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CCR4: C-C motif chemokine receptor 4

1 protein, 195 patents, 1 drug, 31 trials, 4,922 NIH grants and 9,456 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCCR4HGNC
NameC-C motif chemokine receptor 4HGNC
NCBI Gene ID1233NCBI Gene
HGNC IDHGNC:1605HGNC
EnsemblENSG00000183813NCBI Gene
AliasesCC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5, k5-5NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P51679C-C chemokine receptor type 43607Ensembl, GeneID, HGNCUniProt

Patents 195

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026170016 A12026-08-1311P51679Espacenet
EP 4724076 A22026-04-1574P51679Espacenet
JP 2026062654 A2026-04-1025P51679Espacenet
JP 2026510989 A2026-04-1019P51679Espacenet
JP 2026004568 A2026-01-1441051P51679Espacenet
WO 2025259871 A12025-12-1821P51679Espacenet
EP 4641201 A22025-10-295714P51679Espacenet
EP 4641202 A22025-10-29322P51679Espacenet
JP 2025535503 A2025-10-2447P51679Espacenet
JP 2025147176 A2025-10-0616650P51679Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
MOGAMULIZUMABCHEMBL1743041C-C chemokine receptor type 4 cross-linking agentCROSS-LINKING AGENTChEMBL

Trials 31

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07529405MOGAMULIZUMABPHASE2ClinicalTrials.gov
NCT07132567MOGAMULIZUMABClinicalTrials.gov
NCT06285370MOGAMULIZUMABPHASE4ClinicalTrials.gov
NCT06235281MOGAMULIZUMABEARLY_PHASE1ClinicalTrials.gov
NCT05996185MOGAMULIZUMABPHASE2ClinicalTrials.gov
NCT05956041MOGAMULIZUMABPHASE2ClinicalTrials.gov
NCT05414500MOGAMULIZUMABPHASE1ClinicalTrials.gov
NCT04930653MOGAMULIZUMABPHASE2ClinicalTrials.gov
NCT04848064MOGAMULIZUMABPHASE1ClinicalTrials.gov
NCT04745234MOGAMULIZUMABPHASE2ClinicalTrials.gov

NIH grants 4922

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant452,025NIH's project files
P30CA016672Cancer Center Support Grant232,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital162,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success152,025NIH's project files
P01CA100730Retrovirus Models of Cancer132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P30CA047904Cancer Center Support Grant122,025NIH's project files
P30CA068485Cancer Center Support Grant112,025NIH's project files
P50CA126752SPORE in Lymphoma112,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant102,025NIH's project files

Papers 9456

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825902PubTator, text miningPubMed
42808572PubTator, text miningPubMed
42801782PubTator, text miningPubMed
42774230PubTator, text miningPubMed
42755361PubTator, text miningPubMed
42738870PubTator, text miningPubMed
42710064PubTator, text miningPubMed
42694111PubTator, text miningPubMed
42687902PubTator, text miningPubMed
42645607PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license