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ADH1A: alcohol dehydrogenase 1A (class I), alpha polypeptide

1 protein, 23 patents, 2 drugs, 3 trials, 2,537 NIH grants and 4,740 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolADH1AHGNC
Namealcohol dehydrogenase 1A (class I), alpha polypeptideHGNC
NCBI Gene ID124NCBI Gene
HGNC IDHGNC:249HGNC
EnsemblENSG00000187758NCBI Gene
AliasesADH1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07327Alcohol dehydrogenase 1A3752Ensembl, GeneID, HGNCUniProt

Patents 23

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436965P07327Espacenet
EP 4641201 A22025-10-29211P07327Espacenet
JP 2025517969 A2025-06-12211P07327Espacenet
JP 2025062604 A2025-04-143781P07327Espacenet
US 11446398 B22022-09-203781P07327Espacenet
JP 2022524081 A2022-04-27106752P07327Espacenet
US 11078247 B22021-08-03275P07327Espacenet
US 10323232 B22019-06-1865P07327Espacenet
US 10323232 B22019-06-1866P07327Espacenet
JP 2019054813 A2019-04-11217400P07327Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
FOMEPIZOLECHEMBL1308Alcohol dehydrogenase class I inhibitorINHIBITORChEMBL
NITREFAZOLECHEMBL1909285Alcohol dehydrogenase inhibitorINHIBITORChEMBL

Trials 3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05517668FOMEPIZOLEPHASE2ClinicalTrials.gov
NCT00661141FOMEPIZOLEPHASE22017-09-15ClinicalTrials.gov
NCT00346853FOMEPIZOLEPHASE1ClinicalTrials.gov

NIH grants 2537

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).312,025NIH's project files
P60AA007611Center on Genetic Determinants of Alcohol Ingestion and Responses to Alcohol202,025NIH's project files
P50AA012870Center for the Translational Neuroscience of Alcoholism142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
P50AA022537Cross-species investigation of gene networks for ethanol-related behaviors112,025NIH's project files
ZIAAA000301Integrative genetics of behavior with high throughput technologies102,025NIH's project files
P30CA016672Cancer Center Support Grant92,025NIH's project files
P50AA011999Southern California Research Center for ALPD and Cirrhosis92,025NIH's project files
U01AI069924International epidemiology Databases to Evaluate AIDS (IeDEA) Southern Africa.92,025NIH's project files
P60AA006420CNS Effects of Alcohol: Cellular Neurobiology82,025NIH's project files

Papers 4740

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42801008PubTator, text miningPubMed
42787726PubTator, text miningPubMed
42766164PubTator, text miningPubMed
42759391PubTator, text miningPubMed
42719843PubTator, text miningPubMed
42718815PubTator, text miningPubMed
42650831PubTator, text miningPubMed
42588458PubTator, text miningPubMed
42571018PubTator, text miningPubMed
42565304PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license