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COX8A: cytochrome c oxidase subunit 8A

1 protein, 22 patents, 0 drugs, 0 trials, 5,335 NIH grants and 12,682 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCOX8AHGNC
Namecytochrome c oxidase subunit 8AHGNC
NCBI Gene ID1351NCBI Gene
HGNC IDHGNC:2294HGNC
EnsemblENSG00000176340NCBI Gene
AliasesCOX, COX8, COX8-2, COX8L, MC4DN15, VIII, VIII-LNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10176Cytochrome c oxidase subunit 8A, mitochondrial694Ensembl, GeneID, HGNCUniProt

Patents 22

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195364P10176Espacenet
JP 2025529142 A2025-09-041101P10176Espacenet
US 12371689 B22025-07-291101P10176Espacenet
JP 2025517970 A2025-06-125364P10176Espacenet
US 11446398 B22022-09-2021866P10176Espacenet
US 11400116 B22022-08-022959P10176Espacenet
JP 2022524081 A2022-04-27124837P10176Espacenet
US 11078247 B22021-08-032503P10176Espacenet
US 10918740 B22021-02-167273P10176Espacenet
US 10869935 B22020-12-227273P10176Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5335

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant242,025NIH's project files
R01EY010804Setting the Stage for Replacement of Mitochondrial Genes152,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
R01NS083726Personalized Functional Genomics for Mitochondrial Encephalopathy Gene Discovery122,025NIH's project files
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies112,025NIH's project files
P30AG028740University of Florida Older Americans Independence Center (OAIC)102,025NIH's project files
P30CA056036Translational Research in Cancer102,025NIH's project files
P30ES013508Center of Excellence in Environmental Toxicology102,025NIH's project files
P50CA097190Head and Neck Cancer SPORE92,025NIH's project files
ZIAES065078Molecular Characterization Of The Mitochondrial Dna Polymerase92,025NIH's project files

Papers 12682

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818062PubTator, text miningPubMed
42815861PubTator, text miningPubMed
42770367PubTator, text miningPubMed
42750209PubTator, text miningPubMed
42746104PubTator, text miningPubMed
42730943PubTator, text miningPubMed
42726329PubTator, text miningPubMed
42719759PubTator, text miningPubMed
42712955PubTator, text miningPubMed
42686586PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license