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Gene · 126328

NDUFA11: NADH:ubiquinone oxidoreductase subunit A11

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NDUFA11: NADH:ubiquinone oxidoreductase subunit A11. Genes, record 126328. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/126328

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Gene

Symbol
NDUFA11
HGNC
Name
NADH:ubiquinone oxidoreductase subunit A11
HGNC
NCBI Gene ID
126328
NCBI Gene
HGNC ID
HGNC:20371
HGNC
Ensembl
ENSG00000174886
NCBI Gene
Aliases
B14.7, CI-B14.7, MC1DN14
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q86Y39NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 111417Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454918Q86Y39Espacenet
EP 4650780 A22025-11-194777Q86Y39Espacenet
JP 2025529142 A2025-09-042802Q86Y39Espacenet
US 12371689 B22025-07-292802Q86Y39Espacenet
JP 2025517970 A2025-06-124777Q86Y39Espacenet
US 11446398 B22022-09-2055013Q86Y39Espacenet
JP 2022524081 A2022-04-27157984Q86Y39Espacenet
JP 2019054813 A2019-04-11235353Q86Y39Espacenet
JP 2017121241 A2017-07-13235353Q86Y39Espacenet
JP 2015516143 A2015-06-08235353Q86Y39Espacenet

1 to 10 of 25

See all 25 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ME-344CHEMBL5314386Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMINCHEMBL1431Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMIN HYDROCHLORIDECHEMBL1703Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
NV-128CHEMBL3545135Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL

Trials1,218

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants359

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNDUFA11 papersNewest fiscal year
P30CA016672Cancer Center Support Grant32025
P2CHD050924Carolina Population Center22025
P30CA093373Cancer Center Support Grant P3022025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital22025
P30DK063491Diabetes Research Center (DRC)22025
P30ES007048Environmental Exposures, Host Factors and Human Disease22025
P40OD018537Bloomington Drosophila Stock Center at Indiana University22025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions12025
P01CA066996Development of Novel Therapeutic Strategies in Human Leukemias12025
P01CA229086The impact of changes in chromatin architecture on cancer phenotypes and tumor progression12025

1 to 10 of 359Source NIH's project files

See all 359 nih grants

Papers357

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Prognostic characteristics of disulfidptosis-related genes across cancers and their potential implications in osteosarcoma.Sci Prog202642370567PubTator, text miningPubMed
Disulfidptosis-related genes define a prognostic signature and novel therapeutic targets in Ewing's sarcoma through transcriptomic analysis and experimental validation.Front Immunol202642064080PubTator, text miningPubMed
Parkinson's Disease: From Metabolism to Genetics-A Comprehensive Review.Curr Issues Mol Biol202641899406PubTator, text miningPubMed
A genus-wide interaction atlas across NS4B orthologues identifies a conserved role for UFMylation in orthoflavivirus replication.Nat Commun202641826287PubTator, text miningPubMed
Mitochondrial abnormalities in idiopathic inflammatory myopathies.Clin Exp Rheumatol202641738252PubTator, text miningPubMed
Machine learning identifies disulfidptosis-related gene signature for pancreatic cancer prognosis and immune infiltration.Discov Oncol202641591656PubTator, text miningPubMed
Integrated proteomics and metabolomics reveal phytosesquiterpene lactones inhibit TNBC cell activity by depleting ATP synthesis and reprogramming primary metabolism.Sci Rep202641530404PubTator, text miningPubMed
Prediction of the Prognosis and Treatment Responses Based on the Characteristics of Disulfidptosis-Related Genes in Patients with Cervical Squamous Cell Carcinoma and Endocervical AdenocarcinomaEndocr Metab Immune Disord Drug Targets202639945255PubTator, text miningPubMed
Mitochondrial energy metabolism genes as prognostic biomarkers in clear cell renal cell carcinoma via single-cell and bulk RNA sequencing analyses.Discov Oncol202541364140PubTator, text miningPubMed
Molecular subtypes and prognostic signature rooted in disulfidptosis highlight tumor microenvironment in lung adenocarcinoma.Chin J Cancer Res202541246257PubTator, text miningPubMed

1 to 10 of 357

See all 357 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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