Gene · 128
ADH5: alcohol dehydrogenase 5 (class III), chi polypeptide
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ADH5: alcohol dehydrogenase 5 (class III), chi polypeptide. Genes, record 128. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/128
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P11766 | Alcohol dehydrogenase class-3 | 374 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36971 | P11766 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3716 | P11766 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 3300 | P11766 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 3300 | P11766 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3716 | P11766 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3797 | P11766 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 3797 | P11766 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 106768 | P11766 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 278 | P11766 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 82 | P11766 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials8
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT04600778 | CAVOSONSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT04129931 | CAVOSONSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT02724527 | CAVOSONSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT02589236 | CAVOSONSTAT | PHASE2 | ClinicalTrials.gov | |
| NCT02275936 | CAVOSONSTAT | PHASE1 | ClinicalTrials.gov | |
| NCT02227888 | CAVOSONSTAT | PHASE1 | ClinicalTrials.gov | |
| NCT01746784 | N6022 | PHASE1 | 2014-11-24 | ClinicalTrials.gov |
| NCT01316315 | N6022 | PHASE1/PHASE2 | 2014-03-11 | ClinicalTrials.gov |
NIH grants1,060
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ADH5 papers | Newest fiscal year |
|---|---|---|---|
| U10AA008401 | Collaborative Study on the Genetics of Alcoholism (COGA). | 18 | 2025 |
| P50AA012870 | Center for the Translational Neuroscience of Alcoholism | 9 | 2025 |
| P30DK026743 | UCSF Liver Center | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| P42ES004705 | Toxic substances in the environment | 4 | 2025 |
| R01DA054869 | 7/7 Psychiatric Genomics Consortium: Advancing Discovery and Impact | 4 | 2025 |
| R01ES028096 | Chemical Probes to Study Formaldehyde Biology | 4 | 2025 |
1 to 10 of 1,060Source NIH's project files
See all 1,060 nih grantsPapers1,451
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Functional and Compositional Shifts in Lung and Gut Microbiota after One Year of Treatment with Highly Effective CFTR Modulators in Cystic Fibrosis. | Arch Bronconeumol | 2026 | 42791132 | PubTator, text mining | PubMed |
| Immunomodulatory and anti-inflammatory potential of S-nitrosoglutathione (GSNO) in multiple sclerosis: a review of mechanisms and therapeutic perspectives. | Front Immunol | 2026 | 42688580 | PubTator, text mining | PubMed |
| Error-calibrated sensing: ratiometric biosensor for carcinogenic formaldehyde in food safety monitoring. | Food Chem | 2026 | 42685422 | PubTator, text mining | PubMed |
| HPCA1 and CaM3 contribute to peroxisomal H2O2-driven activation of salicylic acid responses. | Plant Physiol | 2026 | 42612176 | PubTator, text mining | PubMed |
| Unraveling the association between triclosan and breast cancer: A multidimensional research strategy integrating machine learning, mendelian randomization, and molecular dynamics simulations. | Environ Int | 2026 | 42594736 | PubTator, text mining | PubMed |
| Human Nasal and Bronchial Epithelium in Cystic Fibrosis: Differences in Expression of Airway pH Regulatory Proteins. | Pediatr Pulmonol | 2026 | 42591023 | PubTator, text mining | PubMed |
| Excess folate elevates formaldehyde genotoxicity in cell lines but not in mice or humans. | EMBO Mol Med | 2026 | 42587126 | PubTator, text mining | PubMed |
| Nuclear SOD1 links ATM-CHK2 signaling to ADH5/GSNOR transcription in SHSY-5Y SOD1G93A cellular models of ALS. | Nitric Oxide | 2026 | 42586199 | PubTator, text mining | PubMed |
| GNPs-pIL-4 reprograms macrophage polarization and activates the OSM/GSNOR/ENG axis to improve angiogenesis in ischemic limbs. | Sci Adv | 2026 | 42585315 | PubTator, text mining | PubMed |
| GSNOR reprograms nitrosylation to drive endothelial-to-mesenchymal transition and fibrotic vascular remodeling. | Redox Biol | 2026 | 42579926 | PubTator, text mining | PubMed |
1 to 10 of 1,451
See all 1,451 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/128
GET https://conductscience.org/api/genes/v1/128/patents?page=2