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Gene · 1264

CNN1: calponin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CNN1: calponin 1. Genes, record 1264. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1264

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Gene

Symbol
CNN1
HGNC
Name
calponin 1
HGNC
NCBI Gene ID
1264
NCBI Gene
HGNC ID
HGNC:2155
HGNC
Ensembl
ENSG00000130176
NCBI Gene
Aliases
HEL-S-14, SMCC, Sm-Calp
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51911Calponin-12971Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191384P51911Espacenet
JP 2025517970 A2025-06-121384P51911Espacenet
JP 2025062604 A2025-04-1411244P51911Espacenet
JP 2024109713 A2024-08-1414P51911Espacenet
KR 1020220148615 A2022-11-077P51911Espacenet
US 11473151 B22022-10-1814P51911Espacenet
US 11446398 B22022-09-2011244P51911Espacenet
JP 2022524081 A2022-04-27114215P51911Espacenet
US 11078247 B22021-08-032342P51911Espacenet
JP 2021502066 A2021-01-2838P51911Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,174

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCNN1 papersNewest fiscal year
R01HL134817Causal variant association mechanisms in TCF21 binding coronary disease loci82025
R01HL139478The SMAD3 signaling network in coronary artery disease risk72025
P30CA008748Cancer Center Support Grant52025
R01HL131017Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes42025
R01HL141371Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy42025
R01HL148239Multimodal genetic regulatory architecture of coronary artery disease42025
R01HL164577Functional genomics investigation of pleiotropic vascular disease loci42025
K01HL164687Novel molecular mechanisms of vascular smooth muscle cell-mediated large and small artery calcification32025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center32025
P51OD011092Support for National Primate Research Center32025

1 to 10 of 1,174Source NIH's project files

See all 1,174 nih grants

Papers1,467

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Robotic handling preserves iPSC-derived vascular smooth muscle cell differentiation.Mater Today Bio202642774489PubTator, text miningPubMed
Integrative transcriptomic identification of potential common biomarkers between non-obstructive azoospermia and papillary thyroid cancer via multi-algorithmic machine learning and network biology approaches.
Cancer Treat Res Commun202642710154PubTator, text miningPubMed
An Unusual Low-Grade Biphasic Pulmonary Neoplasm Harboring BRAF-V600E Mutation: A Potential Variant of Bronchiolar Adenoma.Int J Surg Pathol202642595357PubTator, text miningPubMed
GW0742 prevents neointima formation by upregulating FABP3 expression.Eur J Pharm Sci202642586383PubTator, text miningPubMed
An Integrative Transcriptomic, Network Pharmacology, and Molecular Docking Analysis of the Ferroptosis-Fibrosis Axis in Cardiomyopathy with Exploratory Relevance to Diabetic Cardiomyopathy.Biomedicines202642511975PubTator, text miningPubMed
Cdc42 small GTPase is a novel regulator of the fibrogenic activation of human intestinal myofibroblasts.bioRxiv202642465272PubTator, text miningPubMed
EphB4/EphrinB2 signaling regulates pericyte-like function of DPSCs in angiogenesis via transcriptional factor SRF.Stem Cell Res Ther202642298719PubTator, text miningPubMed
Histone lactylation modification promotes docetaxel resistance and tumor progression through CNN1-Mediated autophagy and cell cycle arrest in Castration-resistant prostate cancer.Cell Death Discov202642129130PubTator, text miningPubMed
Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor.Sci Adv202641931622PubTator, text miningPubMed
A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium.EBioMedicine202641875497PubTator, text miningPubMed

1 to 10 of 1,467

See all 1,467 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1264

GET https://conductscience.org/api/genes/v1/1264/patents?page=2