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Gene · 131450

CD200R1: CD200 receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CD200R1: CD200 receptor 1. Genes, record 131450. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/131450

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Gene

Symbol
CD200R1
HGNC
Name
CD200 receptor 1
HGNC
NCBI Gene ID
131450
NCBI Gene
HGNC ID
HGNC:24235
HGNC
Ensembl
ENSG00000163606
NCBI Gene
Aliases
CD200R, HCRTR2, MOX2R, OX2R
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8TD46Cell surface glycoprotein CD200 receptor 13481Ensembl, GeneID, HGNC

Source UniProt

Patents29

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440488Q8TD46Espacenet
EP 4650780 A22025-11-194728Q8TD46Espacenet
JP 2025147176 A2025-10-062256Q8TD46Espacenet
JP 2025517970 A2025-06-124728Q8TD46Espacenet
EP 4526347 A12025-03-26172Q8TD46Espacenet
JP 2025028160 A2025-02-282256Q8TD46Espacenet
KR 1020250010750 A2025-01-212256Q8TD46Espacenet
JP 2024109657 A2024-08-142263Q8TD46Espacenet
US 11761963 B22023-09-1942Q8TD46Espacenet
US 11719707 B22023-08-0813Q8TD46Espacenet

1 to 10 of 29

See all 29 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants777

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCD200R1 papersNewest fiscal year
P30CA016058Cancer Center Support Grant72025
P51OD011092Support for National Primate Research Center52025
R01CA208353Elucidation of Human Natural Killer Cell Development42025
ZIAAI001124Translational Research: Host-Pathogen Interactions in Patient Fungal Diseases42025
P30AI045008Penn Center for AIDS Research32025
R35CA210087Human natural killer cells: Advancing biology and clinical applications32025
U19AI057229Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro32025
ZIAAI001123Molecular Pathobiology of Cryptococcus neoformans32025
P01CA018029Adult Leukemia Research Center22025
P01CA225517Immunobiology and Immune Therapy for Merkel Cell Carcinoma22025

1 to 10 of 777Source NIH's project files

See all 777 nih grants

Papers1,628

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Bioinformatics Analysis of T-cell Exhaustion Genes in Pediatric Allergic Rhinitis and their Clinical Diagnostic Significance.Endocr Metab Immune Disord Drug Targets202642813621PubTator, text miningPubMed
Macrophage phagocytosis checkpoints in DLBCL immunotherapy: an evidence-maturity framework from CD47 to CD200.Front Oncol202642798844PubTator, text miningPubMed
CD200-CD200R as a myeloid immune checkpoint in solid tumors: mechanisms, context-dependent functions, and therapeutic opportunities.Front Immunol202642761652PubTator, text miningPubMed
Reprogramming engineered autologous T cells to overcome resistance in patients with Merkel cell carcinoma.Sci Transl Med202642715345PubTator, text miningPubMed
Evaluation of the predictive value of sCD200 and sCD200R for disease severity and relapse in myasthenia gravis.Clin Chim Acta202642700883PubTator, text miningPubMed
CD200 is a potent new growth factor in Multiple Myeloma dependent on IGF1 receptor signaling.Transl Oncol202642664786PubTator, text miningPubMed
Retraction: Bone marrow mesenchymal stem cells alleviate smoke inhalation injury by regulating alveolar macrophage polarization via the CD200-CD200R pathway.Front Immunol202642602831PubTator, text miningPubMed
Radiation-induced CD200+ tumor-associated macrophages suppress eosinophil-mediated antitumor immunity through CD200R signaling in hepatocellular carcinoma.Cell Mol Immunol202642595852PubTator, text miningPubMed
Tumor cell-derived extracellular vesicles foster the immunosuppressive landscape of pancreatic cancer.J Clin Invest202642390925PubTator, text miningPubMed
CD200R protects against ulcerative colitis by regulating macrophage polarization and intestinal barrier function: evidence from human patients and mouse disease models.Free Radic Biol Med202642349804PubTator, text miningPubMed

1 to 10 of 1,628

See all 1,628 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/131450

GET https://conductscience.org/api/genes/v1/131450/patents?page=2