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CYP2R1: cytochrome P450 family 2 subfamily R member 1
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Gene · 120227

Papers1,899

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,899

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TitleJournalYearPMIDFound bySource
Vitamin D metabolites, genetic variants, and risk of cardiovascular diseases among individuals with newly diagnosed type 2 diabetes: a prospective study.Food Funct202642751891PubTator, text miningPubMed
Association of CYP2R1 gene polymorphisms with type 2 diabetes mellitus in the Jordanian population.J Genet Eng Biotechnol202642749425PubTator, text miningPubMed
Association of rs10741657 polymorphism in CYP2R1 gene with apparently healthy vitamin-D deficient Pakistani subjects.J Pak Med Assoc202642703112PubTator, text miningPubMed
Intervention methods and influencing factors of vitamin D deficiency in Northeast China: a self-controlled trial and randomized controlled trial study.Front Nutr202642609231PubTator, text miningPubMed
Beyond VDR: Vitamin D Metabolism Genes in Tuberculosis Susceptibility, Immune Response and Implications for Diabetes Mellitus.Infect Drug Resist202642604156PubTator, text miningPubMed
Genetic determinants of response to vitamin D supplementation.Front Nutr202642528639PubTator, text miningPubMed
Global Genetic Variation in Circulating 25-Hydroxyvitamin D: A Systematic Review of GWAS Evidence Across Different Ancestral Groups.Nutrients202642451056PubTator, text miningPubMed
From the Vitamin D Paradox to Precision Nutrition: Targeted Supplementation, Assay Pitfalls, and Clinical Decision-Making.Curr Nutr Rep202642397501PubTator, text miningPubMed
Vitamin D-related genetic variants as predictive biomarkers for breast cancer in Jordanian women.Front Med (Lausanne)202642292230PubTator, text miningPubMed
Genetic association and computational analysis of CYP2R1 gene polymorphisms rs2060793 and rs12794714 with vitamin D deficiency and acute myocardial infarction in the Bangladeshi population: A case control study.
PLoS One202642247388PubTator, text miningPubMed
Common genetic variants in vitamin D metabolism-related genes affect gut microbiota diversity in postmenopausal women.Genes Nutr202642157060PubTator, text miningPubMed
Free Fatty acid-induced disruption of hepatic vitamin D metabolism impairs bone homeostasis in an in vitro 3D human liver-bone model.Arch Toxicol202642126543PubTator, text miningPubMed
Patulin Affects the Hydroxylation of Vitamin D by Downregulating 25-hydroxylase (CYP2R1) and 25-hydroxyvitamin D 1-alpha-hydroxylase (CYP27B1) Expression and Interfering Their Substrate Binding Sites.J Biochem Mol Toxicol202642085557PubTator, text miningPubMed
MASH associated lipotoxicity perturbs the expression of hepatic vitamin D bioactivating gene CYP2R1 in humans and mice.Biochem Biophys Res Commun202642061004PubTator, text miningPubMed
Comprehensive Multi-Omics Characterization of CYP2R1 as a Diagnostic and Functional Biomarker in Hepatocellular Carcinoma.Med Sci (Basel)202642029602PubTator, text miningPubMed
Prenatal Aflatoxin B1 Exposure: A Review of Pathogenesis and Impact on Fetal Skeletal Development and Ossification.Toxins (Basel)202641893545PubTator, text miningPubMed
Genetic and epigenetic determinants of vitamin D metabolism: nutrigenomic insights for precision nutrition.Front Nutr202641867683PubTator, text miningPubMed
Vitamin D and Health Outcomes: State-of-the-Art Review of Triangulated Evidence and Ongoing Controversies.Curr Nutr Rep202641849024PubTator, text miningPubMed
Genetic background of infantile hypophosphatemia: a narrative review.Transl Pediatr202641810186PubTator, text miningPubMed
Vitamin D deficiency and disease conditions relevant to: Orthopaedic translation.J Orthop Translat202641777703PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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