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Gene · 11338

U2AF2: U2 small nuclear RNA auxiliary factor 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. U2AF2: U2 small nuclear RNA auxiliary factor 2. Genes, record 11338. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11338

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Gene

Symbol
U2AF2
HGNC
Name
U2 small nuclear RNA auxiliary factor 2
HGNC
NCBI Gene ID
11338
NCBI Gene
HGNC ID
HGNC:23156
HGNC
Ensembl
ENSG00000063244
NCBI Gene
Aliases
DEVDFB, U2AF65
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P26368Splicing factor U2AF 65 kDa subunit47540Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-194524P26368Espacenet
JP 2025517970 A2025-06-124524P26368Espacenet
US 11446398 B22022-09-2094374P26368Espacenet
JP 2022524081 A2022-04-27197345P26368Espacenet
JP 2019033757 A2019-03-0724867P26368Espacenet
JP 2017123847 A2017-07-2024867P26368Espacenet
US 9504734 B22016-11-296251P26368Espacenet
WO 2016103269 A12016-06-304360P26368Espacenet
US 9283287 B22016-03-156251P26368Espacenet
JP 2015519881 A2015-07-1624867P26368Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,291

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleU2AF2 papersNewest fiscal year
R01GM070503Molecular Recognition During Pre-mRNA Splicing312025
P30CA008748Cancer Center Support Grant232025
R01HL128239Genetic and molecular basis for SRSF2 mutations in myelodysplasia112025
P30CA016672Cancer Center Support Grant92025
R35GM118136Regulation of mRNA processing: Mechanisms and Consequences82025
P30CA016058Cancer Center Support Grant72025
R01CA174777AR Gene Rearrangements and AR Signaling in Prostate Cancer62025
ZIASC010357Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses62025
P01CA013106Targeting Transcription and Splicing in Cancer52025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer52025

1 to 10 of 1,291Source NIH's project files

See all 1,291 nih grants

Papers2,147

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction to "De Novo 2.2 Mb 19q13.42-q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model".Am J Med Genet A202642808645PubTator, text miningPubMed
CircRAD23B-208aa Promotes Gastric Cancer Progression by Activating the Unfolded Protein Response through PDIA5 SUMOylation.Research (Wash D C)202642491210PubTator, text miningPubMed
Exploitation of host U2AF1 and U2AF2 splicing factors facilitates mosquito-borne orthoflavivirus infection across species.Nucleic Acids Res202642464737PubTator, text miningPubMed
Functional implications of SNPs in spliceosomal network: a structural systems biology approach.J Biomol Struct Dyn202642343645PubTator, text miningPubMed
Divergent RNA structures support accurate splicing of the SF3B1-sensitive MAP3K7 intron.bioRxiv202642239186PubTator, text miningPubMed
KAS-CUT&Tag for direct mapping of transcription bubbles.bioRxiv202642239153PubTator, text miningPubMed
U2AF2-regulated alternative splicing of UPP1 promotes NSCLC progression by enhancing glycolysis.Cell Commun Signal202642151969PubTator, text miningPubMed
The competition between splicing and 3' processing shapes the human transcriptome.Genes Dev202642140670PubTator, text miningPubMed
De Novo 2.2 Mb 19q13.42-q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model.Am J Med Genet A202642135263PubTator, text miningPubMed
Machine learning-driven identification of circulating biomarkers and therapeutic compounds for diabetic retinopathy.Hum Genomics202642129911PubTator, text miningPubMed

1 to 10 of 2,147

See all 2,147 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11338

GET https://conductscience.org/api/genes/v1/11338/patents?page=2