Gene · 114769
CARD16: caspase recruitment domain family member 16
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CARD16: caspase recruitment domain family member 16. Genes, record 114769. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/114769
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q5EG05 | Caspase recruitment domain-containing protein 16 | 197 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents8
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025024198 A | 2025-02-19 | 9606 | Q5EG05 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 12338 | Q5EG05 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 115309 | Q5EG05 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 1589 | Q5EG05 | Espacenet |
| US 9827332 B2 | 2017-11-28 | 9606 | Q5EG05 | Espacenet |
| JP 2017121243 A | 2017-07-13 | 53574 | Q5EG05 | Espacenet |
| US 9254311 B2 | 2016-02-09 | 9606 | Q5EG05 | Espacenet |
| JP 2015513912 A | 2015-05-18 | 53574 | Q5EG05 | Espacenet |
Drugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants610
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CARD16 papers | Newest fiscal year |
|---|---|---|---|
| R37AI054165 | Statistical Methods for Efficacy Trials of Vaccines and Monoclonal Antibodies Against Genetically-Diverse Pathogens | 6 | 2025 |
| UM1AI068635 | SDMC: HIV Vaccine Trials Network | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| UM1AI068614 | HIV Vaccines Clinical Trials Network Leadership and Operations Center | 4 | 2025 |
| R01AI124491 | NLRP1 and CARD8 Inflammasomes: Assembly, Regulation and Stress Sensing | 3 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 2 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 2 | 2025 |
| R01AI036082 | Neutralization of primary HIV-1 viruses | 2 | 2025 |
| R35GM122567 | Near-infrared fluorescent probes and optogenetic tools | 2 | 2025 |
1 to 10 of 610Source NIH's project files
See all 610 nih grantsPapers1,841
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Gait and plantar pressure changes after medial open-wedge high tibial osteotomy combined with arthroscopic partial meniscectomy. | Front Bioeng Biotechnol | 2026 | 42656967 | PubTator, text mining | PubMed |
Retraction notice to "Potential mechanism of CARD16 protein action and susceptibility to sepsis in the elderly infected population: Through transcriptome analysis of blood" [Int. J. Biol. Macromol. 281 (2024) 136578]. | Int J Biol Macromol | 2026 | 42586828 | PubTator, text mining | PubMed |
| Heterogeneity and plasticity of tumor-associated macrophages in oral squamous cell carcinoma: implications for diagnosis and tumor microenvironment characterization. | Front Immunol | 2026 | 42495621 | PubTator, text mining | PubMed |
| Postural control and knee joint importance during quiet standing in individuals with anterior cruciate ligament reconstruction. | PLoS One | 2026 | 42475325 | PubTator, text mining | PubMed |
| Annealing-Regulated Co3(PO4)2 for Enhanced Electrochemical Kinetics in Asymmetric Supercapacitors. | Molecules | 2026 | 42357551 | PubTator, text mining | PubMed |
| Crystal Structure and Morphology-Controlled Synthesis of Co1-xMnxP Nanocrystals and Their Composition-Dependent Electrocatalytic Activity for the Hydrogen Evolution Reaction. | ACS Appl Mater Interfaces | 2026 | 42141989 | PubTator, text mining | PubMed |
| Phase Boundary Engineering of Co2P-CoP Branched Nanoparticles Enhances Cobalt Oxidation for Oxygen Evolution Electrocatalysis. | Adv Mater | 2026 | 42138571 | PubTator, text mining | PubMed |
| Robust heterostructured CoP/FeP@IF enables highly effective electrocatalytic reduction of nitrate to ammonia. | J Hazard Mater | 2026 | 41962367 | PubTator, text mining | PubMed |
| Multifaceted Role of Copper Homeostasis in Gut Health: From Molecular Mechanisms to Therapeutic Interventions. | Cells | 2026 | 41892335 | PubTator, text mining | PubMed |
| Predictive simulations of postural control: exploring the role of signal noise and neural delays in Parkinson's disease. | Sci Rep | 2026 | 41876699 | PubTator, text mining | PubMed |
1 to 10 of 1,841
See all 1,841 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/114769
GET https://conductscience.org/api/genes/v1/114769/grants?page=2