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Gene · 114769

CARD16: caspase recruitment domain family member 16

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CARD16: caspase recruitment domain family member 16. Genes, record 114769. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/114769

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Gene

Symbol
CARD16
HGNC
Name
caspase recruitment domain family member 16
HGNC
NCBI Gene ID
114769
NCBI Gene
HGNC ID
HGNC:33701
HGNC
Ensembl
ENSG00000204397
NCBI Gene
Aliases
COP, COP1, LLID-114769, PSEUDO-ICE
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5EG05Caspase recruitment domain-containing protein 161970Ensembl, GeneID, HGNC

Source UniProt

Patents8

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025024198 A2025-02-199606Q5EG05Espacenet
US 11446398 B22022-09-2012338Q5EG05Espacenet
JP 2022524081 A2022-04-27115309Q5EG05Espacenet
US 11078247 B22021-08-031589Q5EG05Espacenet
US 9827332 B22017-11-289606Q5EG05Espacenet
JP 2017121243 A2017-07-1353574Q5EG05Espacenet
US 9254311 B22016-02-099606Q5EG05Espacenet
JP 2015513912 A2015-05-1853574Q5EG05Espacenet

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants610

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCARD16 papersNewest fiscal year
R37AI054165Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse Pathogens62025
UM1AI068635SDMC: HIV Vaccine Trials Network62025
P30CA016672Cancer Center Support Grant52025
P30CA008748Cancer Center Support Grant42025
UM1AI068614HIV Vaccines Clinical Trials Network Leadership and Operations Center42025
R01AI124491NLRP1 and CARD8 Inflammasomes: Assembly, Regulation and Stress Sensing32025
P30CA016086Cancer Center Support Grant22025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center22025
R01AI036082Neutralization of primary HIV-1 viruses22025
R35GM122567Near-infrared fluorescent probes and optogenetic tools22025

1 to 10 of 610Source NIH's project files

See all 610 nih grants

Papers1,841

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Gait and plantar pressure changes after medial open-wedge high tibial osteotomy combined with arthroscopic partial meniscectomy.Front Bioeng Biotechnol202642656967PubTator, text miningPubMed
Retraction notice to "Potential mechanism of CARD16 protein action and susceptibility to sepsis in the elderly infected population: Through transcriptome analysis of blood" [Int. J. Biol. Macromol. 281 (2024) 136578].
Int J Biol Macromol202642586828PubTator, text miningPubMed
Heterogeneity and plasticity of tumor-associated macrophages in oral squamous cell carcinoma: implications for diagnosis and tumor microenvironment characterization.Front Immunol202642495621PubTator, text miningPubMed
Postural control and knee joint importance during quiet standing in individuals with anterior cruciate ligament reconstruction.PLoS One202642475325PubTator, text miningPubMed
Annealing-Regulated Co3(PO4)2 for Enhanced Electrochemical Kinetics in Asymmetric Supercapacitors.Molecules202642357551PubTator, text miningPubMed
Crystal Structure and Morphology-Controlled Synthesis of Co1-xMnxP Nanocrystals and Their Composition-Dependent Electrocatalytic Activity for the Hydrogen Evolution Reaction.ACS Appl Mater Interfaces202642141989PubTator, text miningPubMed
Phase Boundary Engineering of Co2P-CoP Branched Nanoparticles Enhances Cobalt Oxidation for Oxygen Evolution Electrocatalysis.Adv Mater202642138571PubTator, text miningPubMed
Robust heterostructured CoP/FeP@IF enables highly effective electrocatalytic reduction of nitrate to ammonia.J Hazard Mater202641962367PubTator, text miningPubMed
Multifaceted Role of Copper Homeostasis in Gut Health: From Molecular Mechanisms to Therapeutic Interventions.Cells202641892335PubTator, text miningPubMed
Predictive simulations of postural control: exploring the role of signal noise and neural delays in Parkinson's disease.Sci Rep202641876699PubTator, text miningPubMed

1 to 10 of 1,841

See all 1,841 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/114769

GET https://conductscience.org/api/genes/v1/114769/grants?page=2