ConductScience.org, home

Gene · 11213

IRAK3: interleukin 1 receptor associated kinase 3

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. IRAK3: interleukin 1 receptor associated kinase 3. Genes, record 11213. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11213

On this page

Gene

Symbol
IRAK3
HGNC
Name
interleukin 1 receptor associated kinase 3
HGNC
NCBI Gene ID
11213
NCBI Gene
HGNC ID
HGNC:17020
HGNC
Ensembl
ENSG00000090376
NCBI Gene
Aliases
ASRT5, IRAK-M, IRAKM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y616Interleukin-1 receptor-associated kinase 35963Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1450287Q9Y616Espacenet
EP 4650780 A22025-11-191859Q9Y616Espacenet
EP 4641201 A22025-10-291444Q9Y616Espacenet
JP 2025147176 A2025-10-067222Q9Y616Espacenet
JP 2025529142 A2025-09-046768Q9Y616Espacenet
US 12371689 B22025-07-296768Q9Y616Espacenet
JP 2025517969 A2025-06-121444Q9Y616Espacenet
JP 2025517970 A2025-06-121859Q9Y616Espacenet
JP 2025028160 A2025-02-287222Q9Y616Espacenet
KR 1020250010750 A2025-01-217222Q9Y616Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,211

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleIRAK3 papersNewest fiscal year
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)82025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital82025
R01HL076246Chemokines in healing myocardial infarction82025
R01HL085440Resolution of inflammation in healing myocardial infarcts82025
T32AI007413Research Training in Experimental Immunology52025
R01AA017986Heat shock protein 90 in alcoholic liver disease: targeting macrophage Function42025
R01DK099097Functional outcomes of inflammatory bowel disease associated variants42025
T32HL007749Multidisciplinary Training Program in Lung Disease42025
P30DK034989Yale Liver Center32025
P30DK056338Texas Medical Center Digestive Diseases Center32025

1 to 10 of 1,211Source NIH's project files

See all 1,211 nih grants

Papers1,496

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Novel RT‒qPCR-based blood signatures for the diagnosis of pulmonary tuberculosis.Sci Rep202642697888PubTator, text miningPubMed
Exploring the proteomic landscape of THP-1 monocytes through two-challenge LPS induction.Biochim Biophys Acta Proteins Proteom202642612956PubTator, text miningPubMed
Identification and verification of immunogenic cell death-related signatures derived from bone metastasis of prostate cancer based on multi-omics and machine learning algorithms.Comput Biol Chem202642419189PubTator, text miningPubMed
Lipoteichoic Acid Fraction from Lactiplantibacillus plantarum K8 Attenuates Inflammatory Responses and Promotes Antimicrobial Defense in Oral Epithelial Cells.Microorganisms202642354880PubTator, text miningPubMed
Exploring the gut-lung axis in post-liver transplant acute lung injury: A multi-omics approach.Acta Microbiol Immunol Hung202642258310PubTator, text miningPubMed
Activation of GABABR alleviates DSS-induced colitis in mice by rebalancing inflammatory responses and antioxidant capacity through IRAK-M.Int Immunopharmacol202642085846PubTator, text miningPubMed
Identification of immune-related genes shared between acute myocardial infarction and metabolic syndrome and construction of a diagnostic signature for acute myocardial infarction.Sci Prog202642049254PubTator, text miningPubMed
Interleukin-1 Receptor-Associated Kinase 3 Attenuates Chondrocyte Senescence and Osteoarthritis via Inhibition of the TLR7/9-NF-κB Axis.J Mol Histol202642029757PubTator, text miningPubMed
Dysregulation of myddosome complex genes its related to alendronate treatment failure in osteoporosis postmenopausal patients.Genet Mol Biol202641996696PubTator, text miningPubMed
Revealing causal associations of 91 inflammatory protein factors with endocarditis: Insights from genome-wide association study.Medicine (Baltimore)202641894309PubTator, text miningPubMed

1 to 10 of 1,496

See all 1,496 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11213

GET https://conductscience.org/api/genes/v1/11213/patents?page=2