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Gene · 11197

WIF1: Wnt inhibitory factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. WIF1: Wnt inhibitory factor 1. Genes, record 11197. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11197

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Gene

Symbol
WIF1
HGNC
Name
Wnt inhibitory factor 1
HGNC
NCBI Gene ID
11197
NCBI Gene
HGNC ID
HGNC:18081
HGNC
Ensembl
ENSG00000156076
NCBI Gene
Aliases
WIF-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y5W5Wnt inhibitory factor 13795Ensembl, GeneID, HGNC

Source UniProt

Patents275

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193294Q9Y5W5Espacenet
EP 4641201 A22025-10-292869Q9Y5W5Espacenet
JP 2025147176 A2025-10-0614257Q9Y5W5Espacenet
JP 2025529142 A2025-09-048074Q9Y5W5Espacenet
US 12371689 B22025-07-298074Q9Y5W5Espacenet
JP 2025517969 A2025-06-122869Q9Y5W5Espacenet
JP 2025517970 A2025-06-123294Q9Y5W5Espacenet
JP 2025032204 A2025-03-1138177Q9Y5W5Espacenet
JP 2025028160 A2025-02-2814257Q9Y5W5Espacenet
KR 1020250010750 A2025-01-2114257Q9Y5W5Espacenet

1 to 10 of 275

See all 275 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,407

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleWIF1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant132025
P30CA016672Cancer Center Support Grant102025
P30CA006973Regional Oncology Research Center92025
P30CA015704Cancer Center Support Grant62025
P30CA076292Moffitt Cancer Center Support Grant62025
R01EY021797Development of Stem Cell-based Therapies for Limbal Stem Cell Deficiency52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA023108Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA062203Cancer Center Support Grant42025

1 to 10 of 1,407Source NIH's project files

See all 1,407 nih grants

Papers2,757

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia.J Pathol202642717886PubTator, text miningPubMed
Single-Cell Transcriptomic Profiling Reveals Superficial Zone Chondrocytes as a Catabolic and Senescent Focus in Osteoarthritis Cartilage.Cartilage202642647181PubTator, text miningPubMed
Lipid moieties of sonic hedgehog contribute to but are not essential for interaction with its inhibitor, WIF1.Biochem J202642606519PubTator, text miningPubMed
Chondroid Soft Tissue Tumors With FOS::PABPN1 Fusion: A New Entity? About Two Cases.Genes Chromosomes Cancer202642565647PubTator, text miningPubMed
miR-181d-5p promotes valvular calcification and directly targets Wnt inhibitory factor 1 in calcific aortic valve disease.Mol Cell Biochem202642474971PubTator, text miningPubMed
Cell-type signatures of Alzheimer's disease shared across population groups.Nature202642457956PubTator, text miningPubMed
Correction: The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition.
Mol Cancer202642421026PubTator, text miningPubMed
Wnt Signaling-Related Biomarkers in Gestational Diabetes Mellitus: Diagnostic Performance and Integrated Statistical Modeling.Diagnostics (Basel)202642351439PubTator, text miningPubMed
Machine Learning-Based Classification of Gliomas and Tumor Grades with SHAP-Guided Feature Interpretation.Genes (Basel)202642194968PubTator, text miningPubMed
Wnt-dependent ontogeny of acellular cementum-forming cementoblasts on the tooth root surface.Nat Commun202642129164PubTator, text miningPubMed

1 to 10 of 2,757

See all 2,757 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11197

GET https://conductscience.org/api/genes/v1/11197/patents?page=2