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Gene · 129607

CMPK2: cytidine/uridine monophosphate kinase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CMPK2: cytidine/uridine monophosphate kinase 2. Genes, record 129607. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/129607

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Gene

Symbol
CMPK2
HGNC
Name
cytidine/uridine monophosphate kinase 2
HGNC
NCBI Gene ID
129607
NCBI Gene
HGNC ID
HGNC:27015
HGNC
Ensembl
ENSG00000134326
NCBI Gene
Aliases
IBGC10, NDK, TMPK2, TYKi, UMP-CMPK2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q5EBM0UMP-CMP kinase 2, mitochondrial4490Ensembl, GeneID, HGNC

Source UniProt

Patents11

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442759Q5EBM0Espacenet
US 11617761 B22023-04-041Q5EBM0Espacenet
US 11446398 B22022-09-2021675Q5EBM0Espacenet
JP 2022524081 A2022-04-27124646Q5EBM0Espacenet
US 10869880 B22020-12-221Q5EBM0Espacenet
JP 2019054813 A2019-04-11223194Q5EBM0Espacenet
JP 2017121241 A2017-07-13223194Q5EBM0Espacenet
JP 2015516143 A2015-06-08223194Q5EBM0Espacenet
EP 2052088 A22009-04-297584Q5EBM0Espacenet
JP 2006516089 A2006-06-224141Q5EBM0Espacenet

1 to 10 of 11

See all 11 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,236

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCMPK2 papersNewest fiscal year
T32CA154274Training Grant in Cancer Biology82025
P30CA014195Cancer Center Support Grant (CCSG)52025
P20GM103436IDeA Networks of Biomedical Research Excellence in Kentucky32025
P30AI094189The Johns Hopkins Center for AIDS Research (JHU CFAR)32025
P30CA008748Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA091842Cancer Center Support Grant32025
P30CA134274UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT32025
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases32025
R01NS076511Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry32025

1 to 10 of 1,236Source NIH's project files

See all 1,236 nih grants

Papers1,751

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Nucleotide metabolic reprogramming: a "double-edged sword" in obesity-related inflammation-from metabolic adaptation to pathological imbalance.J Physiol Biochem202642799975PubTator, text miningPubMed
Interferome profiling in the blood links IFNα5-Mucin-1 axis to HIV-1 pathogenesis.J Virol202642788733PubTator, text miningPubMed
Recent insights on cell-type-specific lactylation driving neuropathic pain chronification.Neurochem Int202642648441PubTator, text miningPubMed
CCL20 Released by Drug-Tolerant Persisters Impairs Immunotherapy in EGFR-Mutant Lung Adenocarcinoma.MedComm (2020)202642549034PubTator, text miningPubMed
RSAD2/VIPERIN and CMPK2 coordinate an immunometabolic response to Epstein-Barr Virus.PLoS Pathog202642546073PubTator, text miningPubMed
Reconfiguration of the Microtubule Network and Dynamics in Hypoxic Cancer Cells.Chem Biomed Imaging202642529405PubTator, text miningPubMed
Functional and transcriptome analyses identify CMPK2 as a potential antiviral factor against NNV in Siniperca chuatsi.Dev Comp Immunol202642468658PubTator, text miningPubMed
Letter to editor: Mitochondrial DNA release contributes to neuropathic pain via a cGAS-STING-IRF3 CMPK2-associated immunometabolic feedback mechanism.J Transl Med202642458472PubTator, text miningPubMed
Identification of key metabolic enzymes involved in the activation of obeldesivir and remdesivir to the active triphosphate metabolite.Antimicrob Agents Chemother202642363837PubTator, text miningPubMed
Integrated Downstream Analysis and Epidemiological Modelling of Hantavirus Infection: From Host Transcriptomics to Transmission Dynamics.Pathogens202642347213PubTator, text miningPubMed

1 to 10 of 1,751

See all 1,751 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/129607

GET https://conductscience.org/api/genes/v1/129607/patents