Gene · 1130
LYST: lysosomal trafficking regulator
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LYST: lysosomal trafficking regulator. Genes, record 1130. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1130
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99698 | Lysosomal-trafficking regulator | 3,801 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52153 | Q99698 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52154 | Q99698 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11125 | Q99698 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5809 | Q99698 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11125 | Q99698 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5809 | Q99698 | Espacenet |
| US 11884978 B2 | 2024-01-30 | 585 | Q99698 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 259 | Q99698 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47915 | Q99698 | Espacenet |
| JP 2022538497 A | 2022-09-02 | 140 | Q99698 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,794
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LYST papers | Newest fiscal year |
|---|---|---|---|
| ZIAHG000215 | Human Biochemical Genetics | 17 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 16 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 9 | 2025 |
| R01NS017950 | Precursors of Stroke Incidence and Prognosis | 7 | 2025 |
| ZIAAG007380 | CLINICAL PROJECT: Age, Gene/Environment Susceptibility Study on the Multi-omics of Aging: A clinical epidemiologic prospective study | 6 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 5 | 2025 |
| ZIAES049019 | Genetic And Environmental Factors In Childhood Respiratory and Allergic Illness | 5 | 2025 |
| R01MH112205 | Molecular Details of Psychoactive Drug Actions | 4 | 2025 |
| R35GM127086 | Structural Biology Of G Protein-Coupled Receptors | 4 | 2025 |
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 4 | 2025 |
1 to 10 of 1,794Source NIH's project files
See all 1,794 nih grantsPapers2,270
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Haplotype-resolved autotetraploid genome of Dioscorea nipponica provides insights into recent polyploidization, metabolic rewiring, and environmental adaptation. | Plant J | 2026 | 42804372 | PubTator, text mining | PubMed |
| Integrated Transcriptomic and Biochemical Profiling Reveals the Regulatory Mechanism of Light Intensity-Induced Anthocyanin Biosynthesis in a Purple-Leaf Tea Cultivar. | Plants (Basel) | 2026 | 42796836 | PubTator, text mining | PubMed |
| Integrated Transcriptomics and Metabolomics to Reveal the Regulatory Mechanisms of Flavonoid Biosynthesis in Persicaria capitata Under Different Nitrogen Fertilization Levels. | Metabolites | 2026 | 42783741 | PubTator, text mining | PubMed |
| Regulatory mechanisms and multidimensional applications of blueberry anthocyanins: a review of current gaps and future directions. | Eng Life Sci | 2026 | 42781482 | PubTator, text mining | PubMed |
| Precision UV-B irradiation for flavonoid biofortification in indoor-cultivated Morus nigra: Integrated multi-omics and molecular docking insights. | Food Chem | 2026 | 42748694 | PubTator, text mining | PubMed |
| Metabolomics-transcriptomics analysis reveals the mechanism by which Gentiana lawrencei var. farreri promotes flowering under different diurnal temperatures. | Front Plant Sci | 2026 | 42729383 | PubTator, text mining | PubMed |
| Exploring the genetic spectrum of parkinsonism in Brazil. | Parkinsonism Relat Disord | 2026 | 42691865 | PubTator, text mining | PubMed |
| Spectrum of Primary Hemophagocytic Lymphohistiocytosis-Associated Gene Mutations in Chinese Patients. | MedComm (2020) | 2026 | 42688879 | PubTator, text mining | PubMed |
| Complexities in the Diagnostic Evaluation and Treatment of Infant Hemophagocytic Lymphohistiocytosis. | Hematol Rep | 2026 | 42645790 | PubTator, text mining | PubMed |
| A comparative study on the grouping of CHS-DRG 2.0 and 1.1 versions based on empirical analysis. | Front Public Health | 2026 | 42643298 | PubTator, text mining | PubMed |
1 to 10 of 2,270
See all 2,270 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1130
GET https://conductscience.org/api/genes/v1/1130/patents?page=2