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Gene · 1361

CPB2: carboxypeptidase B2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CPB2: carboxypeptidase B2. Genes, record 1361. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/1361

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Gene

Symbol
CPB2
HGNC
Name
carboxypeptidase B2
HGNC
NCBI Gene ID
1361
NCBI Gene
HGNC ID
HGNC:2300
HGNC
Ensembl
ENSG00000080618
NCBI Gene
Aliases
CPU, PCPB, TAFI
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q96IY4Carboxypeptidase B242310Ensembl, GeneID, HGNC

Source UniProt

Patents37

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440056Q96IY4Espacenet
EP 4650780 A22025-11-19161Q96IY4Espacenet
EP 4641201 A22025-10-29129Q96IY4Espacenet
JP 2025147176 A2025-10-063436Q96IY4Espacenet
JP 2025147176 A2025-10-063437Q96IY4Espacenet
JP 2025529142 A2025-09-045989Q96IY4Espacenet
US 12371689 B22025-07-295989Q96IY4Espacenet
JP 2025517969 A2025-06-12129Q96IY4Espacenet
JP 2025517970 A2025-06-12161Q96IY4Espacenet
JP 2025062604 A2025-04-1411852Q96IY4Espacenet

1 to 10 of 37

See all 37 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants843

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCPB2 papersNewest fiscal year
T32GM008315Mechanisms of Trauma-Induced Coagulopathy162025
R01HL142975Regulation of Protein C Pathways82025
T32HL098049T32 Training Program in Mechanisms and Innovation in Vascular Disease62025
R01HL101972Characterization of Coagulation Factor-platelet Interactions: Role of FXI52025
R01HL101917Protease Activated Receptor and Thrombomodulin Signaling by coagulation proteases42025
R35GM119526Mechanistic Elucidation and Targeted Therapy of Organ Injury and Inflammation following Trauma42025
P30CA006973Regional Oncology Research Center32025
R01HL049413Structural basis of prothrombin activation32025
P30CA068485Cancer Center Support Grant22025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment22025

1 to 10 of 843Source NIH's project files

See all 843 nih grants

Papers2,519

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Efficacy of rt-PA versus Urokinase in early time windows for minimally invasive intracerebral hemorrhage evacuation and exploratory TAFI pharmacogenomics.Front Neurol202642609371PubTator, text miningPubMed
Incident chronic kidney disease risk and the predictive value of the uric acid-to-HDL ratio in lean and non-lean MASLD: a prospective cohort and multi-omics study.Int Urol Nephrol202642572097PubTator, text miningPubMed
Thrombomodulin Gly430Ser mutation attenuates the affinity with thrombin and contributes to thrombosis development.J Thromb Thrombolysis202642521976PubTator, text miningPubMed
Electrode-Triggered niche differentiation and endogenous electron cycling boost bioremediation of mixed aromatic contaminants in oligotrophic groundwater.Water Res202642520702PubTator, text miningPubMed
Novel biomarkers for the differential diagnosis of paediatric MYH9-related diseases and immune thrombocytopenia revealed by plasma proteomics.Br J Haematol202642509019PubTator, text miningPubMed
[Diagnosis and management of bleeding disorders caused by hyperfibrinolysis (designated intractable disease No. 347 in Japan)].Rinsho Ketsueki202642419995PubTator, text miningPubMed
Thromboinflammation and hemostatic activation drive early mortality risk in pulmonary embolism.Res Pract Thromb Haemost202642293734PubTator, text miningPubMed
Emerging strategies in venous thromboembolism: a narrative review of pharmacological innovations.Thromb J202642260521PubTator, text miningPubMed
SEER sonorheometry enhances fibrinolysis detection during liver transplantation with heparin.Blood Coagul Fibrinolysis202642257489PubTator, text miningPubMed
Identification of a Prognostic Gene Signature Based on Lenvatinib Resistance in Hepatocellular Carcinoma with Functional Validation of the Key Gene CPB2.J Hepatocell Carcinoma202642158333PubTator, text miningPubMed

1 to 10 of 2,519

See all 2,519 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/1361

GET https://conductscience.org/api/genes/v1/1361/patents?page=2