ConductScience.org, home

Gene · 11331

PHB2: prohibitin 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PHB2: prohibitin 2. Genes, record 11331. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11331

On this page

Gene

Symbol
PHB2
HGNC
Name
prohibitin 2
HGNC
NCBI Gene ID
11331
NCBI Gene
HGNC ID
HGNC:30306
HGNC
Ensembl
ENSG00000215021
NCBI Gene
Aliases
BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99623Prohibitin-22998Ensembl, GeneID, HGNC

Source UniProt

Patents72

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12605438 B22026-04-2110Q99623Espacenet
JP 2026004568 A2026-01-1459153Q99623Espacenet
EP 4650780 A22025-11-1916194Q99623Espacenet
EP 4641202 A22025-10-297984Q99623Espacenet
JP 2025147176 A2025-10-0615483Q99623Espacenet
WO 2025183089 A2025-09-041Q99623Espacenet
JP 2025517970 A2025-06-1216194Q99623Espacenet
JP 2025028160 A2025-02-2815483Q99623Espacenet
KR 1020250017231 A2025-02-047984Q99623Espacenet
KR 1020250010750 A2025-01-2115483Q99623Espacenet

1 to 10 of 72

See all 72 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,673

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePHB2 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant52025
R01HD007857Sex Hormone Receptor Component And The Cell Genome52025
P30CA010815Consolidated Basic Cancer Research Program42025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA047904Cancer Center Support Grant42025
P42ES016465Center for the Science, Technology, and Emerging Health Risks of PAHs42025
R01HD094937Modeling Normal and Abnormal Trophoblasts42025
T32ES007060Integrated Regional Training Program in Environmental Health Sciences (IRTP)42025
P30CA006927Comprehensive Cancer Center Program at Fox Chase32025

1 to 10 of 1,673Source NIH's project files

See all 1,673 nih grants

Papers2,922

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Controlled microfluidic tank integrated AgNPs-coated paper-based impedimetric immunosensor for leukemia biomarker detection and complete validation through 3i-study in-silico, in-vitro, in-vivo.Biosens Bioelectron202742715745PubTator, text miningPubMed
Bioactive Peptides in Functional Foods: From Production and Validation to Commercialization, Regulatory Hurdles, and Future Prospects.J Food Sci202642817796PubTator, text miningPubMed
[The mitochondrial protein encoded by circUSP25 promotes colon cancer cell proliferation and migration].Nan Fang Yi Ke Da Xue Xue Bao202642812058PubTator, text miningPubMed
Prohibitin 2 mediates the mitochondrial protective effect of the whey-derived tetrapeptide Gly-Thr-Trp-Tyr.Biochem Biophys Res Commun202642785177PubTator, text miningPubMed
Proteomics of heterogeneous megakaryocytes identifies JI051 as an enhancer of platelet biogenesis.Life Sci Alliance202642778423PubTator, text miningPubMed
PITX1 facilitates the proliferation and tumorigenesis of NSCLC cells via potentiating PHB2-mediated AKT activity.Cell Signal202642731741PubTator, text miningPubMed
PHB2 Promotes Glycolytic Reprogramming in Triple-Negative Breast Cancer Through FOXM1-Dependent Activation of LDHB.Carcinogenesis202642710061PubTator, text miningPubMed
Characterization of mitochondria in trophoblast cells derived from control and early-onset preeclamptic pregnancies via induced pluripotent stem cells.Biol Reprod202642667657PubTator, text miningPubMed
Targeting the PHB2-ACSL3 Lipid-Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer.Adv Sci (Weinh)202642627686PubTator, text miningPubMed
Oxidative Damage Induced Disruption of Mitochondrial Quality Control Underlying Abnormal Energy Metabolism in Peripheral Leukocytes of Schizophrenia Patients.Schizophr Bull Open202642583432PubTator, text miningPubMed

1 to 10 of 2,922

See all 2,922 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11331

GET https://conductscience.org/api/genes/v1/11331/patents?page=2