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Gene · 1317

SLC31A1: solute carrier family 31 member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC31A1: solute carrier family 31 member 1. Genes, record 1317. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1317

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Gene

Symbol
SLC31A1
HGNC
Name
solute carrier family 31 member 1
HGNC
NCBI Gene ID
1317
NCBI Gene
HGNC ID
HGNC:11016
HGNC
Ensembl
ENSG00000136868
NCBI Gene
Aliases
COPT1, CTR1, NSCT, hCTR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15431High affinity copper uptake protein 11903Ensembl, GeneID, HGNC

Source UniProt

Patents43

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464446O15431Espacenet
EP 4650780 A22025-11-199434O15431Espacenet
JP 2025529142 A2025-09-044158O15431Espacenet
US 12371689 B22025-07-294158O15431Espacenet
JP 2025517970 A2025-06-129434O15431Espacenet
US 11446398 B22022-09-2081307O15431Espacenet
US 11400116 B22022-08-022489O15431Espacenet
JP 2022524081 A2022-04-27184278O15431Espacenet
US 11078247 B22021-08-0310482O15431Espacenet
JP 2019054813 A2019-04-11244881O15431Espacenet

1 to 10 of 43

See all 43 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants769

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC31A1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant132025
R01GM079465Chemical Probes to Study Copper Biology112025
R01DK071865Molecular Mechanisms of Active Copper Transport92025
T32CA121938UCSD Cancer Center Training Program in Drug Development82025
P30CA021765Cancer Center Support Grant (CCSG)72025
R35GM124749Molecular and Cellular Mechanisms of Copper-Dependent Nutrient Signaling and Metabolism72025
P30ES013508Center of Excellence in Environmental Toxicology52025
I01BX001232Cu importer CTR1 Cys189 oxidation in atherosclerosis32025
P20GM113226Hepatobiology and Toxicology COBRE32025
P30CA014236Cancer Center Support Grant (CCSG)32025

1 to 10 of 769Source NIH's project files

See all 769 nih grants

Papers1,953

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Roles of cuproptosis in central nervous system tumors: from molecular mechanisms to therapeutic prospects.Front Cell Dev Biol202642812787PubTator, text miningPubMed
Unveiling Disulfidptosis and Cuproptosis Vulnerabilities in Pterygium: A Transcriptomic Analysis and In-Silico Drug Repurposing Strategy.Genes (Basel)202642792999PubTator, text miningPubMed
Cuproptosis: a novel mechanism linking placental metabolic stress to trophoblast injury in preeclampsia.Front Endocrinol (Lausanne)202642780476PubTator, text miningPubMed
DHA Targets RAB1B to Mediate the Driving Force Transmission of Copper Ion Vesicular Endocytosis Under Copper Overload for Promoting Cuproptosis and Ferroptosis in Hepatic Stellate Cells.Int J Biol Sci202642694667PubTator, text miningPubMed
Copper, cuproptosis, and cancer: biology concepts of a novel cell death.Apoptosis202642693224PubTator, text miningPubMed
Cuproptosis: a novel mechanism and 3PM-oriented therapeutic strategy for cancer.EPMA J202642682874PubTator, text miningPubMed
Functional role of LAMC1 in modulating cuproptosis in glioma cells.Biochim Biophys Acta Mol Cell Res202642665028PubTator, text miningPubMed
Plasma anti-ATP7A/ATP7B/COPT1 autoantibodies as potential biomarkers for breast cancer detection.Clin Immunol202642660209PubTator, text miningPubMed
Divergent effects of copper and cisplatin on the endocytic trafficking of copper transporter-1.FEBS Lett202642612009PubTator, text miningPubMed
DLST drives lung adenocarcinoma progression by modulating cuproptosis-related copper homeostasis and apoptosis via an EP300-dependent mechanism.Transl Oncol202642600375PubTator, text miningPubMed

1 to 10 of 1,953

See all 1,953 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1317

GET https://conductscience.org/api/genes/v1/1317/patents?page=2