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Gene · 123

PLIN2: perilipin 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PLIN2: perilipin 2. Genes, record 123. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/123

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Gene

Symbol
PLIN2
HGNC
Name
perilipin 2
HGNC
NCBI Gene ID
123
NCBI Gene
HGNC ID
HGNC:248
HGNC
Ensembl
ENSG00000147872
NCBI Gene
Aliases
ADFP, ADRP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99541Perilipin-24370Ensembl, GeneID, HGNC

Source UniProt

Patents54

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457349Q99541Espacenet
EP 4650780 A22025-11-192983Q99541Espacenet
JP 2025517970 A2025-06-122983Q99541Espacenet
JP 2024509935 A2024-03-0542Q99541Espacenet
US 11694765 B22023-07-0498Q99541Espacenet
US 11446398 B22022-09-2061935Q99541Espacenet
JP 2022537339 A2022-08-25131Q99541Espacenet
JP 2022524081 A2022-04-27164906Q99541Espacenet
US 11078247 B22021-08-038615Q99541Espacenet
US 10987431 B22021-04-276Q99541Espacenet

1 to 10 of 54

See all 54 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,013

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePLIN2 papersNewest fiscal year
P30DK019525University of Pennsylvania Diabetes Research Center122025
P30DK048520Colorado Nutrition Obesity Research Center112025
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases112025
P30DK020572Michigan Diabetes Research Center (MDRC)102025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology102025
ZIABC005708Xenobiotic metabolism, cancer chemoprevention and cancer biomarkers102025
P30DK056338Texas Medical Center Digestive Diseases Center92025
R01AA020735Altered Lipid Droplet Trafficking: Role in Alcoholic Fatty Liver Disease92025
P30CA008748Cancer Center Support Grant82025
P30DK056341Washington University Nutrition Obesity Research Center82025

1 to 10 of 2,013Source NIH's project files

See all 2,013 nih grants

Papers3,599

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
In silico transcriptomic analysis nominates TSPAN32 as a central node of SCFA-driven immunometabolic reprogramming in intestinal epithelial cells.Front Bioinform202642774375PubTator, text miningPubMed
Lipid droplet-mitochondria contact sites as druggable spatial-pharmacology targets in respiratory disease: cross-cell-type mechanisms and translational strategies.Front Cell Dev Biol202642769092PubTator, text miningPubMed
Identification of TIPARP, BCL6 and PLIN2 as Potential Ferroptosisrelated Biomarkers for Osteoarthritis.Curr Med Chem202642736660PubTator, text miningPubMed
Quercetin attenuates polyethylene terephthalate nanoplastic-induced malignant phenotypes linked to APOE stabilization and lipid metabolic reprogramming in prostate cancer.Bioorg Chem202642721524PubTator, text miningPubMed
METTL3 Promotes Lipid Deposition and Pulmonary Fibrosis by Destabilizing PLIN2 in a m6A-Dependent Manner.J Cell Mol Med202642717476PubTator, text miningPubMed
Primary Cutaneous Apocrine Carcinoma: Clinicopathologic, Immunohistochemical, and Molecular Characterization of 27 Cases.Mod Pathol202642705610PubTator, text miningPubMed
Integrated histopathology and single-cell transcriptomics reveal distinct pathological features and foamy macrophage characteristics in spinal tuberculosis and brucellar spondylitis.Front Immunol202642698543PubTator, text miningPubMed
Liquiritigenin Ameliorates High-Fat Diet-Induced Hepatic Steatosis by Promoting Lipid Droplet Catabolism via PLIN2-ATGL Regulation.Phytother Res202642675379PubTator, text miningPubMed
Di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate upregulate PPARG and induce metabolic reprogramming in hepatocellular carcinoma cells: a pan-cancer and metabolomics study.Food Chem Toxicol202642674152PubTator, text miningPubMed
Machine learning-based classification model to distinguish tumor and tumor-free samples using synthetic plasma proteomic dataset.Clin Ter202642664122PubTator, text miningPubMed

1 to 10 of 3,599

See all 3,599 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/123

GET https://conductscience.org/api/genes/v1/123/patents?page=2