ConductScience.org, home

Gene · 118471

PRAP1: proline rich acidic protein 1

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. PRAP1: proline rich acidic protein 1. Genes, record 118471. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/118471

On this page

Gene

Symbol
PRAP1
HGNC
Name
proline rich acidic protein 1
HGNC
NCBI Gene ID
118471
NCBI Gene
HGNC ID
HGNC:23304
HGNC
Ensembl
ENSG00000165828
NCBI Gene
Aliases
PRO1195, UPA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96NZ9Proline-rich acidic protein 11510Ensembl, GeneID, HGNC

Source UniProt

Patents31

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1459230Q96NZ9Espacenet
EP 4650780 A22025-11-1913993Q96NZ9Espacenet
JP 2025147176 A2025-10-0610723Q96NZ9Espacenet
JP 2025529142 A2025-09-047416Q96NZ9Espacenet
US 12371689 B22025-07-297416Q96NZ9Espacenet
JP 2025517970 A2025-06-1213993Q96NZ9Espacenet
JP 2025028160 A2025-02-2810723Q96NZ9Espacenet
KR 1020250010750 A2025-01-2110723Q96NZ9Espacenet
EP 4487869 A22025-01-08499Q96NZ9Espacenet
JP 2024109657 A2024-08-1410730Q96NZ9Espacenet

1 to 10 of 31

See all 31 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants689

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePRAP1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant82025
R01AI137168Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis72025
K23HL151876Necroinflammatory Cell Death in Sepsis42025
R01AG069901ADMINISTRATIVE SUPPLEMENT - TargetAD: A systems multi-omics approach to drug repositioning in Alzheimer's disease42025
P30CA016058Cancer Center Support Grant32025
P30CA225520Stephenson Cancer Center - Cancer Center Support Grant32025
R01AI124491NLRP1 and CARD8 Inflammasomes: Assembly, Regulation and Stress Sensing32025
ZIAAI000810Vector-Borne Diseases: Biology Of Vector Host Relationship32025
P20GM103446Delaware INBRE22025
P30CA013148Comprehensive Cancer Center Support Grant22025

1 to 10 of 689Source NIH's project files

See all 689 nih grants

Papers1,405

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Transcriptomic trajectory of hepatocyte ballooning reveals a lipotoxic point of no return and initiates oncogenic regulatory rewiring in MASLD.Biochem Biophys Rep202642765067PubTator, text miningPubMed
Magnocurarine inhibits migration and invasion by suppressing mesenchymal marker expression and MAPK signaling in castration-resistant prostate cancer cells.Front Pharmacol202642741420PubTator, text miningPubMed
Patterned ELR-Gelatin Hydrogels Enable Rapid Endothelial Monolayer Formation via Bioactive Matrix Chemistry and Surface Topography.Adv Healthc Mater202642576392PubTator, text miningPubMed
Immune dysregulation drives the relapse of peritoneal dialysis-associated peritonitis: a single-center prospective study.Front Immunol202642490785PubTator, text miningPubMed
Transgene sequence codon optimization and composition determines replication competence of self-amplifying RNA.Mol Ther202642421318PubTator, text miningPubMed
Serum inflammatory proteomic signatures define chronic inflammatory demyelinating polyneuropathy and inform on disease activity.EBioMedicine202642349252PubTator, text miningPubMed
[Retracted] Downregulation of uPA/uPAR inhibits intermittent hypoxia‑induced epithelial‑mesenchymal transition (EMT) in DAOY and D283 medulloblastoma cells.Int J Oncol202642272242PubTator, text miningPubMed
Molecular and Pathophysiological Mechanisms Underlying Chronic Subdural Hematoma Recurrence: A Comprehensive Review.Neuromolecular Med202642271100PubTator, text miningPubMed
Antibody-conjugated species-sorted single-walled carbon nanotubes for multiplexed cytokine sensing.Commun Mater202642221745PubTator, text miningPubMed
LEF1/NFE2L3/TACC1 axis activates the AKT-mTOR pathway to promote the progression of esophageal squamous cell carcinoma.J Thorac Dis202642182760PubTator, text miningPubMed

1 to 10 of 1,405

See all 1,405 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/118471

GET https://conductscience.org/api/genes/v1/118471/patents?page=2