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SP7: Sp7 transcription factor

1 protein, 26 patents, 0 drugs, 0 trials, 2,081 NIH grants and 5,791 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolSP7HGNC
NameSp7 transcription factorHGNC
NCBI Gene ID121340NCBI Gene
HGNC IDHGNC:17321HGNC
EnsemblENSG00000170374NCBI Gene
AliasesOI11, OI12, OSX, osterixNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q8TDD2Transcription factor Sp74310Ensembl, GeneID, HGNCUniProt

Patents 26

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1465018Q8TDD2Espacenet
JP 2026004568 A2026-01-1465019Q8TDD2Espacenet
JP 2025147176 A2025-10-0615680Q8TDD2Espacenet
JP 2025028160 A2025-02-2815680Q8TDD2Espacenet
KR 1020250010750 A2025-01-2115680Q8TDD2Espacenet
JP 2024109657 A2024-08-1415519Q8TDD2Espacenet
US 11813308 B22023-11-1465Q8TDD2Espacenet
US 11446398 B22022-09-2082670Q8TDD2Espacenet
US 11446398 B22022-09-2082672Q8TDD2Espacenet
JP 2022524081 A2022-04-27185641Q8TDD2Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2081

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant222,025NIH's project files
P30AR069620Michigan Integrative Musculoskeletal Health Core Center (Overall Application)92,025NIH's project files
P30AR069619Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application)72,025NIH's project files
P30AR074992RESOURCE BASED CENTER FOR MUSCULOSKELETAL BIOLOGY AND MEDICINE72,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)72,025NIH's project files
R01AR048139Role and Mechanism of Action of Ksr2, an Obesity and Type 2 Diabetes Gene, in Bone Metabolism72,025NIH's project files
ZIADE000380The role of stem cells in skeletal health and disease72,025NIH's project files
R01DE019802DSPP signaling in dentinogenesis62,025NIH's project files
T32AR060719Skeletal Disorders Training Program62,025NIH's project files
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health62,025NIH's project files

Papers 5791

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42802956PubTator, text miningPubMed
42793064PubTator, text miningPubMed
42789062PubTator, text miningPubMed
42761843PubTator, text miningPubMed
42702121PubTator, text miningPubMed
42695483PubTator, text miningPubMed
42692731PubTator, text miningPubMed
42677438PubTator, text miningPubMed
42662722PubTator, text miningPubMed
42645254PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license