Gene · 1213
CLTC: clathrin heavy chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CLTC: clathrin heavy chain. Genes, record 1213. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1213
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q00610 | Clathrin heavy chain 1 | 1,675 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents80
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026094314 A | 2026-06-09 | 61 | Q00610 | Espacenet |
| JP 2026021360 A | 2026-02-10 | 152 | Q00610 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41629 | Q00610 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2688 | Q00610 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2269 | Q00610 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2269 | Q00610 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2688 | Q00610 | Espacenet |
| JP 2025041709 A | 2025-03-26 | 79 | Q00610 | Espacenet |
| US 12239743 B2 | 2025-03-04 | 1 | Q00610 | Espacenet |
| US 12239743 B2 | 2025-03-04 | 6 | Q00610 | Espacenet |
1 to 10 of 80
See all 80 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,119
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CLTC papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 25 | 2025 |
| R01DA012864 | Mechanisms and Cellular Function of Opioid Receptor Endocytosis | 15 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 10 | 2025 |
| R01DA014204 | Regulation of Dopamine Transporter by Trafficking | 9 | 2025 |
| P30CA069533 | OHSU Knight Cancer Institute | 6 | 2025 |
| P30CA142543 | UT Southwestern Medical Center Simmons Comprehensive Cancer Center | 6 | 2025 |
| ZIAHL006098 | Architecture and control of exocytosis and endocytosis in excitable cells | 6 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
1 to 10 of 2,119Source NIH's project files
See all 2,119 nih grantsPapers3,108
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Nuclear LC3 Interactome Profiling Identifies Clathrin Heavy Chain as a Mediator of Nuclear LC3 Translocation in Trabecular Meshwork Cells. | bioRxiv | 2026 | 42818117 | PubTator, text mining | PubMed |
| Cognitive Performance Under AI Advice: Development and Initial Validation of a CHC-Informed Assessment for Organizational Decision-Making. | J Intell | 2026 | 42783583 | PubTator, text mining | PubMed |
| Divergent microtubule-organizing center strategies in mammalian gametogenesis. | Trends Open | 2026 | 42761981 | PubTator, text mining | PubMed |
| Exploratory Small RNA Sequencing in Localized Versus Locally Advanced Prostate Cancer: Putative Roles of CLTC and CDK6 as Downstream Targets of Differentially Expressed MicroRNAs. | Pharmaceuticals (Basel) | 2026 | 42653639 | PubTator, text mining | PubMed |
| Ocular Nystagmus as the Initial Presenting Feature in a Patient with Complete CLTC Deletion: Expanding the Genotype-Phenotype Spectrum of CLTC-Related Disorder. | Genes (Basel) | 2026 | 42650121 | PubTator, text mining | PubMed |
| The absorption and endocytosis mechanism of flaxseed cyclic peptide CLQ is mediated by its binding to clathrin. | Food Res Int | 2026 | 42632707 | PubTator, text mining | PubMed |
| Annexin A2 facilitates Japanese encephalitis virus replication by regulating endocytosis and intracellular transport in PK15 cells. | Front Microbiol | 2026 | 42630443 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Primary Renal Perivascular Epithelioid Cell Tumor with CLTC::TFE3 Gene Fusion: A Rare Gene Fusion and Masquerading as Renal Cell Carcinoma. | Int J Surg Pathol | 2026 | 42523124 | PubTator, text mining | PubMed |
| Genomic regions exhibiting divergent DNA methylation patterns co-vary with loci associated with sexual signalling traits in a stick insect. | Philos Trans R Soc Lond B Biol Sci | 2026 | 42489664 | PubTator, text mining | PubMed |
1 to 10 of 3,108
See all 3,108 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1213
GET https://conductscience.org/api/genes/v1/1213/patents?page=2