Gene · 11338
U2AF2: U2 small nuclear RNA auxiliary factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. U2AF2: U2 small nuclear RNA auxiliary factor 2. Genes, record 11338. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11338
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P26368 | Splicing factor U2AF 65 kDa subunit | 475 | 40 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 4524 | P26368 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4524 | P26368 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 94374 | P26368 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 197345 | P26368 | Espacenet |
| JP 2019033757 A | 2019-03-07 | 24867 | P26368 | Espacenet |
| JP 2017123847 A | 2017-07-20 | 24867 | P26368 | Espacenet |
| US 9504734 B2 | 2016-11-29 | 6251 | P26368 | Espacenet |
| WO 2016103269 A1 | 2016-06-30 | 4360 | P26368 | Espacenet |
| US 9283287 B2 | 2016-03-15 | 6251 | P26368 | Espacenet |
| JP 2015519881 A | 2015-07-16 | 24867 | P26368 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,291
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | U2AF2 papers | Newest fiscal year |
|---|---|---|---|
| R01GM070503 | Molecular Recognition During Pre-mRNA Splicing | 31 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 23 | 2025 |
| R01HL128239 | Genetic and molecular basis for SRSF2 mutations in myelodysplasia | 11 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R35GM118136 | Regulation of mRNA processing: Mechanisms and Consequences | 8 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 7 | 2025 |
| R01CA174777 | AR Gene Rearrangements and AR Signaling in Prostate Cancer | 6 | 2025 |
| ZIASC010357 | Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses | 6 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 5 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 5 | 2025 |
1 to 10 of 1,291Source NIH's project files
See all 1,291 nih grantsPapers2,147
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Correction to "De Novo 2.2 Mb 19q13.42-q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model". | Am J Med Genet A | 2026 | 42808645 | PubTator, text mining | PubMed |
| CircRAD23B-208aa Promotes Gastric Cancer Progression by Activating the Unfolded Protein Response through PDIA5 SUMOylation. | Research (Wash D C) | 2026 | 42491210 | PubTator, text mining | PubMed |
| Exploitation of host U2AF1 and U2AF2 splicing factors facilitates mosquito-borne orthoflavivirus infection across species. | Nucleic Acids Res | 2026 | 42464737 | PubTator, text mining | PubMed |
| Functional implications of SNPs in spliceosomal network: a structural systems biology approach. | J Biomol Struct Dyn | 2026 | 42343645 | PubTator, text mining | PubMed |
| Divergent RNA structures support accurate splicing of the SF3B1-sensitive MAP3K7 intron. | bioRxiv | 2026 | 42239186 | PubTator, text mining | PubMed |
| KAS-CUT&Tag for direct mapping of transcription bubbles. | bioRxiv | 2026 | 42239153 | PubTator, text mining | PubMed |
| U2AF2-regulated alternative splicing of UPP1 promotes NSCLC progression by enhancing glycolysis. | Cell Commun Signal | 2026 | 42151969 | PubTator, text mining | PubMed |
| The competition between splicing and 3' processing shapes the human transcriptome. | Genes Dev | 2026 | 42140670 | PubTator, text mining | PubMed |
| De Novo 2.2 Mb 19q13.42-q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model. | Am J Med Genet A | 2026 | 42135263 | PubTator, text mining | PubMed |
| Machine learning-driven identification of circulating biomarkers and therapeutic compounds for diabetic retinopathy. | Hum Genomics | 2026 | 42129911 | PubTator, text mining | PubMed |
1 to 10 of 2,147
See all 2,147 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/11338
GET https://conductscience.org/api/genes/v1/11338/patents?page=2