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Gene · 134864

TAAR1: trace amine associated receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TAAR1: trace amine associated receptor 1. Genes, record 134864. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/134864

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Gene

Symbol
TAAR1
HGNC
Name
trace amine associated receptor 1
HGNC
NCBI Gene ID
134864
NCBI Gene
HGNC ID
HGNC:17734
HGNC
Ensembl
ENSG00000146399
NCBI Gene
Aliases
TA1, TAR1, TRAR1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96RJ0Trace amine-associated receptor 133917Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467261Q96RJ0Espacenet
JP 2025529142 A2025-09-044565Q96RJ0Espacenet
US 12371689 B22025-07-294565Q96RJ0Espacenet
EP 4541896 A12025-04-2331Q96RJ0Espacenet
JP 2025010185 A2025-01-2031Q96RJ0Espacenet
US 12083116 B22024-09-104Q96RJ0Espacenet
US 12006548 B22024-06-11559Q96RJ0Espacenet
JP 2023184465 A2023-12-2831Q96RJ0Espacenet
WO 2023243495 A2023-12-2131Q96RJ0Espacenet
US 11446398 B22022-09-2089353Q96RJ0Espacenet

1 to 10 of 50

See all 50 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
ULOTARONTCHEMBL4650337Trace amine-associated receptor 1 agonistAGONIST

Source ChEMBL

Trials26

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07225712ULOTARONTPHASE3ClinicalTrials.gov
NCT06894212ULOTARONTPHASE3ClinicalTrials.gov
NCT05848700ULOTARONTPHASE1ClinicalTrials.gov
NCT05741528ULOTARONTPHASE32025-11-12ClinicalTrials.gov
NCT05729373ULOTARONTPHASE2/PHASE3ClinicalTrials.gov
NCT05628103ULOTARONTPHASE32025-11-12ClinicalTrials.gov
NCT05593029ULOTARONTPHASE2ClinicalTrials.gov
NCT05542264ULOTARONTPHASE1ClinicalTrials.gov
NCT05463770ULOTARONTPHASE1ClinicalTrials.gov
NCT05402111ULOTARONTPHASE1ClinicalTrials.gov

1 to 10 of 26

See all 26 trials

NIH grants638

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTAAR1 papersNewest fiscal year
P60AA010760Behavioral Genomics of Alcohol Neuroadaptation42025
T32AA007468BIOLOGICAL BASES OF ALCOHOLISM42025
R01AI109023Defining P. falciparum resistance to artemisinin-based combination therapies32025
R01AI124678Elucidating the molecular basis of piperaquine resistance in Plasmodium falciparum32025
R24HD000836Laboratory of Developmental Biology32025
P20GM103442ND INBRE Health & the Environment22025
P30DK065988UNC Cystic Fibrosis Research and Translation Core Center22025
P30ES019776HERCULES: Exposome Research Center22025
P30MH092177Comprehensive NeuroHIV Center22025
R01AI147628Leveraging PfCRT Structure to Discern Function and Predict Emergence of Drug-Resistant Malaria22025

1 to 10 of 638Source NIH's project files

See all 638 nih grants

Papers1,472

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Clinical Applications and Evidence Landscape of Thymosin Alpha 1 as an Immunomodulatory Adjunct in Cancer Care: A Scoping Review.Pharmaceuticals (Basel)202642797537PubTator, text miningPubMed
Thymosin Alpha-1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis.Adv Sci (Weinh)202642693587PubTator, text miningPubMed
Novel Insights into the Pleiotropic Neuroprotective Action of Synthetic Halogen Free Thyronamine-like Analogues.Molecules202642653915PubTator, text miningPubMed
Thymosin α-1 in cancer therapy: Immunomodulatory mechanisms, clinical applications, and translational perspectives.Eur J Pharmacol202642641753PubTator, text miningPubMed
Concurrent downregulation of TAAR1 and NQO1 in individuals with isolated methamphetamine use: Implications for dopaminergic and oxidative stress-related biology.Prog Neuropsychopharmacol Biol Psychiatry202642641678PubTator, text miningPubMed
Dynamic evolution of retroviral envelope-derived sequences in primates.Virus Evol202642583397PubTator, text miningPubMed
Trace Amine-associated Receptor 1 Agonists for Treatment of Substance use Disorder: Evidence from Rodent Behavioral Studies.Curr Neuropharmacol202642576581PubTator, text miningPubMed
TAAR Immunopharmacology.Handb Exp Pharmacol202642463873PubTator, text miningPubMed
TAAR1 Potential for Treatment of Stress Disorders.Handb Exp Pharmacol202642463872PubTator, text miningPubMed
Sex Differences in Trace Amine-Associated Receptor Signalling.Handb Exp Pharmacol202642463870PubTator, text miningPubMed

1 to 10 of 1,472

See all 1,472 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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