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COL11A2: collagen type XI alpha 2 chain

1 protein, 9 patents, 2 drugs, 66 trials, 8,256 NIH grants and 21,061 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCOL11A2HGNC
Namecollagen type XI alpha 2 chainHGNC
NCBI Gene ID1302NCBI Gene
HGNC IDHGNC:2187HGNC
EnsemblENSG00000204248NCBI Gene
AliasesDFNA13, DFNB53, FBCG2, HKE5, OSMEDA, OSMEDB, PARP, STL3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P13942Collagen alpha-2(XI) chain1,7360Ensembl, GeneID, HGNCUniProt

Patents 9

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025032204 A2025-03-1126608P13942Espacenet
EP 4461818 A22024-11-1326608P13942Espacenet
JP 2023058610 A2023-04-2526608P13942Espacenet
US 11446398 B22022-09-2019096P13942Espacenet
JP 2022524081 A2022-04-27122067P13942Espacenet
JP 2020508652 A2020-03-2626608P13942Espacenet
US 9878056 B22018-01-301135P13942Espacenet
JP 2017141230 A2017-08-175203P13942Espacenet
JP 2015517995 A2015-06-255203P13942Espacenet

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
COLLAGENASE CLOSTRIDIUM HISTOLYTICUMCHEMBL2108709Collagen hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL
OCRIPLASMINCHEMBL2095222Collagen hydrolytic enzymeHYDROLYTIC ENZYMEChEMBL

Trials 66

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06169319COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE2ClinicalTrials.gov
NCT06151197COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT06065436COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT05646602COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT05254457COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT05152173COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE2ClinicalTrials.gov
NCT04874870COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE3ClinicalTrials.gov
NCT04680156COLLAGENASE CLOSTRIDIUM HISTOLYTICUMClinicalTrials.gov
NCT04496167COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE22023-09-13ClinicalTrials.gov
NCT04236635COLLAGENASE CLOSTRIDIUM HISTOLYTICUMPHASE22022-04-12ClinicalTrials.gov

NIH grants 8256

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant2872,025NIH's project files
P30CA008748Cancer Center Support Grant1762,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant602,025NIH's project files
P30CA016058Cancer Center Support Grant512,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant512,025NIH's project files
P30CA006973Regional Oncology Research Center482,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program482,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028452,025NIH's project files
P30CA047904Cancer Center Support Grant422,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant392,025NIH's project files

Papers 21061

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824309PubTator, text miningPubMed
42823178PubTator, text miningPubMed
42816529PubTator, text miningPubMed
42805173PubTator, text miningPubMed
42802426PubTator, text miningPubMed
42797381PubTator, text miningPubMed
42797333PubTator, text miningPubMed
42794557PubTator, text miningPubMed
42792755PubTator, text miningPubMed
42779790PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license