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Gene · 11309

SLCO2B1: solute carrier organic anion transporter family member 2B1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLCO2B1: solute carrier organic anion transporter family member 2B1. Genes, record 11309. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11309

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Gene

Symbol
SLCO2B1
HGNC
Name
solute carrier organic anion transporter family member 2B1
HGNC
NCBI Gene ID
11309
NCBI Gene
HGNC ID
HGNC:10962
HGNC
Ensembl
ENSG00000137491
NCBI Gene
Aliases
OATP-B, OATP2B1, OATPB, SLC21A9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O94956Solute carrier organic anion transporter family member 2B17090Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-292975O94956Espacenet
JP 2025517969 A2025-06-122975O94956Espacenet
JP 2025032204 A2025-03-1136120O94956Espacenet
EP 4461818 A22024-11-1336120O94956Espacenet
JP 2023058610 A2023-04-2536120O94956Espacenet
US 11446398 B22022-09-2082299O94956Espacenet
US 11400116 B22022-08-023662O94956Espacenet
JP 2022524081 A2022-04-27185270O94956Espacenet
JP 2020508652 A2020-03-2636120O94956Espacenet
KR 1020160117973 A2016-10-112O94956Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants696

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLCO2B1 papersNewest fiscal year
P30ES006694Southwest Environmental Health Sciences Center112025
R35GM122576Mechanisms of Altered Hepatic Transport: Impact on Drug Therapy112025
P50CA097186The Pacific Northwest Prostate Cancer SPORE82025
T32ES007091Training in Environmental Toxicology of Human Disease82025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer72025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)72025
T32ES007148Training in Environmental Toxicology62025
R01HD081299Ontogeny of drug transport52025
P30CA008748Cancer Center Support Grant42025
P30CA016056Roswell Park Cancer Center Support Grant42025

1 to 10 of 696Source NIH's project files

See all 696 nih grants

Papers1,629

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Lysosomal membrane localization of organic anion transporting polypeptide 2B1 in human hepatocytes.Drug Metab Dispos202642766917PubTator, text miningPubMed
Prenatal caffeine exposure disrupts the fetal-placental-maternal bile acid circulation and its associated placental transport mechanisms.Food Chem Toxicol202642342146PubTator, text miningPubMed
Modulation of remimazolam placental transfer via OATP2B1 by rosuvastatin in an in vitro 3D placental barrier model.Eur J Pharm Sci202642173384PubTator, text miningPubMed
Assessing the Potential Clinical Drug-Drug Interactions Between D-1553 (Garsorasib) and CYP450 Enzymes/Transporters via a Cocktail Approach.Clin Ther202642140797PubTator, text miningPubMed
Iron: Regulation, redox homeostasis, and ferroptosis in cancer.Ferroptosis Oxid Stress202642099806PubTator, text miningPubMed
Structural and functional analysis of OATP and ABCB1-mediated transport of pentamidine analogs: An integrated in vitro and in silico approach.Eur J Pharm Sci202642009232PubTator, text miningPubMed
The striking divergence of ABCB1 mRNA expression and P-glycoprotein protein levels in M1 and M2 macrophages associates with the microRNA miR-21-3p, a regulator of "RNA binding protein, mRNA processing factor".
Naunyn Schmiedebergs Arch Pharmacol202641964673PubTator, text miningPubMed
Plasma coproporphyrins for evaluating OATP1B and OATP2B1 activities: Coproporphyrin-III unsuitable as an OATP2B1 biomarker in Japanese general population.Drug Metab Dispos202641946330PubTator, text miningPubMed
Maternal transfer of bisphenol analogues and their conjugated metabolites.J Hazard Mater202641934853PubTator, text miningPubMed
An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis.Cancer Res202641886603PubTator, text miningPubMed

1 to 10 of 1,629

See all 1,629 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11309

GET https://conductscience.org/api/genes/v1/11309/patents?page=2