Gene · 11197
WIF1: Wnt inhibitory factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. WIF1: Wnt inhibitory factor 1. Genes, record 11197. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11197
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9Y5W5 | Wnt inhibitory factor 1 | 379 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents275
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 3294 | Q9Y5W5 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2869 | Q9Y5W5 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 14257 | Q9Y5W5 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 8074 | Q9Y5W5 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 8074 | Q9Y5W5 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2869 | Q9Y5W5 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3294 | Q9Y5W5 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 38177 | Q9Y5W5 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 14257 | Q9Y5W5 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 14257 | Q9Y5W5 | Espacenet |
1 to 10 of 275
See all 275 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,407
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | WIF1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 9 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 6 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 6 | 2025 |
| R01EY021797 | Development of Stem Cell-based Therapies for Limbal Stem Cell Deficiency | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 4 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 4 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,407Source NIH's project files
See all 1,407 nih grantsPapers2,757
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A transition zone enriched WIF1+ basal cell subtype is associated with benign prostatic hyperplasia. | J Pathol | 2026 | 42717886 | PubTator, text mining | PubMed |
| Single-Cell Transcriptomic Profiling Reveals Superficial Zone Chondrocytes as a Catabolic and Senescent Focus in Osteoarthritis Cartilage. | Cartilage | 2026 | 42647181 | PubTator, text mining | PubMed |
| Lipid moieties of sonic hedgehog contribute to but are not essential for interaction with its inhibitor, WIF1. | Biochem J | 2026 | 42606519 | PubTator, text mining | PubMed |
| Chondroid Soft Tissue Tumors With FOS::PABPN1 Fusion: A New Entity? About Two Cases. | Genes Chromosomes Cancer | 2026 | 42565647 | PubTator, text mining | PubMed |
| miR-181d-5p promotes valvular calcification and directly targets Wnt inhibitory factor 1 in calcific aortic valve disease. | Mol Cell Biochem | 2026 | 42474971 | PubTator, text mining | PubMed |
| Cell-type signatures of Alzheimer's disease shared across population groups. | Nature | 2026 | 42457956 | PubTator, text mining | PubMed |
Correction: The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition. | Mol Cancer | 2026 | 42421026 | PubTator, text mining | PubMed |
| Wnt Signaling-Related Biomarkers in Gestational Diabetes Mellitus: Diagnostic Performance and Integrated Statistical Modeling. | Diagnostics (Basel) | 2026 | 42351439 | PubTator, text mining | PubMed |
| Machine Learning-Based Classification of Gliomas and Tumor Grades with SHAP-Guided Feature Interpretation. | Genes (Basel) | 2026 | 42194968 | PubTator, text mining | PubMed |
| Wnt-dependent ontogeny of acellular cementum-forming cementoblasts on the tooth root surface. | Nat Commun | 2026 | 42129164 | PubTator, text mining | PubMed |
1 to 10 of 2,757
See all 2,757 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/11197
GET https://conductscience.org/api/genes/v1/11197/patents?page=2