Gene · 116844
LRG1: leucine rich alpha-2-glycoprotein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LRG1: leucine rich alpha-2-glycoprotein 1. Genes, record 116844. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/116844
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P02750 | Leucine-rich alpha-2-glycoprotein | 347 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents102
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025172069 A | 2025-11-20 | 522 | P02750 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4152 | P02750 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8003 | P02750 | Espacenet |
| JP 2025138725 A | 2025-09-25 | 2062 | P02750 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6920 | P02750 | Espacenet |
| JP 2025118850 A | 2025-08-13 | 2 | P02750 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6920 | P02750 | Espacenet |
| EP 4587839 A2 | 2025-07-23 | 48 | P02750 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4152 | P02750 | Espacenet |
| EP 4549941 A1 | 2025-05-07 | 12 | P02750 | Espacenet |
1 to 10 of 102
See all 102 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants778
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LRG1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 5 | 2025 |
| U01CA200468 | Clinical Validation Center for Early Detection of Pancreatic Cancer | 5 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 3 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 2 | 2025 |
| P30CA043703 | Case Comprehensive Cancer Center Support Grant | 2 | 2025 |
| R01CA222349 | Non-canonical Caspase-8 Activation on Autophagosomal Membranes | 2 | 2025 |
| R01CA254036 | Urine and serum biomarkers for early diagnosis and risk assessment of pancreatic cancer | 2 | 2025 |
1 to 10 of 778Source NIH's project files
See all 778 nih grantsPapers1,817
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Maternal cardiovascular, endothelial and inflammatory biomarker dysregulation in twin-twin transfusion syndrome: insights into shared mechanisms with pre-eclampsia. | Placenta | 2026 | 42801806 | PubTator, text mining | PubMed |
| Diagnostic Performance of Serum Leucine-Rich Alpha-2-Glycoprotein 1 and Plasma Calprotectin in Adults with Suspected Acute Appendicitis: A Cross-Sectional Observational Study. | Biomedicines | 2026 | 42792764 | PubTator, text mining | PubMed |
| EVA1B promotes non-small cell lung cancer progression through an LRG1-associated mechanism. | 3 Biotech | 2026 | 42781045 | PubTator, text mining | PubMed |
| Evaluation of GCF levels of leucine-rich alpha-2 glycoprotein and TNF-α in stage III periodontitis patients: A case-control study. | J Oral Biol Craniofac Res | 2026 | 42775077 | PubTator, text mining | PubMed |
| Leucine-rich alpha-2 glycoprotein as a predictor of primary non-response to anti-TNF-α therapy in biologic-naïve Egyptian IBD patients. | BMC Gastroenterol | 2026 | 42760552 | PubTator, text mining | PubMed |
| Serum amyloid a as a high-resolution indicator of mucosal healing in ulcerative colitis. | Crohns Colitis 360 | 2026 | 42732310 | PubTator, text mining | PubMed |
| Anti-TNF therapy attenuates the diagnostic utility of leucine-rich α2-Glycoprotein 1 for endoscopic activity in ulcerative colitis. | Ther Adv Gastroenterol | 2026 | 42729529 | PubTator, text mining | PubMed |
| Serum Leucine-Rich α2-Glycoprotein 1 Identifies Cachexia in Patients With Liver Cirrhosis and/or Hepatocellular Carcinoma Having Low C-Reactive Protein Levels. | Hepatol Res | 2026 | 42723464 | PubTator, text mining | PubMed |
| Plasma protein profile in patients with antiphospholipid syndrome and controls without antiphospholipid syndrome. | J Thromb Haemost | 2026 | 42674367 | PubTator, text mining | PubMed |
| Polyp Tissue LRG1 Protein Levels and Helicobacter pylori Infection as Independent Predictors for Colonic Polyp Recurrence. | Int J Gen Med | 2026 | 42631196 | PubTator, text mining | PubMed |
1 to 10 of 1,817
See all 1,817 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/116844
GET https://conductscience.org/api/genes/v1/116844/patents?page=2