Gene · 1300
COL10A1: collagen type X alpha 1 chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. COL10A1: collagen type X alpha 1 chain. Genes, record 1300. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1300
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q03692 | Collagen alpha-1(X) chain | 680 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents60
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 1085 | Q03692 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 120 | Q03692 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 762 | Q03692 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3205 | Q03692 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 3206 | Q03692 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5932 | Q03692 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5932 | Q03692 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 120 | Q03692 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 762 | Q03692 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1085 | Q03692 | Espacenet |
1 to 10 of 60
See all 60 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants950
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | COL10A1 papers | Newest fiscal year |
|---|---|---|---|
| P30AR073752 | Washington University Rheumatic Diseases Research Resource-based Center | 7 | 2025 |
| P30AR074992 | RESOURCE BASED CENTER FOR MUSCULOSKELETAL BIOLOGY AND MEDICINE | 7 | 2025 |
| P41EB021911 | Center for Modular Manufacturing of Structural Tissues | 6 | 2025 |
| U54GM115677 | Advance Clinical and Translational Research (Advance-CTR) | 5 | 2025 |
| T90DE021982 | Doctoral and Post-doctoral Training in Craniofacial Biology | 4 | 2025 |
| ZIADE000380 | The role of stem cells in skeletal health and disease | 4 | 2025 |
| K12EY016335 | Harvard-Vision Clinical Scientist Development Program | 3 | 2025 |
| P20GM103434 | West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | 3 | 2025 |
| P20GM121322 | Tumor Microenvironment-TME CoBRE | 3 | 2025 |
| P30AR069619 | Overall: Resource-based Center for Musculoskeletal Disorders Research (Overall Application) | 3 | 2025 |
1 to 10 of 950Source NIH's project files
See all 950 nih grantsPapers2,140
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Heart failure may promote breast cancer progression through a Col10a1-associated Tgf-β/Smad-EMT pathway. | Biol Direct | 2026 | 42806392 | PubTator, text mining | PubMed |
| In vitro chondrogenic differentiation is improved by the BMP7-derived peptide p[63-82]. | Peptides | 2026 | 42778025 | PubTator, text mining | PubMed |
| Analysis of the clinical diagnostic efficacy of the novel serum markers lipase F, gastrokine 2 and the collagen X-type α1 chain in gastric cancer. | J Med Biochem | 2026 | 42769816 | PubTator, text mining | PubMed |
| Oxygen Consumption Rate-Defined Phases Couple Metabolism to Matrix Dynamics in Chondrocyte-Mesenchymal Stromal Cell Co-Culture. | FASEB J | 2026 | 42750492 | PubTator, text mining | PubMed |
| Composition and Function of Decellularized Human Lung Extracellular Matrix from Congenital Pulmonary Airway Malformation. | J Clin Med | 2026 | 42739747 | PubTator, text mining | PubMed |
| Eugenol preserves chondrocyte extracellular matrix homeostasis by modulating the ALK1/ALK5-associated TGF-β/Smad signaling axis. | Front Pharmacol | 2026 | 42723961 | PubTator, text mining | PubMed |
| In vitro evaluation of hydroxyapatite, β-tricalcium phosphate, graphene oxide and zinc oxide for osteochondral regeneration under inflammatory conditions. | Mol Cell Biochem | 2026 | 42709332 | PubTator, text mining | PubMed |
| A truncated COL10A1 protein causes Schmid metaphyseal chondrodysplasia via protein downregulation and impairing α1 trimer formation and secretion. | Funct Integr Genomics | 2026 | 42706449 | PubTator, text mining | PubMed |
| Expanding the Clinical and Genetic Spectrum of Schmid Metaphyseal Chondrodysplasia: A Seven-Patient Series Including a Rare Homozygous COL10A1 Case. | Am J Med Genet A | 2026 | 42678355 | PubTator, text mining | PubMed |
| Does integrin α10β1 enrichment improve cartilage regeneration? Insights from an in vitro and ex vivo human chondral defect repair model. | Knee | 2026 | 42664717 | PubTator, text mining | PubMed |
1 to 10 of 2,140
See all 2,140 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1300
GET https://conductscience.org/api/genes/v1/1300/patents?page=2