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Gene · 1240

CMKLR1: chemerin chemokine-like receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CMKLR1: chemerin chemokine-like receptor 1. Genes, record 1240. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1240

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Gene

Symbol
CMKLR1
HGNC
Name
chemerin chemokine-like receptor 1
HGNC
NCBI Gene ID
1240
NCBI Gene
HGNC ID
HGNC:2121
HGNC
Ensembl
ENSG00000174600
NCBI Gene
Aliases
CHEMERINR, ChemR23, DEZ, ERV1, RVER1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99788Chemerin-like receptor 13734Ensembl, GeneID, HGNC

Source UniProt

Patents67

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441107Q99788Espacenet
JP 2026004568 A2026-01-1441109Q99788Espacenet
JP 2026004568 A2026-01-1441111Q99788Espacenet
EP 4656247 A22025-12-031Q99788Espacenet
EP 4641201 A22025-10-294347Q99788Espacenet
EP 4641202 A22025-10-29259Q99788Espacenet
JP 2025134864 A2025-09-171Q99788Espacenet
JP 2025529142 A2025-09-041035Q99788Espacenet
EP 4606428 A22025-08-2724Q99788Espacenet
US 12371689 B22025-07-291035Q99788Espacenet

1 to 10 of 67

See all 67 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants830

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCMKLR1 papersNewest fiscal year
T32AI007290Molecular and Cellular Immunobiology102025
R01AI047822Intestinal Lymphocyte Trafficking82025
P30CA008748Cancer Center Support Grant52025
R35GM128641Structure, pharmacology and signaling of G protein-coupled receptors (GPCRs) in inflammation42025
I01BX004115New Approaches to Combat CNS Inflammation: Targeting a Metabolic Enzyme in Demyelinating Disease32025
P30CA047904Cancer Center Support Grant32025
R01DK095491Indole dysbiosis and mucosal inflammation32025
UL1TR001863Yale Clinical and Translational Science Award32025
ZIAHL002345Allogeneic and Autologous Immunotherapy for cancer and nonmalignant hematological disorders32025
P30CA014599Cancer Center Support Grant22025

1 to 10 of 830Source NIH's project files

See all 830 nih grants

Papers1,391

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Chemerin - CMKLR1 signaling contributes to immune metabolic dysfunction in salt-sensitive hypertension.Clin Exp Hypertens202642802577PubTator, text miningPubMed
Combining pro-resolving therapy with cyclosporine A restores immune homeostasis and reduces toxicity in autoimmune bone marrow failure.Cell Rep Med202642785302PubTator, text miningPubMed
CXCR4+ circulating tumor cells (CTCs) accumulate in subcutaneous, immune suppressive, CXCL12-loaded-hydrogel.Mater Today Bio202642733769PubTator, text miningPubMed
Characterization of posttranslational modification in metabolic dysfunction-associated steatohepatitis: acetylation, lactylation, and phosphorylation.J Lipid Res202642537908PubTator, text miningPubMed
Protocol for studying Chemerin 15-enhanced microglial phagocytosis in cerebral ischemia-reperfusion injury via the ChemR23/p38 MAPK pathway.STAR Protoc202642490223PubTator, text miningPubMed
Coexpression of GITRL confers resistance to Treg cell-mediated immunosuppression to anti-CD19 CAR-NK cells.Front Immunol202642488650PubTator, text miningPubMed
Chemerin Normal Function and Roles in Metabolic and Nonmetabolic Disorders: An Up-To-Date Comprehensive Review.Biochem Res Int202642415929PubTator, text miningPubMed
Targeted, receptor-mediated delivery of a masked d-amino acid cell-penetrating peptide for cell-specific phototoxicity.FEBS J202642212778PubTator, text miningPubMed
Consistent Metabolomic and Genetic Evidence Supports Acisoga as a Key Contributor to Colorectal Neoplasia Progression.Cancer Epidemiol Biomarkers Prev202642201318PubTator, text miningPubMed
Erratum for the Research Article "The chemerin-CMKLR1 axis limits thermogenesis by controlling a beige adipocyte/IL-33/type 2 innate immunity circuit".Sci Immunol202642030374PubTator, text miningPubMed

1 to 10 of 1,391

See all 1,391 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1240

GET https://conductscience.org/api/genes/v1/1240/patents?page=2