Gene · 1264
CNN1: calponin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CNN1: calponin 1. Genes, record 1264. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1264
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51911 | Calponin-1 | 297 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents21
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 1384 | P51911 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1384 | P51911 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 11244 | P51911 | Espacenet |
| JP 2024109713 A | 2024-08-14 | 14 | P51911 | Espacenet |
| KR 1020220148615 A | 2022-11-07 | 7 | P51911 | Espacenet |
| US 11473151 B2 | 2022-10-18 | 14 | P51911 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 11244 | P51911 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 114215 | P51911 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 2342 | P51911 | Espacenet |
| JP 2021502066 A | 2021-01-28 | 38 | P51911 | Espacenet |
1 to 10 of 21
See all 21 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,174
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CNN1 papers | Newest fiscal year |
|---|---|---|---|
| R01HL134817 | Causal variant association mechanisms in TCF21 binding coronary disease loci | 8 | 2025 |
| R01HL139478 | The SMAD3 signaling network in coronary artery disease risk | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01HL131017 | Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes | 4 | 2025 |
| R01HL141371 | Human iPSCs for Elucidating Intercellular Crosstalk Signaling in Dilated Cardiomyopathy | 4 | 2025 |
| R01HL148239 | Multimodal genetic regulatory architecture of coronary artery disease | 4 | 2025 |
| R01HL164577 | Functional genomics investigation of pleiotropic vascular disease loci | 4 | 2025 |
| K01HL164687 | Novel molecular mechanisms of vascular smooth muscle cell-mediated large and small artery calcification | 3 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 3 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 3 | 2025 |
1 to 10 of 1,174Source NIH's project files
See all 1,174 nih grantsPapers1,467
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Robotic handling preserves iPSC-derived vascular smooth muscle cell differentiation. | Mater Today Bio | 2026 | 42774489 | PubTator, text mining | PubMed |
Integrative transcriptomic identification of potential common biomarkers between non-obstructive azoospermia and papillary thyroid cancer via multi-algorithmic machine learning and network biology approaches. | Cancer Treat Res Commun | 2026 | 42710154 | PubTator, text mining | PubMed |
| An Unusual Low-Grade Biphasic Pulmonary Neoplasm Harboring BRAF-V600E Mutation: A Potential Variant of Bronchiolar Adenoma. | Int J Surg Pathol | 2026 | 42595357 | PubTator, text mining | PubMed |
| GW0742 prevents neointima formation by upregulating FABP3 expression. | Eur J Pharm Sci | 2026 | 42586383 | PubTator, text mining | PubMed |
| An Integrative Transcriptomic, Network Pharmacology, and Molecular Docking Analysis of the Ferroptosis-Fibrosis Axis in Cardiomyopathy with Exploratory Relevance to Diabetic Cardiomyopathy. | Biomedicines | 2026 | 42511975 | PubTator, text mining | PubMed |
| Cdc42 small GTPase is a novel regulator of the fibrogenic activation of human intestinal myofibroblasts. | bioRxiv | 2026 | 42465272 | PubTator, text mining | PubMed |
| EphB4/EphrinB2 signaling regulates pericyte-like function of DPSCs in angiogenesis via transcriptional factor SRF. | Stem Cell Res Ther | 2026 | 42298719 | PubTator, text mining | PubMed |
| Histone lactylation modification promotes docetaxel resistance and tumor progression through CNN1-Mediated autophagy and cell cycle arrest in Castration-resistant prostate cancer. | Cell Death Discov | 2026 | 42129130 | PubTator, text mining | PubMed |
| Selective vulnerability of cerebral vasculature to NOTCH3 variants in small vessel disease and rescue by phosphodiesterase-5 inhibitor. | Sci Adv | 2026 | 41931622 | PubTator, text mining | PubMed |
| A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium. | EBioMedicine | 2026 | 41875497 | PubTator, text mining | PubMed |
1 to 10 of 1,467
See all 1,467 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1264
GET https://conductscience.org/api/genes/v1/1264/patents?page=2