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MGLL: monoglyceride lipase
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Gene · 11343

Papers2,780

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,780

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TitleJournalYearPMIDFound bySource
E2F1 down-regulation promotes lipid droplet accumulation and endometriosis development through impaired MGLL-mediated lipid mobilization.Clin Sci (Lond)202642803692PubTator, text miningPubMed
Monoacylglycerol Lipase Inhibition by JZL184 Improves Neurological Outcomes and Survival after Cardiac Arrest via 2-AG-Mediated Restoration of Cerebral Microcirculation.Cannabis Cannabinoid Res202642798153PubTator, text miningPubMed
Tai Chi exercise of short duration alters circulating oxylipins in postmenopausal women: a pilot study.Front Med (Lausanne)202642740961PubTator, text miningPubMed
Lipase ITB 2.1: a structure- and function-validated model for anti-obesity drug screening.Mol Divers202642732036PubTator, text miningPubMed
Computational discovery and dynamic profiling of dual acetylcholinesterase and monoacylglycerol lipase inhibitors for Alzheimer's disease.Mol Divers202642693315PubTator, text miningPubMed
From Glycocode to Precision Oncology: Therapeutic Strategies Targeting Aberrant O-GalNAc Glycosylation in Cancer.Chem Rev202642677388PubTator, text miningPubMed
Chronic THC exposure modulates behavioral outcomes and endocannabinoid signaling in HIV-1 Tg26 mice in a sex-dependent manner.Brain Res Bull202642660238PubTator, text miningPubMed
Exploring sex differences in endocannabinoid system biomarkers and their relationship with antidepressant treatment outcomes in major depressive disorder: a CAN-BIND 1 secondary analysis.Eur Arch Psychiatry Clin Neurosci202642640306PubTator, text miningPubMed
Iso- and Benzisothiazolinone Inhibitors of Monoacylglycerol Lipase: Exploring On-Target Activity Through Scaffold Decoration and In Situ Warhead Generation.ChemMedChem202642638513PubTator, text miningPubMed
Advances in Small Molecule Research Targeting Monoacylglycerol Lipase in Drug Discovery.Med Res Rev202642478312PubTator, text miningPubMed
Recent Progress in the Development of Selective MAGL Modulators (2020-2026).Molecules202642451720PubTator, text miningPubMed
Alteration of epidermal lipid metabolism by 2-linoleoylglycerol in a 3D skin model.Sci Rep202642431977PubTator, text miningPubMed
The CB1 receptor as a convergence hub linking stress, sleep and appetite regulation: An integrative neurobiological model.Neurosci Biobehav Rev202642431566PubTator, text miningPubMed
Lipid peroxidation impacts orthoflavivirus infection in a virus-dependent manner.Cell Death Dis202642420242PubTator, text miningPubMed
The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development.Cell Death Dis202642401573PubTator, text miningPubMed
Heterocyclic Scaffolds as Therapeutic Agents in Multiple Sclerosis: Mechanisms and SAR Study.Cent Nerv Syst Agents Med Chem202642393898PubTator, text miningPubMed
The Role of Monoacylglycerol Lipase in Substance Use: A Systematic Review of Preclinical Studies.Biol Psychiatry202642342190PubTator, text miningPubMed
Therapeutic activation of the endocannabinoid system for opioid use disorder, chronic pain, and cancer-related pain: a review of current evidence.Expert Opin Ther Targets202642295097PubTator, text miningPubMed
Recent advances in neurodegenerative diseases therapeutics: The inhibition of monoacylglycerol lipase strategy.Neuroscience202642285406PubTator, text miningPubMed
Multi-scale computational analysis of monoacylglycerol lipase inhibition as a new therapeutic strategy for hepatocellular carcinoma.Sci Rep202642243214PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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