Gene · 133522
PPARGC1B: PPARG coactivator 1 beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. PPARGC1B: PPARG coactivator 1 beta. Genes, record 133522. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/133522
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q86YN6 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta | 1,023 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 57480 | Q86YN6 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 666 | Q86YN6 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4421 | Q86YN6 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 666 | Q86YN6 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4421 | Q86YN6 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 62166 | Q86YN6 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 165137 | Q86YN6 | Espacenet |
| US 11136562 B2 | 2021-10-05 | 284 | Q86YN6 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 237915 | Q86YN6 | Espacenet |
| EP 3399991 A1 | 2018-11-14 | 284 | Q86YN6 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,634
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | PPARGC1B papers | Newest fiscal year |
|---|---|---|---|
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 12 | 2025 |
| P30DK056341 | Washington University Nutrition Obesity Research Center | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| P30DK036836 | Diabetes Research Center | 6 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 6 | 2025 |
| R01EY010804 | Setting the Stage for Replacement of Mitochondrial Genes | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA036727 | Buffett Cancer Center Support Grant | 5 | 2025 |
| P30DK056350 | Nutrition Obesity Research Center (NORC) | 5 | 2025 |
1 to 10 of 1,634Source NIH's project files
See all 1,634 nih grantsPapers2,180
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Correlation analysis of PGC-1β, HIF-1α and RETN with the degree of joint destruction in gouty arthritis. | J Med Biochem | 2026 | 42780816 | PubTator, text mining | PubMed |
| Extracellular Vesicles in Cardiovascular Disease: Intercellular Signaling, Liquid Biopsy Biomarkers, and Therapeutic Translation. | Circ Res | 2026 | 42594169 | PubTator, text mining | PubMed |
| Inhibition of PGC1β-dependent mitochondrial biogenesis enhances EGFR-targeted therapy in lung cancer. | EMBO Mol Med | 2026 | 42533181 | PubTator, text mining | PubMed |
| The impact of nationwide folic acid fortification on genetic variants associated with conotruncal heart defects. | Res Sq | 2026 | 42427871 | PubTator, text mining | PubMed |
| Landscape of N6-methyladenosine (m6A) methylation in porcine cells identifies candidate genes associated with porcine epidemic diarrhea virus infection. | Front Microbiol | 2026 | 42232905 | PubTator, text mining | PubMed |
| Ferulic acid ameliorates high-fat diet-induced hyperlipidemia in mice via suppressing the PGC-1β/miR-378a-3p axis. | J Nutr Biochem | 2026 | 42191002 | PubTator, text mining | PubMed |
| Monocyte Chemokines Enhance Atherosclerotic Plaque Necrosis After Bacterial Kidney Infection. | FASEB J | 2026 | 41930659 | PubTator, text mining | PubMed |
| Mitochondrial Long Non-Coding RNAs in Gynecological Cancers: Pathogenic Signaling Pathways and Therapeutic Opportunities. | Curr Issues Mol Biol | 2026 | 41899413 | PubTator, text mining | PubMed |
| Emergency physicians' perceptions and optimization strategies for diagnostic imaging overuse in Somalia. | BMC Emerg Med | 2026 | 41877011 | PubTator, text mining | PubMed |
| Fueling or Fighting Cancer? The Thermogenic Paradox of Brown Adipose Tissue. | Curr Obes Rep | 2026 | 41848823 | PubTator, text mining | PubMed |
1 to 10 of 2,180
See all 2,180 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/133522
GET https://conductscience.org/api/genes/v1/133522/patents