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Gene · 1130

LYST: lysosomal trafficking regulator

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LYST: lysosomal trafficking regulator. Genes, record 1130. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1130

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Gene

Symbol
LYST
HGNC
Name
lysosomal trafficking regulator
HGNC
NCBI Gene ID
1130
NCBI Gene
HGNC ID
HGNC:1968
HGNC
Ensembl
ENSG00000143669
NCBI Gene
Aliases
CHS, CHS1, Mauve
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99698Lysosomal-trafficking regulator3,8010Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452153Q99698Espacenet
JP 2026004568 A2026-01-1452154Q99698Espacenet
EP 4641201 A22025-10-2911125Q99698Espacenet
EP 4641202 A22025-10-295809Q99698Espacenet
JP 2025517969 A2025-06-1211125Q99698Espacenet
KR 1020250017231 A2025-02-045809Q99698Espacenet
US 11884978 B22024-01-30585Q99698Espacenet
JP 2022141755 A2022-09-29259Q99698Espacenet
US 11446398 B22022-09-2047915Q99698Espacenet
JP 2022538497 A2022-09-02140Q99698Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,794

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLYST papersNewest fiscal year
ZIAHG000215Human Biochemical Genetics172025
P30DK063491Diabetes Research Center (DRC)162025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal92025
R01NS017950Precursors of Stroke Incidence and Prognosis72025
ZIAAG007380CLINICAL PROJECT: Age, Gene/Environment Susceptibility Study on the Multi-omics of Aging: A clinical epidemiologic prospective study62025
P30ES007048Environmental Exposures, Host Factors and Human Disease52025
ZIAES049019Genetic And Environmental Factors In Childhood Respiratory and Allergic Illness52025
R01MH112205Molecular Details of Psychoactive Drug Actions42025
R35GM127086Structural Biology Of G Protein-Coupled Receptors42025
ZIAAI000646Transgenic Animal Models Of Human Immune Defects42025

1 to 10 of 1,794Source NIH's project files

See all 1,794 nih grants

Papers2,270

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Haplotype-resolved autotetraploid genome of Dioscorea nipponica provides insights into recent polyploidization, metabolic rewiring, and environmental adaptation.Plant J202642804372PubTator, text miningPubMed
Integrated Transcriptomic and Biochemical Profiling Reveals the Regulatory Mechanism of Light Intensity-Induced Anthocyanin Biosynthesis in a Purple-Leaf Tea Cultivar.Plants (Basel)202642796836PubTator, text miningPubMed
Integrated Transcriptomics and Metabolomics to Reveal the Regulatory Mechanisms of Flavonoid Biosynthesis in Persicaria capitata Under Different Nitrogen Fertilization Levels.Metabolites202642783741PubTator, text miningPubMed
Regulatory mechanisms and multidimensional applications of blueberry anthocyanins: a review of current gaps and future directions.Eng Life Sci202642781482PubTator, text miningPubMed
Precision UV-B irradiation for flavonoid biofortification in indoor-cultivated Morus nigra: Integrated multi-omics and molecular docking insights.Food Chem202642748694PubTator, text miningPubMed
Metabolomics-transcriptomics analysis reveals the mechanism by which Gentiana lawrencei var. farreri promotes flowering under different diurnal temperatures.Front Plant Sci202642729383PubTator, text miningPubMed
Exploring the genetic spectrum of parkinsonism in Brazil.Parkinsonism Relat Disord202642691865PubTator, text miningPubMed
Spectrum of Primary Hemophagocytic Lymphohistiocytosis-Associated Gene Mutations in Chinese Patients.MedComm (2020)202642688879PubTator, text miningPubMed
Complexities in the Diagnostic Evaluation and Treatment of Infant Hemophagocytic Lymphohistiocytosis.Hematol Rep202642645790PubTator, text miningPubMed
A comparative study on the grouping of CHS-DRG 2.0 and 1.1 versions based on empirical analysis.Front Public Health202642643298PubTator, text miningPubMed

1 to 10 of 2,270

See all 2,270 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1130

GET https://conductscience.org/api/genes/v1/1130/patents?page=2