Gene · 1237
CCR8: C-C motif chemokine receptor 8
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CCR8: C-C motif chemokine receptor 8. Genes, record 1237. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1237
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51685 | C-C chemokine receptor type 8 | 355 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents167
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026170016 A1 | 2026-08-13 | 1 | P51685 | Espacenet |
| EP 4778939 A1 | 2026-07-22 | 81 | P51685 | Espacenet |
| US 12655223 B2 | 2026-06-16 | 2 | P51685 | Espacenet |
| JP 2026515899 A | 2026-05-19 | 37 | P51685 | Espacenet |
| WO 2026100725 A | 2026-05-15 | 1 | P51685 | Espacenet |
| EP 4722248 A1 | 2026-04-08 | 83 | P51685 | Espacenet |
| EP 4705346 A2 | 2026-03-11 | 37 | P51685 | Espacenet |
| JP 2026507758 A | 2026-03-06 | 12 | P51685 | Espacenet |
| WO 2026019990 A1 | 2026-01-22 | 22 | P51685 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41060 | P51685 | Espacenet |
1 to 10 of 167
See all 167 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,226
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CCR8 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 11 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 9 | 2025 |
| P30AR069625 | Human Skin Disease Resource-based Center | 4 | 2025 |
| ZIAAI000615 | Molecular Analysis Of Leukocyte Activation By Chemoattractants | 4 | 2025 |
| P01CA019014 | Viral Oncogenesis, Latency, and Replication | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 3 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 3 | 2025 |
| R01AI123349 | Cellular mechanisms by which exhausted T cell responses are restored | 3 | 2025 |
| T32AI007290 | Molecular and Cellular Immunobiology | 3 | 2025 |
1 to 10 of 1,226Source NIH's project files
See all 1,226 nih grantsPapers2,300
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Immunometabolic Profiling of T Cells and Innate Lymphoid Cells Uncovers Therapeutic Targets to Enhance Immunotherapy in Head and Neck Cancer. | Cancer Immunol Res | 2026 | 42804348 | PubTator, text mining | PubMed |
| Spatial Treg niches and the therapeutic reprogramming of tumour tolerance in cancer. | Front Cell Dev Biol | 2026 | 42769030 | PubTator, text mining | PubMed |
| Molecular heterogeneity and clonal origin of CCR8+ effector regulatory T cells in human cancer. | Nat Commun | 2026 | 42764351 | PubTator, text mining | PubMed |
| Semi-Mechanistic Modeling of S-531011, a Humanized Anti-CCR8 Monoclonal Antibody, for Prediction of CCR8 Receptor Occupancy in Human Tumor Tissues. | CPT Pharmacometrics Syst Pharmacol | 2026 | 42689490 | PubTator, text mining | PubMed |
| Nonpathogenic SIV Infection in Sooty Mangabeys Is Characterized by a Lack of Activation and Expansion of Monocytes. | J Med Primatol | 2026 | 42596509 | PubTator, text mining | PubMed |
| Tape-strip transcriptomics identify immune signatures in cutaneous T-cell lymphoma distinct from benign inflammatory skin diseases. | J Allergy Clin Immunol | 2026 | 42567485 | PubTator, text mining | PubMed |
| Leukocyte-Rich Platelet-Rich Plasma (L-PRP) Promotes Rejuvenation of Senescent Fibroblasts and Dermal Remodeling via CCL1-CCR8 Signaling and PKM2 Modulation. | Int J Mol Sci | 2026 | 42511624 | PubTator, text mining | PubMed |
| Next-generation precision oncology in microsatellite stable colorectal cancer: integrated targeting beyond RAS and RAF. | ESMO Open | 2026 | 42462280 | PubTator, text mining | PubMed |
| BLIMP-1 and CD39 expression define human effector memory regulatory T cells in blood and recall responses to viruses. | Immunol Cell Biol | 2026 | 42448314 | PubTator, text mining | PubMed |
| Selective Depletion of Tumor-Infiltrating CD4+CCR8+ Tregs by AZ084, a Novel CCR8 Antagonist. | Cancer Sci | 2026 | 42437746 | PubTator, text mining | PubMed |
1 to 10 of 2,300
See all 2,300 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1237
GET https://conductscience.org/api/genes/v1/1237/patents?page=2