Gene · 11331
PHB2: prohibitin 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PHB2: prohibitin 2. Genes, record 11331. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11331
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99623 | Prohibitin-2 | 299 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents72
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12605438 B2 | 2026-04-21 | 10 | Q99623 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 59153 | Q99623 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 16194 | Q99623 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 7984 | Q99623 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15483 | Q99623 | Espacenet |
| WO 2025183089 A | 2025-09-04 | 1 | Q99623 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 16194 | Q99623 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15483 | Q99623 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 7984 | Q99623 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15483 | Q99623 | Espacenet |
1 to 10 of 72
See all 72 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,673
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PHB2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01HD007857 | Sex Hormone Receptor Component And The Cell Genome | 5 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 4 | 2025 |
| P42ES016465 | Center for the Science, Technology, and Emerging Health Risks of PAHs | 4 | 2025 |
| R01HD094937 | Modeling Normal and Abnormal Trophoblasts | 4 | 2025 |
| T32ES007060 | Integrated Regional Training Program in Environmental Health Sciences (IRTP) | 4 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 3 | 2025 |
1 to 10 of 1,673Source NIH's project files
See all 1,673 nih grantsPapers2,922
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Controlled microfluidic tank integrated AgNPs-coated paper-based impedimetric immunosensor for leukemia biomarker detection and complete validation through 3i-study in-silico, in-vitro, in-vivo. | Biosens Bioelectron | 2027 | 42715745 | PubTator, text mining | PubMed |
| Bioactive Peptides in Functional Foods: From Production and Validation to Commercialization, Regulatory Hurdles, and Future Prospects. | J Food Sci | 2026 | 42817796 | PubTator, text mining | PubMed |
| [The mitochondrial protein encoded by circUSP25 promotes colon cancer cell proliferation and migration]. | Nan Fang Yi Ke Da Xue Xue Bao | 2026 | 42812058 | PubTator, text mining | PubMed |
| Prohibitin 2 mediates the mitochondrial protective effect of the whey-derived tetrapeptide Gly-Thr-Trp-Tyr. | Biochem Biophys Res Commun | 2026 | 42785177 | PubTator, text mining | PubMed |
| Proteomics of heterogeneous megakaryocytes identifies JI051 as an enhancer of platelet biogenesis. | Life Sci Alliance | 2026 | 42778423 | PubTator, text mining | PubMed |
| PITX1 facilitates the proliferation and tumorigenesis of NSCLC cells via potentiating PHB2-mediated AKT activity. | Cell Signal | 2026 | 42731741 | PubTator, text mining | PubMed |
| PHB2 Promotes Glycolytic Reprogramming in Triple-Negative Breast Cancer Through FOXM1-Dependent Activation of LDHB. | Carcinogenesis | 2026 | 42710061 | PubTator, text mining | PubMed |
| Characterization of mitochondria in trophoblast cells derived from control and early-onset preeclamptic pregnancies via induced pluripotent stem cells. | Biol Reprod | 2026 | 42667657 | PubTator, text mining | PubMed |
| Targeting the PHB2-ACSL3 Lipid-Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer. | Adv Sci (Weinh) | 2026 | 42627686 | PubTator, text mining | PubMed |
| Oxidative Damage Induced Disruption of Mitochondrial Quality Control Underlying Abnormal Energy Metabolism in Peripheral Leukocytes of Schizophrenia Patients. | Schizophr Bull Open | 2026 | 42583432 | PubTator, text mining | PubMed |
1 to 10 of 2,922
See all 2,922 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/11331
GET https://conductscience.org/api/genes/v1/11331/patents?page=2