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Gene · 1178

CLC: Charcot-Leyden crystal galectin

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CLC: Charcot-Leyden crystal galectin. Genes, record 1178. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1178

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Gene

Symbol
CLC
HGNC
Name
Charcot-Leyden crystal galectin
HGNC
NCBI Gene ID
1178
NCBI Gene
HGNC ID
HGNC:2014
HGNC
Ensembl
ENSG00000105205
NCBI Gene
Aliases
GAL10, Gal-10, LGALS10, LGALS10A, LPPL_HUMAN, MGC149659
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q05315Galectin-1014247Ensembl, GeneID, HGNC

Source UniProt

Patents44

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440963Q05315Espacenet
EP 4641202 A22025-10-294340Q05315Espacenet
WO 2025093745 A12025-05-08218Q05315Espacenet
KR 1020250017231 A2025-02-044340Q05315Espacenet
KR 1020240133723 A2024-09-049Q05315Espacenet
US 12006548 B22024-06-11560Q05315Espacenet
US 11713354 B22023-08-01141Q05315Espacenet
US 11446398 B22022-09-2014478Q05315Espacenet
US 11319374 B22022-05-0317Q05315Espacenet
JP 2022524081 A2022-04-27117449Q05315Espacenet

1 to 10 of 44

See all 44 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,037

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCLC papersNewest fiscal year
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease132025
U19AI070235Epithelial Genes in Allergic Inflammation72025
ZIAAI001130Eosinophils and Eosinophil Activation in the Pathogenesis of Human Disease72025
R01DK051610Structure-function analysis of the volume-regulated anion channel VRAC using novel LRRC8 chimeras52025
R01AI124355Genetic and Immunological Dissection of Eosinophilic Esophagitis42025
U2CTR002818Data Management and Coordinating Center: Rare Diseases Clinical Research Network42025
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition42025
P30CA008748Cancer Center Support Grant32025
R01AI145108The Role of Donor-Derived Eosinophils on Lung Allograft Ischemia Reperfusion Injury32025
T32AI083216Northwestern University Allergy and Immunology Research (NUAIR) Program32025

1 to 10 of 1,037Source NIH's project files

See all 1,037 nih grants

Papers1,896

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Galectin-10 and Charcot-Leyden Crystals in Chronic Rhinosinusitis with Nasal Polyps: Pathogenetic Insights and Clinical Implications.Diagnostics (Basel)202642739167PubTator, text miningPubMed
Blood Eosinophil Subtype-Specific Protein Gene Expression and Eosinophil-Derived Serum Mediators in Allergic Asthma Patients After Bronchial Challenge with Dermatophagoides pteronyssinus.Cells202642738872PubTator, text miningPubMed
Construction of a new predictive model in head and neck squamous cell carcinoma based on the investigation of extracellular matrix-associated genes.Oncol Lett202642729829PubTator, text miningPubMed
Association between pain and sarcopenia in middle-aged and older adults: a systematic review and meta-analysis.Front Public Health202642676468PubTator, text miningPubMed
Wavelength- and Helicity-Reconfigurable Circularly Polarized Optical Diodes Enabled by Molecular Photoswitches.Adv Mater202642671277PubTator, text miningPubMed
Tip funnel-shaped nanochannels sensor for high-flux chloride transport inspired by CLC.Anal Chim Acta202642618088PubTator, text miningPubMed
Impact of IL-5 Pathway Inhibition on Circulating Eosinophil- and Remodeling-Related Biomarkers in Severe Eosinophilic Asthma.J Asthma Allergy202642609892PubTator, text miningPubMed
Eosinophil-associated intestinal immune responses following SARS-CoV-2 infection in K18-hACE2 mice.PLoS One202642585251PubTator, text miningPubMed
A mitochondria-related 9-gene induced sputum signature for severe asthma: an integrative transcriptomic analysis with external validation.J Asthma202642535964PubTator, text miningPubMed
Current Clinical Perspectives of Biomarkers in Respiratory Diseases: A Narrative Review.J Clin Med202642513625PubTator, text miningPubMed

1 to 10 of 1,896

See all 1,896 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1178

GET https://conductscience.org/api/genes/v1/1178/patents?page=2