Gene · 1201
CLN3: CLN3 lysosomal/endosomal transmembrane protein, battenin
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CLN3: CLN3 lysosomal/endosomal transmembrane protein, battenin. Genes, record 1201. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1201
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13286 | Battenin | 438 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents93
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 247 | Q13286 | Espacenet |
| JP 2026067851 A | 2026-04-21 | 257 | Q13286 | Espacenet |
| EP 4704920 A1 | 2026-03-11 | 14 | Q13286 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7783 | Q13286 | Espacenet |
| JP 2025138648 A | 2025-09-25 | 1 | Q13286 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1023 | Q13286 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1023 | Q13286 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7783 | Q13286 | Espacenet |
| US 12297447 B2 | 2025-05-13 | 1 | Q13286 | Espacenet |
| JP 2025514710 A | 2025-05-09 | 14 | Q13286 | Espacenet |
1 to 10 of 93
See all 93 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants736
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CLN3 papers | Newest fiscal year |
|---|---|---|---|
| ZICMH002961 | Neurodevelopmental and Behavioral Phenotyping | 5 | 2025 |
| P50HD103536 | University of Rochester Intellectual and Developmental Disabilities Research Center | 4 | 2025 |
| R01EY022356 | Molecular Basis of Human Visual System Disorders | 3 | 2025 |
| ZIAHD000910 | Childhood Neurodegenerative Lysosomal Storage Disorders | 3 | 2025 |
| ZIAHD009001 | Research Investigations of Cellular Stress in Development and Diseases | 3 | 2025 |
| ZIAHL000140 | Lysosomal Diseases | 3 | 2025 |
| ZIATR000018 | Drug Repurposing Screening for Rare and Neglected Diseases | 3 | 2025 |
| P01AG019724 | Frontotemporal Dementia: Genes, Images, and Emotions | 2 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 2 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 736Source NIH's project files
See all 736 nih grantsPapers1,287
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Key Reaction Mechanisms on ZnO during Vulcanization: A Study Based on Density Functional Theory Calculations and Supporting Experiments. | ACS Omega | 2026 | 42729752 | PubTator, text mining | PubMed |
| A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder. | Sci Transl Med | 2026 | 42647598 | PubTator, text mining | PubMed |
| High-resolution promoter interaction analysis implicates genes involved in activation of type 3 innate lymphoid cells in immune disease risk. | Nat Genet | 2026 | 42552386 | PubTator, text mining | PubMed |
| Thapsigargin-induced autophagic flux impairment and inflammation are potentiated by CLN3 deficiency and alleviated by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) in human ARPE-19 cells. | Biochem Biophys Res Commun | 2026 | 42308764 | PubTator, text mining | PubMed |
| Behavioral and emotional symptoms and quality of life in a national sample of individuals with CLN3 Batten disease. | Orphanet J Rare Dis | 2026 | 42277918 | PubTator, text mining | PubMed |
| Cognitive test performance in CLN3 Disease is associated with the CLN3 Staging System (CLN3SS). | medRxiv | 2026 | 42238422 | PubTator, text mining | PubMed |
| Mania in Juvenile Neuronal Ceroid Lipofuscinosis (CLN3 Disease): A Rare Neuropsychiatric Presentation in an Adolescent. | J Child Neurol | 2026 | 42153457 | PubTator, text mining | PubMed |
| PPARα and RXRα in the regulation of neuronal ceroid lipofuscinosis genes: implications for Batten disease therapy. | NeuroImmune Pharm Ther | 2026 | 42146023 | PubTator, text mining | PubMed |
| Toward Early Diagnosis and Therapeutic Discovery in CLN3 Disease: A Computational Biomarker Discovery Framework. | medRxiv | 2026 | 42145637 | PubTator, text mining | PubMed |
| Modeling CLN3 Batten disease in astrocytes reveals alterations in mitochondria homeostasis, fatty acid metabolism and oxidative stress response. | J Biomed Sci | 2026 | 42129767 | PubTator, text mining | PubMed |
1 to 10 of 1,287
See all 1,287 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1201
GET https://conductscience.org/api/genes/v1/1201/patents?page=2