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Gene · 133522

PPARGC1B: PPARG coactivator 1 beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. PPARGC1B: PPARG coactivator 1 beta. Genes, record 133522. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/133522

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Gene

Symbol
PPARGC1B
HGNC
Name
PPARG coactivator 1 beta
HGNC
NCBI Gene ID
133522
NCBI Gene
HGNC ID
HGNC:30022
HGNC
Ensembl
ENSG00000155846
NCBI Gene
Aliases
ERRL1, PERC, PGC-1(beta), PGC1B, PPARAGCIβ
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q86YN6Peroxisome proliferator-activated receptor gamma coactivator 1-beta1,0232Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1457480Q86YN6Espacenet
EP 4640849 A22025-10-29666Q86YN6Espacenet
EP 4641201 A22025-10-294421Q86YN6Espacenet
JP 2025519096 A2025-06-24666Q86YN6Espacenet
JP 2025517969 A2025-06-124421Q86YN6Espacenet
US 11446398 B22022-09-2062166Q86YN6Espacenet
JP 2022524081 A2022-04-27165137Q86YN6Espacenet
US 11136562 B22021-10-05284Q86YN6Espacenet
JP 2019054813 A2019-04-11237915Q86YN6Espacenet
EP 3399991 A12018-11-14284Q86YN6Espacenet

1 to 10 of 16

See all 16 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,634

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitlePPARGC1B papersNewest fiscal year
P30DK020572Michigan Diabetes Research Center (MDRC)122025
P30DK056341Washington University Nutrition Obesity Research Center72025
P30CA016672Cancer Center Support Grant62025
P30DK036836Diabetes Research Center62025
P30DK063491Diabetes Research Center (DRC)62025
R01EY010804Setting the Stage for Replacement of Mitochondrial Genes62025
P30CA008748Cancer Center Support Grant52025
P30CA021765Cancer Center Support Grant (CCSG)52025
P30CA036727Buffett Cancer Center Support Grant52025
P30DK056350Nutrition Obesity Research Center (NORC)52025

1 to 10 of 1,634Source NIH's project files

See all 1,634 nih grants

Papers2,180

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correlation analysis of PGC-1β, HIF-1α and RETN with the degree of joint destruction in gouty arthritis.J Med Biochem202642780816PubTator, text miningPubMed
Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation.Circ Res202642594169PubTator, text miningPubMed
Inhibition of PGC1β-dependent mitochondrial biogenesis enhances EGFR-targeted therapy in lung cancer.EMBO Mol Med202642533181PubTator, text miningPubMed
The impact of nationwide folic acid fortification on genetic variants associated with conotruncal heart defects.Res Sq202642427871PubTator, text miningPubMed
Landscape of N6-methyladenosine (m6A) methylation in porcine cells identifies candidate genes associated with porcine epidemic diarrhea virus infection.Front Microbiol202642232905PubTator, text miningPubMed
Ferulic acid ameliorates high-fat diet-induced hyperlipidemia in mice via suppressing the PGC-1β/miR-378a-3p axis.J Nutr Biochem202642191002PubTator, text miningPubMed
Monocyte Chemokines Enhance Atherosclerotic Plaque Necrosis After Bacterial Kidney Infection.FASEB J202641930659PubTator, text miningPubMed
Mitochondrial Long Non-Coding RNAs in Gynecological Cancers: Pathogenic Signaling Pathways and Therapeutic Opportunities.Curr Issues Mol Biol202641899413PubTator, text miningPubMed
Emergency physicians' perceptions and optimization strategies for diagnostic imaging overuse in Somalia.BMC Emerg Med202641877011PubTator, text miningPubMed
Fueling or Fighting Cancer? The Thermogenic Paradox of Brown Adipose Tissue.Curr Obes Rep202641848823PubTator, text miningPubMed

1 to 10 of 2,180

See all 2,180 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/133522

GET https://conductscience.org/api/genes/v1/133522/patents