Gene · 117
ADCYAP1R1: ADCYAP receptor type I
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ADCYAP1R1: ADCYAP receptor type I. Genes, record 117. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/117
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P41586 | Pituitary adenylate cyclase-activating polypeptide type I receptor | 468 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36711 | P41586 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4431 | P41586 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 407 | P41586 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 295 | P41586 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5407 | P41586 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 295 | P41586 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5407 | P41586 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4431 | P41586 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 2838 | P41586 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24093 | P41586 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,151
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ADCYAP1R1 papers | Newest fiscal year |
|---|---|---|---|
| ZIADK053101 | Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors | 11 | 2025 |
| ZIAMH002386 | Chemical Coding of Neurotransmission | 11 | 2025 |
| R01MH108665 | Cell Type Specific Genomic and Functional Dissection of Fear-Off Amygdala Pathways | 8 | 2025 |
| ZIADK053100 | Characterization And Pharmacology Of Receptors For Gastrointestinal Peptides | 6 | 2025 |
| T32MH020030 | ResearchTraining: Psychiatric and Statistical Genetics | 5 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 4 | 2025 |
| R01HL131836 | Structural Transition of Cellular Integrins and Applications Thereof | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| K12HD052892 | Molecular Basis of Pediatric Disease | 3 | 2025 |
| R01HL101972 | Characterization of Coagulation Factor-platelet Interactions: Role of FXI | 3 | 2025 |
1 to 10 of 1,151Source NIH's project files
See all 1,151 nih grantsPapers1,829
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Structural basis of β-arrestin coupling and transducer selectivity in PAC1R. | Acta Pharmacol Sin | 2026 | 42706324 | PubTator, text mining | PubMed |
| Substance P and PACAP activate dural mast cells through MRGPRX2, not NK1R or PAC1/VPAC receptors. | Cephalalgia | 2026 | 42627518 | PubTator, text mining | PubMed |
| Pituitary adenylate cyclase-activating polypeptide and mitochondrial homeostasis in neuronal injury: mechanisms and translational prospects. | Front Immunol | 2026 | 42614376 | PubTator, text mining | PubMed |
| Diabetes Type 2: Circulating Phosphatidylserine-Expressing Platelets Regulate Whole Blood Agonist-Evoked Platelet Activity In Vitro. | TH Open | 2026 | 42592371 | PubTator, text mining | PubMed |
| [Pituitary adenylate-cyclase activating polypeptide (PACAP)-targeting treatment as a potential migraine prophylactic therapy]. | Ideggyogy Sz | 2026 | 42554332 | PubTator, text mining | PubMed |
| Methodological Considerations in Platelet Flow Cytometric Studies. | Int J Lab Hematol | 2026 | 42464905 | PubTator, text mining | PubMed |
| Diabetes type 2: magnitudes of agonist-evoked platelet activity markers in vitro demonstrate a substantial individual dependence. | Blood Coagul Fibrinolysis | 2026 | 42130232 | PubTator, text mining | PubMed |
| The pituitary adenylate cyclase-activating polypeptide receptor and its splice variants: Unique roles in affective and motivated behavior. | J Neuroendocrinol | 2026 | 41980614 | PubTator, text mining | PubMed |
| Novel small-molecule positive allosteric modulator 1 with blood-brain barrier penetration activity exerts anti-cellular senescence effects via the PAC1-R/YY1/SIRT6 pathway. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 41863098 | PubTator, text mining | PubMed |
| Impact of recalcification on procoagulant collagen-and-thrombin-activated (COAT) platelet generation in platelet-rich plasma samples with low platelet counts. | Res Pract Thromb Haemost | 2026 | 41810334 | PubTator, text mining | PubMed |
1 to 10 of 1,829
See all 1,829 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/117
GET https://conductscience.org/api/genes/v1/117/patents?page=2