patents 16

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441199P35790Espacenet
EP 4650780 A22025-11-192509P35790Espacenet
JP 2025517970 A2025-06-122509P35790Espacenet
US 11446398 B22022-09-2014993P35790Espacenet
JP 2022524081 A2022-04-27117964P35790Espacenet
WO 2020043864 A12020-03-05457P35790Espacenet
JP 2019054813 A2019-04-11221634P35790Espacenet
JP 2017121241 A2017-07-13221634P35790Espacenet
US 9381172 B22016-07-051P35790Espacenet
JP 2015516143 A2015-06-08221634P35790Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RSM-932ACHEMBL192986Choline kinase alpha inhibitorINHIBITORChEMBL
RSM-932A CATIONCHEMBL1181829Choline kinase alpha inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2227

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant322,025NIH's project files
P30CA006973Regional Oncology Research Center202,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)72,025NIH's project files
P30CA033572Cancer Center Support Grant52,025NIH's project files
P30CA047904Cancer Center Support Grant52,025NIH's project files
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health52,025NIH's project files
P20GM103434West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)42,025NIH's project files
P30CA006927Comprehensive Cancer Center Program at Fox Chase42,025NIH's project files
P30CA016087Cancer Center Support Grant42,025NIH's project files

Papers 4616

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822277PubTator, text miningPubMed
42810220PubTator, text miningPubMed
42777803PubTator, text miningPubMed
42731482PubTator, text miningPubMed
42729262PubTator, text miningPubMed
42727664PubTator, text miningPubMed
42687344PubTator, text miningPubMed
42570027PubTator, text miningPubMed
42509416PubTator, text miningPubMed
42446981PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license