Gene · 1152
CKB: creatine kinase B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CKB: creatine kinase B. Genes, record 1152. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1152
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P12277 | Creatine kinase B-type | 381 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents77
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 42334 | P12277 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3922 | P12277 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3922 | P12277 | Espacenet |
| JP 2025013795 A | 2025-01-28 | 26 | P12277 | Espacenet |
| JP 2024528705 A | 2024-07-30 | 1 | P12277 | Espacenet |
| EP 4373582 A1 | 2024-05-29 | 1 | P12277 | Espacenet |
| US 11965885 B2 | 2024-04-23 | 29 | P12277 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1479 | P12277 | Espacenet |
| JP 2023510658 A | 2023-03-15 | 4 | P12277 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 20147 | P12277 | Espacenet |
1 to 10 of 77
See all 77 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,266
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CKB papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 4 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 4 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
| P30CA118100 | University of New Mexico Cancer Center Support Grant | 3 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 3 | 2025 |
| P20GM103427 | Nebraska Research Network in Functional Genomics | 2 | 2025 |
1 to 10 of 1,266Source NIH's project files
See all 1,266 nih grantsPapers2,289
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation. | Adv Sci (Weinh) | 2026 | 42801620 | PubTator, text mining | PubMed |
| Candidate proteomic indirect-effect signals linking dementia to probable muscle-bone fragility: a UK Biobank cohort study. | Front Med (Lausanne) | 2026 | 42780496 | PubTator, text mining | PubMed |
| Integrative plasma proteomic network analysis identifies physical activity-associated protein modules potentially mediating type 2 diabetes risk. | Cardiovasc Diabetol | 2026 | 42778924 | PubTator, text mining | PubMed |
| An AI-Driven Chemogenomics Knowledgebase for Human-Transmissible Pathogens: A Platform for Antimicrobial Drug Discovery. | J Chem Inf Model | 2026 | 42743006 | PubTator, text mining | PubMed |
| A self-sustaining hypoxia inducible factor-1α-creatine kinase B feedforward circuit drives macrophage-mediated kidney fibrosis. | Kidney Int | 2026 | 42628836 | PubTator, text mining | PubMed |
| Derivation and validation of a pre-bronchodilator FEV1/FVC threshold for point-of-care diagnosis triage of COPD in primary care: a multi-cohort population-based study. | Lancet Reg Health West Pac | 2026 | 42621354 | PubTator, text mining | PubMed |
| Dimer opening enables brain-type creatine kinase to sense membrane curvature. | bioRxiv | 2026 | 42620321 | PubTator, text mining | PubMed |
| How Often are druggable mutations detectable in Metastatic Castration Resistant Prostate Cancer? | Urol Int | 2026 | 42594033 | PubTator, text mining | PubMed |
| Kinetic and inhibitory profiling of serum MMP-9 in acute spinal cord injury: neurochemical links to injury severity and neuroinflammation. | Acta Neurol Belg | 2026 | 42570066 | PubTator, text mining | PubMed |
| Complement System-Related Genes in Diabetic Nephropathy: Screening for Potential Targets of the Mechanism. | J Diabetes Res | 2026 | 42402786 | PubTator, text mining | PubMed |
1 to 10 of 2,289
See all 2,289 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1152
GET https://conductscience.org/api/genes/v1/1152/patents?page=2