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SERPINA3: serpin family A member 3

1 protein, 207 patents, 0 drugs, 0 trials, 2,309 NIH grants and 5,022 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSERPINA3HGNC
Nameserpin family A member 3HGNC
NCBI Gene ID12NCBI Gene
HGNC IDHGNC:16HGNC
EnsemblENSG00000196136NCBI Gene
AliasesAACT, ACT, GIG24, GIG25NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01011Alpha-1-antichymotrypsin42326Ensembl, GeneID, HGNCUniProt

Patents 207

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4808571 A12026-09-235P01011Espacenet
JP 2026004568 A2026-01-1463179P01011Espacenet
JP 2026004568 A2026-01-1463180P01011Espacenet
JP 2026004568 A2026-01-1463181P01011Espacenet
EP 4650780 A22025-11-1910988P01011Espacenet
EP 4641201 A22025-10-2911401P01011Espacenet
JP 2025147176 A2025-10-0612041P01011Espacenet
JP 2025147176 A2025-10-0612042P01011Espacenet
JP 2025147176 A2025-10-0612043P01011Espacenet
JP 2025529142 A2025-09-047678P01011Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2309

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P50CA092629SPORE in Prostate Cancer142,025NIH's project files
P30CA008748Cancer Center Support Grant132,025NIH's project files
P30CA006973Regional Oncology Research Center112,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study102,025NIH's project files
R28AA012725Brain Tissue Resource Center for Alcohol Research62,025NIH's project files
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)62,025NIH's project files
K24HL136852Mentored Patient-Oriented Research for Preventing ASCVD Events52,025NIH's project files
P30CA016672Cancer Center Support Grant52,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant52,025NIH's project files
P30CA068485Cancer Center Support Grant52,025NIH's project files

Papers 5022

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42801661PubTator, text miningPubMed
42781186PubTator, text miningPubMed
42777411PubTator, text miningPubMed
42768374PubTator, text miningPubMed
42743238PubTator, text miningPubMed
42737666PubTator, text miningPubMed
42719784PubTator, text miningPubMed
42677343PubTator, text miningPubMed
42651061PubTator, text miningPubMed
42619794PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license