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Gene · 11345

GABARAPL2: GABA type A receptor associated protein like 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GABARAPL2: GABA type A receptor associated protein like 2. Genes, record 11345. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/11345

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Gene

Symbol
GABARAPL2
HGNC
Name
GABA type A receptor associated protein like 2
HGNC
NCBI Gene ID
11345
NCBI Gene
HGNC ID
HGNC:13291
HGNC
Ensembl
ENSG00000034713
NCBI Gene
Aliases
ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P60520Gamma-aminobutyric acid receptor-associated protein-like 21175Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447168P60520Espacenet
EP 4650780 A22025-11-1969P60520Espacenet
JP 2025517970 A2025-06-1269P60520Espacenet
US 11866516 B22024-01-0913P60520Espacenet
US 11860162 B22024-01-021464P60520Espacenet
US 11446398 B22022-09-2033737P60520Espacenet
JP 2022537339 A2022-08-25137P60520Espacenet
US 11396529 B22022-07-2613P60520Espacenet
JP 2022524081 A2022-04-27136708P60520Espacenet
WO 2021201116 A2021-10-0738P60520Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,238

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGABARAPL2 papersNewest fiscal year
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.162025
R37AI042999Pattern Recognition Receptors and Autophagy in Mtb Control in AIDS122025
R01CA126792Autophagy and Pro-metastatic Differentiation112025
R35GM131919The mechanism and regulation of autophagy82025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control62025
P30CA021765Cancer Center Support Grant (CCSG)52025
P40OD010440Caenorhabditis Genetics Center52025
R01AG038664Regulation of the Autophagy Pathway with Age and in Long-lived Animals52025
R01AG057462Endolysosomal defects in secretory autophagy and microglial toxicity in FTD52025
P30CA016520Abramson Cancer Center Support Grant42025

1 to 10 of 1,238Source NIH's project files

See all 1,238 nih grants

Papers2,168

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
SOX9 attenuates osteoarthritis by regulating autophagy via the PI3K/Akt/mTOR pathway.Int J Biol Macromol202642749001PubTator, text miningPubMed
Aquaporin 3 Promoter Polymorphisms Reduce Gene Expression and Associate Altered Autophagy-Related Gene Signatures With Atopic Dermatitis Susceptibility.Exp Dermatol202642744597PubTator, text miningPubMed
TBK1 puts the brakes on IRGQ-mediated autophagy.Autophagy202642576195PubTator, text miningPubMed
GABARAPL2 and Alix mediate reciprocal regulation of autophagy and exosome pathways to facilitate cellular homeostasis.Mol Biol Rep202642435234PubTator, text miningPubMed
A novel homozygous ARFGEF2 splice-site variant causing periventricular nodular heterotopia with microcephaly.Front Pediatr202642255913PubTator, text miningPubMed
Autophagy-centered gene networks reveal prognostic biomarkers and therapeutic targets in esophageal cancer.Discov Oncol202642204123PubTator, text miningPubMed
TBK1 restricts IRGQ-mediated autophagy.Nat Commun202642129229PubTator, text miningPubMed
GABARAPL1 is important for the activation of HRI during eIF2α phosphorylation-dependent stress response to sodium arsenite.Sci Rep202641904211PubTator, text miningPubMed
Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal Transduct Target Ther202641881983PubTator, text miningPubMed
Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides.Cancer Med202641811763PubTator, text miningPubMed

1 to 10 of 2,168

See all 2,168 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/11345

GET https://conductscience.org/api/genes/v1/11345/patents?page=2