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Gene · 1327

COX4I1: cytochrome c oxidase subunit 4I1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. COX4I1: cytochrome c oxidase subunit 4I1. Genes, record 1327. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1327

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
COX4I1
HGNC
Name
cytochrome c oxidase subunit 4I1
HGNC
NCBI Gene ID
1327
NCBI Gene
HGNC ID
HGNC:2265
HGNC
Ensembl
ENSG00000131143
NCBI Gene
Aliases
COX IV-1, COX4, COX4-1, COXIV, COXIV-1, MC4DN16
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13073Cytochrome c oxidase subunit 4 isoform 1, mitochondrial1693Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1442798P13073Espacenet
EP 4650780 A22025-11-191455P13073Espacenet
JP 2025529142 A2025-09-041091P13073Espacenet
US 12371689 B22025-07-291091P13073Espacenet
JP 2025517970 A2025-06-121455P13073Espacenet
US 11519913 B22022-12-061P13073Espacenet
US 11446398 B22022-09-2021805P13073Espacenet
US 11446398 B22022-09-2021812P13073Espacenet
US 11446398 B22022-09-2021813P13073Espacenet
US 11400116 B22022-08-022491P13073Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,019

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA047904Cancer Center Support Grant262025
P30CA016672Cancer Center Support Grant242025
P30CA008748Cancer Center Support Grant102025
R35GM118141Mitochondrial Biogenesis in Health and Disease92025
P30CA010815Consolidated Basic Cancer Research Program82025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center72025
P30CA006516Dana-Farber/Harvard Cancer Center62025
P30CA046934University of Colorado Cancer Center Support Grant62025
P30DK020572Michigan Diabetes Research Center (MDRC)62025
P30DK056341Washington University Nutrition Obesity Research Center62025

1 to 10 of 3,019Source NIH's project files

See all 3,019 nih grants

Papers4,132

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42815086PubTator, text miningPubMed
42805312PubTator, text miningPubMed
42771222PubTator, text miningPubMed
42710102PubTator, text miningPubMed
42663295PubTator, text miningPubMed
42644246PubTator, text miningPubMed
42616073PubTator, text miningPubMed
42589431PubTator, text miningPubMed
42586397PubTator, text miningPubMed
42562774PubTator, text miningPubMed

1 to 10 of 4,132

See all 4,132 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1327

GET https://conductscience.org/api/genes/v1/1327/patents?page=2