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Gene · 116519

APOA5: apolipoprotein A5

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. APOA5: apolipoprotein A5. Genes, record 116519. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/116519

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Gene

Symbol
APOA5
HGNC
Name
apolipoprotein A5
HGNC
NCBI Gene ID
116519
NCBI Gene
HGNC ID
HGNC:17288
HGNC
Ensembl
ENSG00000110243
NCBI Gene
Aliases
APOA-V, APOAV, RAP3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6Q788Apolipoprotein A-V3660Ensembl, GeneID, HGNC

Source UniProt

Patents111

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437646Q6Q788Espacenet
JP 2026004568 A2026-01-1437648Q6Q788Espacenet
EP 4650780 A22025-11-19688Q6Q788Espacenet
EP 4640849 A22025-10-2983Q6Q788Espacenet
EP 4641201 A22025-10-29482Q6Q788Espacenet
JP 2025147176 A2025-10-06945Q6Q788Espacenet
JP 2025147176 A2025-10-06946Q6Q788Espacenet
JP 2025529142 A2025-09-045502Q6Q788Espacenet
US 12371689 B22025-07-295502Q6Q788Espacenet
JP 2025519096 A2025-06-2483Q6Q788Espacenet

1 to 10 of 111

See all 111 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,707

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleAPOA5 papersNewest fiscal year
P30DK063491Diabetes Research Center (DRC)212025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal92025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)72025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
R01HL109946Using genetics to discover mechanisms of abdominal aortic aneurysm62025
R01NS017950Precursors of Stroke Incidence and Prognosis62025
T32HL007208Integrated, Multidisciplinary Training in Cardiovascular Research62025
ZIAHG000024Genetic analysis of type II diabetes62025
P30DK017047Diabetes Research Center52025
P30DK056350Nutrition Obesity Research Center (NORC)52025

1 to 10 of 1,707Source NIH's project files

See all 1,707 nih grants

Papers2,376

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Erratum.Kidney Blood Press Res202642814674PubTator, text miningPubMed
Multivariate Genome-Wide Association Analysis Identifies Genetic Susceptibility Loci for Metabolic Syndrome in the Korean Genome and Epidemiology Study.Int J Mol Sci202642794471PubTator, text miningPubMed
Dietary Patterns Are Key Predictors of Cardiovascular Risk Beyond Genetic Risk Across Metabolic Syndrome Trajectories in A Korean Prospective Cohort Study.J Nutr202642772683PubTator, text miningPubMed
ADRB3, LEPR, FTO and PPARG variants contribute to obesity-related metabolic syndrome in Brazilian adults: a polygenic risk score approach.Int J Obes (Lond)202642768086PubTator, text miningPubMed
Clinical and functional evidence supporting pathogenicity of a novel APOA5 variant in familial chylomicronemia syndrome.Arch Endocrinol Metab202642721061PubTator, text miningPubMed
Retraction of: APOA5 alleviates reactive oxygen species to promote oxaliplatin resistance in PIK3CA-mutated colorectal cancer.Aging (Albany NY)202642641125PubTator, text miningPubMed
Utility of clinical scoring systems, laboratory, and genetic testing for appropriate classification of patients with severe hypertriglyceridemia in a Latin American cohort.J Clin Lipidol202642527267PubTator, text miningPubMed
Cross-Ancestry Proteogenomic Analyses Identified New Therapeutic Insights for Ischemic Heart Disease.J Am Coll Cardiol202642524807PubTator, text miningPubMed
Genetic determinants of chylomicronemia in Taiwan: Predominance of LPL rare variants and APOA5 p.G185C.J Clin Lipidol202642509091PubTator, text miningPubMed
Multifactorial Chylomicronemia Syndrome With a Rare APOA5 Variant and Recurrent Acute Pancreatitis: A Case Report From Rural Colombia.Cureus202642460225PubTator, text miningPubMed

1 to 10 of 2,376

See all 2,376 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/116519

GET https://conductscience.org/api/genes/v1/116519/patents?page=2